YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Antifungal Activities of Essential Oil from the Roots of Angelica dahurica Bentham et Hooker f.

구릿대 뿌리 정유의 항진균 효과

  • Rho, Junghyun (College of Pharmacy, Duksung Women's University) ;
  • Shin, Eunji (College of Pharmacy, Duksung Women's University) ;
  • Shin, Seungwon (College of Pharmacy, Duksung Women's University)
  • 노정현 (덕성여자대학교 약학대학) ;
  • 신은지 (덕성여자대학교 약학대학) ;
  • 신승원 (덕성여자대학교 약학대학)
  • Received : 2014.02.09
  • Accepted : 2014.02.21
  • Published : 2014.02.28
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Abstract

The essential oil was extracted from the roots of Angelica dahurica Bentham et Hooker f. by steam distillation and its composition was analyzed by GC-MS. The antifungal activities were evaluated by micro-dilution method against five Aspergillus and three Trichophyton species. The most abundant component was ${\alpha}$-pinene (17.21%) among 40 compounds identified in this oil. The essential oil fraction of A. dahurica and ${\alpha}$-pinene exhibited marked inhibiting activities against the tested Aspergillus and Trichophyton species with MICs (minimum inhibitory concentrations) between 0.12 mg/ml and 8 mg/ml.

Keywords

References

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