보건행정학회지 (Health Policy and Management)

  • 제24권2호
  • /
  • Pages.120-127
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  • 2014
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  • 1225-4266(pISSN)
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  • 2289-0149(eISSN)
한국보건행정학회 (Korean Academy of Health Policy and Management)
권호 표지
DOI QR코드

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의약품 처방·조제지원서비스(Drug Utilization Review)사업이 병용금기 처방률에 미치는 영향

The Effect of Korean Prospective Drug Utilization Review Program on the Prescription Rate of Drug-Drug Interactions

  • 김동숙 (건강보험심사평가원 연구조정실) ;
  • 박주희 (건강보험심사평가원 연구조정실) ;
  • 전하림 (건강보험심사평가원 연구조정실) ;
  • 박찬미 (건강보험심사평가원 연구조정실) ;
  • 강현아 (건강보험심사평가원 연구조정실)
  • Kim, Dong-Sook (Research Center, Health Insurance Review & Assessment Service) ;
  • Park, Juhee (Research Center, Health Insurance Review & Assessment Service) ;
  • Jeon, Ha-Rim (Research Center, Health Insurance Review & Assessment Service) ;
  • Park, Chanmi (Research Center, Health Insurance Review & Assessment Service) ;
  • Kang, Hyeun Ah (Research Center, Health Insurance Review & Assessment Service)
  • 투고 : 2014.03.24
  • 심사 : 2014.06.17
  • 발행 : 2014.06.30
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초록

Background: Since December 2010, online computerized prospective drug utilization review (pDUR) has been implemented in Korea. pDUR involves the review of each prescription before the medication is dispensed to the individual patient. The pDUR is performed electronically by Health Insurance Review & Assessment Service (HIRA), which is a Korean governmental agency, and then HIRA provides medical institutions and pharmacies with information that can be helpful to them in preventing potential drug problems such as drug/drug interactions or ingredient duplication. The aim of this study was to assess the impact of the Korean pDUR implementation on the proportion of drug-drug interactions (DDIs) using claims data from HIRA. Methods: A before-after comparison of the prevalence of DDIs between prescription was conducted, using HIRA administrative claims data of medical institution from January 2010 to December 2011. The analysis unit was the prescription issued and pairs before and after. The main outcome measures were the proportion of DDIs within- (control group) or between- physician encounters. To examine the difference, a paired t-test was applied. Results: We found that DDIs proportion between prescription decreased significantly (t=3.04, p=0.0026) after the implementation of pDUR, whereas there is no significant reduction within prescription (t=1.15, p=0.2518). With respect to the prevalence of DDIs between drug groups, the most dramatic reduction was occurred between 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors and anti-fungal agents. Conclusion: It seems effective that giving a direct feedback to prescribers by a prospective DUR. Further research is needed to assess the impact of DUR to final outcomes such as hospitalization.

키워드

참고문헌

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피인용 문헌

  1. Between government policy, clinical autonomy, and market demands: a qualitative study of the impact of the Prescribing Analysis System on behavior of physicians in South Korea vol.15, pp.1, 2015, https://doi.org/10.1186/s12913-015-1059-x
  2. New Alert Override Codes for the Drug Utilization Review System Derived from Outpatient Prescription Data from a Tertiary Teaching Hospital in Korea vol.22, pp.1, 2016, https://doi.org/10.4258/hir.2016.22.1.39
  3. Effect of providing drug utilization review information on tricyclic antidepressant prescription in the elderly vol.42, pp.10, 2018, https://doi.org/10.1007/s10916-018-1061-z