Tuberculosis and Respiratory Diseases

  • 제76권1호
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  • Pages.38-41
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  • 2014
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  • 1738-3536(pISSN)
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  • 2005-6184(eISSN)
대한결핵및호흡기학회 (The Korean Academy of Tuberculosis and Respiratory Diseases)
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A Case of Immunoglobulin G4-Related Disease Presenting as a Pleural Mass

  • Kim, Dong Hyun (Department of Internal Medicine, KEPCO Medical Center) ;
  • Koh, Kyu Han (Department of Internal Medicine, KEPCO Medical Center) ;
  • Oh, Hyeon Sik (Department of Pathology, KEPCO Medical Center) ;
  • Kim, Se Joong (Division of Respiratory and Critical Care Medicine, Seoul National University Bundang Hospital) ;
  • Kang, Sae Han (Department of Internal Medicine, KEPCO Medical Center) ;
  • Jung, Byung Wook (Department of Internal Medicine, KEPCO Medical Center) ;
  • Song, Jun Gyu (Department of Internal Medicine, KEPCO Medical Center) ;
  • Cheon, Mi Ju (Department of Internal Medicine, KEPCO Medical Center) ;
  • Yoon, Seon Bin (Department of Internal Medicine, KEPCO Medical Center) ;
  • Park, Yong Won (Department of Internal Medicine, KEPCO Medical Center) ;
  • Ko, Young Min (Department of Internal Medicine, KEPCO Medical Center) ;
  • Lee, Seung Hyeun (Department of Internal Medicine, KEPCO Medical Center)
  • 투고 : 2013.08.29
  • 심사 : 2013.09.24
  • 발행 : 2014.01.30
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초록

Immunoglobulin G4 (IgG4)-related disease is a newly recognized condition characterized by fibroinflammatory lesions with dense lymphoplasmacytic infiltration, storiform-type fibrosis and obliterative phlebitis. The pathogenesis is not fully understood but multiple immune-mediated mechanisms are believed to contribute. This rare disease can involve various organs and pleural involvement is even rarer. We report a case of IgG4-related disease involving pleura. A 66-year-old man presented with cough and sputum production for a week. Chest radiography revealed consolidation and a pleural mass at right hemithorax. Treatment with antibiotics resolved the consolidation and respiratory symptoms disappeared, but the pleural mass was unchanged. Video-assisted thoracoscopic surgery was performed. Histopathology revealed dense lymphoplasmacytic infiltration and storiform fibrosis with numerous IgG4-bearing plasma cells. The serum IgG4 level was also elevated. Further examination ruled out the involvement of any other organ. The patient was discharged without further treatment and there is no evidence of recurrence to date.

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참고문헌

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피인용 문헌

  1. A Case of IgG4-Related Lung Disease Presenting as Interstitial Lung Disease vol.77, pp.2, 2014, https://doi.org/10.4046/trd.2014.77.2.85
  2. Serosal involvement in IgG4-related disease: report of two cases and review of the literature vol.36, pp.7, 2014, https://doi.org/10.1007/s00296-016-3501-8
  3. IgG4-Related Lung Disease without Elevation of Serum IgG4 Level: A Case Report vol.79, pp.3, 2016, https://doi.org/10.4046/trd.2016.79.3.184
  4. Multiple pleural nodules diagnosed as IgG4-related disease: a case report vol.7, pp.1, 2014, https://doi.org/10.1186/s40792-021-01166-y