International Journal of Fluid Machinery and Systems

Korean Society for Fluid machinery (한국유체기계학회)
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Flow Evaluation and Hemolysis Analysis of BVAD Centrifugal Blood Pump by Computational Fluids Dynamics

  • Bumrungpetch, Jeerasit (Faculty of Science and Engineering, Queensland University of Technology) ;
  • Tan, Andy Chit (Faculty of Science and Engineering, Queensland University of Technology) ;
  • Liu, Shu-Hong (State Key Laboratory of Hydroscience and Engineering, Tsinghua University) ;
  • Luo, Xian-Wu (State Key Laboratory of Hydroscience and Engineering, Tsinghua University) ;
  • Wu, Qing-Yu (School of Medicine, Tsinghua University) ;
  • Yuan, Jian-Ping (Research Centre of Fluid machinery, Engineering and Technology, Jiangsu University) ;
  • Zhang, Ming-Kui (School of Medicine, Tsinghua University)
  • Received : 2012.07.16
  • Accepted : 2013.02.28
  • Published : 2014.03.31
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Abstract

Computational fluid dynamics (CFD) and particle image velocimetry (PIV) are commonly used techniques to evaluate the flow characteristics in the development stage of blood pumps. CFD technique allows rapid change to pump parameters to optimize the pump performance without having to construct a costly prototype model. These techniques are used in the construction of a bi-ventricular assist device (BVAD) which combines the functions of LVAD and RVAD in a compact unit. The BVAD construction consists of two separate chambers with similar impellers, volutes, inlet and output sections. To achieve the required flow characteristics of an average flow rate of 5 l/min and different pressure heads (left - 100mmHg and right - 20mmHg), the impellers were set at different rotating speeds. From the CFD results, a six-blade impeller design was adopted for the development of the BVAD. It was also observed that the fluid can flow smoothly through the pump with minimum shear stress and area of stagnation which are related to haemolysis and thrombosis. Based on the compatible Reynolds number the flow through the model was calculated for the left and the right pumps. As it was not possible to have both the left and right chambers in the experimental model, the left and right pumps were tested separately.

Keywords

References

  1. Slaughter, M.S., 2010, "Introduction to LVAD Papers," Journal of Cardiac Surgery, Vol. 25, No. 4, pp. 419-420. https://doi.org/10.1111/j.1540-8191.2010.01054.x
  2. Roger, V.L., et al., 2011, "Heart disease and stroke statistics--2011 update: a report from the American Heart Association," Circulation, Vol. 123, No. 4, pp. e18-e209. https://doi.org/10.1161/CIR.0b013e3182009701
  3. Pagani, F.D., et al., 2009, "Extended Mechanical Circulatory Support With a Continuous-Flow Rotary Left Ventricular Assist Device," Journal of the American College of Cardiology, Vol. 54, No. 4, pp. 312-321. https://doi.org/10.1016/j.jacc.2009.03.055
  4. Behbahani, M., et al., 2009, "A review of computational fluid dynamics analysis of blood pumps," European Journal of Applied Mathematics, Vol. 20, No. 04, pp. 363-397. https://doi.org/10.1017/S0956792509007839
  5. May-Newman, K., 2010, "Computational Fluid Dynamics Models of Ventricular Assist Devices", in Computational Cardiovascular Mechanics, J.M. Guccione, G.S. Kassab, and M.B. Ratcliffe, Editors. Springer US. pp. 297-316.
  6. Song, X., et al., 2003, "Computational fluid dynamics prediction of blood damage in a centrifugal pump," Artificial organs, Vol. 27, No. 10, pp. 938-941. https://doi.org/10.1046/j.1525-1594.2003.00026.x
  7. Song, X., et al., 2004, "Quantitative Evaluation of Blood Damage in a Centrifugal VAD by Computational Fluid Dynamics," Journal of Fluids Engineering, Vol. 126, No. 3, pp. 410-418. https://doi.org/10.1115/1.1758259
  8. Day, S.W., et al., 2001, "Particle Image Velocimetry Measurements of Blood Velocity in a Continuous Flow Ventricular Assist Device," ASAIO Journal, Vol. 47, No. 4, pp. 406-411. https://doi.org/10.1097/00002480-200107000-00021
  9. Zhang, J., et al., 2006, "Computational and Experimental Evaluation of the Fluid Dynamics and Hemocompatibility of the CentriMag Blood Pump," Artificial Organs, Vol. 30, No. 3, pp. 168-177. https://doi.org/10.1111/j.1525-1594.2006.00203.x
  10. Day, S.W., et al., 2002, "A Prototype HeartQuest Ventricular Assist Device for Particle Image Velocimetry Measurements," Artificial Organs, Vol. 26, No. 11, pp. 1002-1005. https://doi.org/10.1046/j.1525-1594.2002.07124.x
  11. Garon, A. and M.-I. Farinas, 2004, "Fast Three-dimensional Numerical Hemolysis Approximation," Artificial Organs, Vol. 28, No. 11, pp. 1016-1025. https://doi.org/10.1111/j.1525-1594.2004.00026.x
  12. Medvitz, R.B., et al., 2011, "Computational Fluid Dynamics Design and Analysis of a Passively Suspended Tesla Pump Left Ventricular Assist Device," Artificial Organs, Vol. 35, No. 5, pp. 522-533. https://doi.org/10.1111/j.1525-1594.2010.01087.x
  13. Nose, Y., 1998, "Design and Development Strategy for the Rotary Blood Pump," Artificial Organs, Vol. 22, No. 6, pp. 438-446. https://doi.org/10.1046/j.1525-1594.1998.06098.x

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