Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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A Case on Streptococcal Pneumonia Associated with Leptomeningitis, Osteomyelitis and Epidural Abscess in a Patient with AIDS

  • Jeon, Jae Woong (Division of Infectious Diseases, Department of Internal Medicine, Eulji University Hospital, Eulji University School of Medicine) ;
  • Yoon, Hee Jung (Division of Infectious Diseases, Department of Internal Medicine, Eulji University Hospital, Eulji University School of Medicine) ;
  • Kim, Joo Seok (Division of Infectious Diseases, Department of Internal Medicine, Eulji University Hospital, Eulji University School of Medicine) ;
  • Ryu, Il Hwan (Division of Infectious Diseases, Department of Internal Medicine, Eulji University Hospital, Eulji University School of Medicine) ;
  • Choi, Ji Wook (Division of Infectious Diseases, Department of Internal Medicine, Eulji University Hospital, Eulji University School of Medicine) ;
  • Kim, Min Gyu (Division of Infectious Diseases, Department of Internal Medicine, Eulji University Hospital, Eulji University School of Medicine) ;
  • Na, Young Min (Division of Infectious Diseases, Department of Internal Medicine, Eulji University Hospital, Eulji University School of Medicine) ;
  • Yun, Hyeon Jeong (Division of Infectious Diseases, Department of Internal Medicine, Eulji University Hospital, Eulji University School of Medicine)
  • Received : 2013.08.20
  • Accepted : 2013.09.26
  • Published : 2014.02.28
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Abstract

Patients with acquired immunodeficiency syndrome (AIDS) are at higher risks of bacterial pneumonia than the general population, and the pathogen is the most commonly involved Streptococcus pneumoniae. We hereby report a case of pneumococcal pneumonia associated with leptomeningitis, osteomyelitis and epidural abscess in a patient with AIDS. He is being successfully treated with ampicillin/sulbactam and clindamycin. And because the pneumococcal infection is usually associated with morbidity and mortality rates in the setting of AIDS, we should consider for pneumococcal vaccinations among the AIDS populations.

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References

  1. Kaplan JE, Hanson D, Dworkin MS, Frederick T, Bertolli J, Lindegren ML, et al. Epidemiology of human immunodeficiency virus-associated opportunistic infections in the United States in the era of highly active antiretroviral therapy. Clin Infect Dis 2000;30 Suppl 1:S5-14. https://doi.org/10.1086/313843
  2. Kim JM, Cho GJ, Hong SK, Chung JS, Jang KH, Kim CO, et al. Epidemiologic and clinical features of HIV infection/AIDS in Koreans. Korean J Med 2001;61:355-64.
  3. Holmes CB, Losina E, Walensky RP, Yazdanpanah Y, Freedberg KA. Review of human immunodeficiency virus type 1-related opportunistic infections in sub-Saharan Africa. Clin Infect Dis 2003;36:652-62. https://doi.org/10.1086/367655
  4. Goldman L, Schafer AI. Cecil medicine. 24th ed. Philadelphia: Saunders Elsevier; 2011.
  5. Bhattacharya M, Joshi N. Spinal epidural abscess with myelitis and meningitis caused by Streptococcus pneumoniae in a young child. J Spinal Cord Med 2011;34:340-3. https://doi.org/10.1179/107902610x12883422813507
  6. Lee MS, Woo JH, Kim BN, Kim EO, Kim YS, Ryu JS. A case of Streptococcus pneumoniae infection with AIDS: an autopsy report. Korean J Infect Dis 1996;28:269-75.
  7. Scarborough M, Gordon SB, Whitty CJ, French N, Njalale Y, Chitani A, et al. Corticosteroids for bacterial meningitis in adults in sub-Saharan Africa. N Engl J Med 2007;357:2441-50. https://doi.org/10.1056/NEJMoa065711
  8. Richie MB, Pruitt AA. Spinal cord infections. Neurol Clin 2013;31:19-53. https://doi.org/10.1016/j.ncl.2012.09.006
  9. Pineda C, Vargas A, Rodriguez AV. Imaging of osteomyelitis: current concepts. Infect Dis Clin North Am 2006;20:789-825. https://doi.org/10.1016/j.idc.2006.09.009
  10. Lew DP, Waldvogel FA. Osteomyelitis. Lancet 2004;364:369-79. https://doi.org/10.1016/S0140-6736(04)16727-5
  11. Chidiac C. Pneumococcal infections and adult with risk factors. Med Mal Infect 2012;42:517-24. https://doi.org/10.1016/j.medmal.2012.04.003
  12. Kaplan JE, Benson C, Holmes KK, Brooks JT, Pau A, Masur H, et al. Guidelines for prevention and treatment of opportunistic infections in HIV-infected adults and adolescents: recommendations from CDC, the National Institutes of Health, and the HIV Medicine Association of the Infectious Diseases Society of America. MMWR Recomm Rep 2009;58:1-207.
  13. French N, Gordon SB, Mwalukomo T, White SA, Mwafulirwa G, Longwe H, et al. A trial of a 7-valent pneumococcal conjugate vaccine in HIV-infected adults. N Engl J Med 2010;362:812-22. https://doi.org/10.1056/NEJMoa0903029

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