Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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A Case of Pulmonary Artery Sarcoma Presented as Cavitary Pulmonary Lesions

  • Min, Daniel (Department of Internal Medicine, Bundang CHA Medical Center, CHA University College of Medicine) ;
  • Lee, Ji-Hyun (Department of Internal Medicine, Bundang CHA Medical Center, CHA University College of Medicine) ;
  • Jeong, Hye-Cheol (Department of Internal Medicine, Bundang CHA Medical Center, CHA University College of Medicine) ;
  • Kim, Jung-Hyun (Department of Internal Medicine, Bundang CHA Medical Center, CHA University College of Medicine) ;
  • Shin, Suk-Pyo (Department of Internal Medicine, Bundang CHA Medical Center, CHA University College of Medicine) ;
  • Kim, Hong-Min (Department of Internal Medicine, Bundang CHA Medical Center, CHA University College of Medicine) ;
  • Han, Kyu Hyun (Department of Internal Medicine, Bundang CHA Medical Center, CHA University College of Medicine) ;
  • Jeong, Hye Yun (Department of Internal Medicine, Bundang CHA Medical Center, CHA University College of Medicine) ;
  • Kim, Eun-Kyung (Department of Internal Medicine, Bundang CHA Medical Center, CHA University College of Medicine)
  • Received : 2013.10.14
  • Accepted : 2013.10.23
  • Published : 2014.03.30
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Abstract

Pulmonary artery sarcoma (PAS) is a rare, poorly differentiated malignancy arising from the intimal layer of the pulmonary artery. Contrast-enhanced chest computed tomography (CT) is a good diagnostic modality that shows a low-attenuation filling defect of the pulmonary artery in PAS patients. An 18-year-old man was referred to our hospital for the evaluation and management of cavitary pulmonary lesions that did not respond to treatment. A contrast-enhanced CT of the chest was performed, which showed a filling defect within the right interlobar pulmonary artery. The patient underwent a curative right pneumonectomy after confirmation of PAS. Although lung parenchymal lesions of PAS are generally nonspecific, it can be presented as cavities indicate pulmonary infarcts. Clinicians must consider the possibility of PAS as well as pulmonary thromboembolism in patients with pulmonary infarcts. So, we report the case with PAS that was diagnosed during the evaluation of cavitary pulmonary lesions and reviewed the literatures.

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References

  1. Mandelstamm M. Uber primare Neubildungen des Herzens. Virchows Arch Pathol Anat Physiol Klin Med 1923;245:43-54. https://doi.org/10.1007/BF01992097
  2. Blackmon SH, Rice DC, Correa AM, Mehran R, Putnam JB, Smythe WR, et al. Management of primary pulmonary artery sarcomas. Ann Thorac Surg 2009;87:977-84. https://doi.org/10.1016/j.athoracsur.2008.08.018
  3. Mussot S, Ghigna MR, Mercier O, Fabre D, Fadel E, Le Cesne A, et al. Retrospective institutional study of 31 patients treated for pulmonary artery sarcoma. Eur J Cardiothorac Surg 2013;43:787-93. https://doi.org/10.1093/ejcts/ezs387
  4. Fukuda W, Morohashi S, Fukuda I. Intimal sarcoma of the pulmonary artery: diagnostic challenge. Acta Cardiol 2011;66: 539-41. https://doi.org/10.1080/AC.66.4.2126609
  5. Farooki ZQ, Chang CH, Jackson WL, Clapp SK, Hakimi M, Arciniegas E, et al. Primary pulmonary artery sarcoma in two children. Pediatr Cardiol 1988;9:243-51. https://doi.org/10.1007/BF02078416
  6. Gadkowski LB, Stout JE. Cavitary pulmonary disease. Clin Microbiol Rev 2008;21:305-33. https://doi.org/10.1128/CMR.00060-07
  7. Kim NR, Han J. Pathologic review of cystic and cavitary lung diseases. Korean J Pathol 2012;46:407-14. https://doi.org/10.4132/KoreanJPathol.2012.46.5.407
  8. Delany SG, Doyle TC, Bunton RW, Hung NA, Joblin LU, Taylor DR. Pulmonary artery sarcoma mimicking pulmonary embolism. Chest 1993;103:1631-3. https://doi.org/10.1378/chest.103.5.1631
  9. Mattoo A, Fedullo PF, Kapelanski D, Ilowite JS. Pulmonary artery sarcoma: a case report of surgical cure and 5-year followup. Chest 2002;122:745-7. https://doi.org/10.1378/chest.122.2.745
  10. Ishiguro T, Kasahara K, Matsumoto I, Waseda R, Minato H, Kimura H, et al. Primary pulmonary artery sarcoma detected with a pulmonary infarction. Intern Med 2007;46:601-4. https://doi.org/10.2169/internalmedicine.46.6292
  11. Nagai T, Tabata H, Uehata A. Primary sarcoma of pulmonary artery resembling large pulmonary thrombus: diagnostic utility of different imaging modalities. Eur Heart J 2012;33:2271. https://doi.org/10.1093/eurheartj/ehs069
  12. Ito K, Kubota K, Morooka M, Shida Y, Hasuo K, Endo H, et al. Diagnostic usefulness of 18F-FDG PET/CT in the differentiation of pulmonary artery sarcoma and pulmonary embolism. Ann Nucl Med 2009;23:671-6. https://doi.org/10.1007/s12149-009-0292-y
  13. Anderson MB, Kriett JM, Kapelanski DP, Tarazi R, Jamieson SW. Primary pulmonary artery sarcoma: a report of six cases. Ann Thorac Surg 1995;59:1487-90. https://doi.org/10.1016/0003-4975(95)00149-F
  14. Hoiczyk M, Iliodromitis K, Bauer S, Konorza T, Philipp S, Bankfalvi A, et al. Intimal sarcoma of the pulmonary artery with unusual findings: a case report. Clin Res Cardiol 2012; 101:397-401. https://doi.org/10.1007/s00392-012-0425-5
  15. Jamieson SW. Pulmonary artery sarcoma. Eur J Cardiothorac Surg 2013;43:793-4. https://doi.org/10.1093/ejcts/ezs362

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