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Influences of Wild Haw (Crataegus pinnatifida BUNGE) on Lowering BUN and Creatinine Concentrations in Dyslipidemia

야생 산사(Crataegus pinnatifida BUNGE)가 이상지질혈증의 BUN 및 Creatinine 농도 저하에 미치는 영향

  • Kim, Han-Soo (Department of Food Science & Technology, Pusan National University) ;
  • Kim, Min-A (Department of Food Science & Technology, Pusan National University) ;
  • Duan, Yishan (Department of Food Science & Technology, Pusan National University) ;
  • Jang, Seong-Ho (Department of Bioenviromental Energy, Pusan National University) ;
  • Cho, Han-Jin (Seoul Digital University) ;
  • Ryu, Jae-Young (Department of Urban Enviromental Engineering, Kyungnam University) ;
  • Kim, Sang-Woo (East Sea Fisheries Research Institute, NFRDI)
  • 김한수 (부산대학교 식품공학과) ;
  • 김민아 (부산대학교 식품공학과) ;
  • ;
  • 장성호 (부산대학교 바이오환경에너지학과) ;
  • 조한진 (서울디지털대학교) ;
  • 류재용 (경남대학교 도시환경공학과) ;
  • 김상우 (국립수산과학원 동해수산연구소)
  • Received : 2014.02.10
  • Accepted : 2014.03.27
  • Published : 2014.06.30

Abstract

This study was investigate the influences of wild haw (Crataegus pinnatifida $B_{UNGE}$) on lowering blood urea nitrogen (BUN) and creatinine concentrations in dyslipidemic rats. Four groups of rats were fed different diets for 5 weeks: basal diet (BD group), nondyslipidemic diet+feral haw extract (NDF group), dyslipidemic diet (DLD group), dyslipidemic diet+feral haw extract (DFH group). BUN, creatinine and uric acid concentrations were significantly higher in the DLD group than in the BD group. However, DFH group significantly lowered BUN, creatinine and uric acid concentrations compared to the DLD group. Amylase activity was significantly lower in the DLD group than in the BD group, while DFH group significantly higher compared to the DLD group. Lipase activity was also also significantly lower in the DLD group than the other group. Accordingly, these results suggest that haw extract could be effective for improving kidney function in dyslipidemic rats.

Keywords

References

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