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Performance test of urine bioassay through participation in the NRIP

NRIP 참여를 통한 소변시료 바이오어세이 성능검사

  • Ha, Wi-Ho (National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences) ;
  • Yoo, Jaeryong (National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences) ;
  • Yoon, Seokwon (National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences) ;
  • Lee, Seung-Sook (National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences) ;
  • Kim, Jong Kyoung (Department of Nuclear Engineering, Hanyang University)
  • 하위호 (한국원자력의학원 국가방사선비상진료센터) ;
  • 유재룡 (한국원자력의학원 국가방사선비상진료센터) ;
  • 윤석원 (한국원자력의학원 국가방사선비상진료센터) ;
  • 이승숙 (한국원자력의학원 국가방사선비상진료센터) ;
  • 김종경 (한양대학교 원자력공학과)
  • Received : 2014.02.04
  • Accepted : 2014.03.17
  • Published : 2014.06.30

Abstract

Urine bioassay has been widely used for internal dosimetry due to simple process of sampling and measurement. In this paper, we participated in the NRIP (NIST Radiochemistry Intercomparison Program) hosted by US NIST to carry out a reliable performance test of urine bioassay and introduced the measurement method and results of NRIP-2013. In customary exercise with 60 days of reporting time, bioassay results of 12 radionuclides in the synthetic urine samples were acceptable based on the performance criteria of ANSI N13.30. In emergency preparedness exercise with 8 hours of reporting time, bioassay results of 9 radionuclides showed that differences ranged from -35% to 45%. However, we concluded that urine bioassay applied for emergency preparedness exercise would be applicable for rapid screening and estimation of internal exposure within a difference of ${\pm}45%$ in the event of radiological accidents.

소변시료 바이오어세이는 분석설비가 비교적 간단하고 시료 채취가 용이하여 내부피폭선량 평가를 위하여 널리 사용되고 있는 대표적인 간접측정법이다. 본 연구에서는 소변시료 바이오어세이 결과에 대해 보다 객관적인 성능검사를 수행하기 위하여 미국 NIST에서 주관한 NRIP (NIST raiochemistry inercomparison pogram)에 참여한 결과를 소개하였다. 60일간의 분석기간 동안 인공합성소변으로 제작된 검사시료의 방사능분석결과를 보고하는 cstomary exercise에서는 12가지 방사성핵종에 대한 측정 결과 ANSI N13.30에서 제시하는 성능검사 기준을 모두 만족하는 것으로 확인되었다. 비상상황에 대비하여 8시간 이내에 방사능분석결과를 신속하게 보고하는 eergency preparedness exercise에서는 9가지 방사성핵종에 대하여 -35 ~ 45%의 차이를 나타내어 확인된 오차범위 내에서 비상시 신속한 내부피폭 분류에 적용하기에 적합한 것으로 확인되었다.

Keywords

References

  1. International Atomic Energy Agency. Direct methods for measuring radionuclides in the human body. IAEA Safety Series No. 114. 1995.
  2. International Atomic Energy Agency. Indirect methods for assessing intakes of radionuclides causing occupational exposure. IAEA Safety Reports Series No. 18. 2000.
  3. International Organization for Standardization. Radiation Protection - Performance criteria for radiobioassay. ISO 28218. 2010.
  4. American National Standard Institute. American National Standard - Performance criteria for radiobioassay. ANSI/HPS N.13.30. 1996.
  5. American National Standard Institute. American National Standard - Performance criteria for radiobioassay. ANSI/HPS N.13.30. 2011.
  6. Wu Z, Inn KGW, Lin Z, McMahon CA, Karam LR. NIST radiochemistry intercomparison program: a summary of four-year performance evaluation study. Appl. Radiat. Isot. 2002;56:379-385. https://doi.org/10.1016/S0969-8043(01)00218-4
  7. Nour S, LaRosa J, Inn KGW. Emergency radiobioassay preparedness exercises through the NIST radiochemistry intercomparison program. Health Phys. 2011;101(2):170-175. https://doi.org/10.1097/HP.0b013e3182149823
  8. Inn KGW, Outola I, Nour S, Kurosaki H, Albin L, Berne A. Radioanalytical emergency response exercise. J. Radioanal. Nucl. Chem. 2006;269(2):351-360. https://doi.org/10.1007/s10967-006-0391-3
  9. Maxwell SL. Rapid analysis of emergency urine and water samples. J. Radioanal. Nucl. Chem. 2008;275(3):497-502. https://doi.org/10.1007/s10967-007-7084-4
  10. American National Standard Institute. American National Standard - Traceability of radioactive sources to the National Institute of Standard and Technology (NIST) and associated instrument quality control. ANSI N.42.22. 1995.