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Sires' MC1R Genotypes and Coat Color of the Offspring of the Chikso (Korean Brindle Cattle)

칡소 씨수소의 MC1R 유전자형과 자손의 모색 발현

  • Park, Jae-Hee (Department of Animal Sciences and Institute of Rare Earth for Biological Application, College of Agriculture and Life Science, Chonbuk National University) ;
  • Lee, Chang-Woo (Gangwon Province Livestock Research Center) ;
  • Lee, Hae-Lee (Livestock Experiment Station, Jeollabuk-do Institute of Livestock and Veterinary Research) ;
  • Choi, Jae Won (Institute of Livestock and Veterinary Research) ;
  • Choy, Yun Ho (Animal Genetics and Breeding Division, Department of Animal Resources Development, NIAS, RDA) ;
  • Kwon, A-Nam (Department of Animal Sciences and Institute of Rare Earth for Biological Application, College of Agriculture and Life Science, Chonbuk National University) ;
  • Ji, Yeoen Hee (Department of Animal Sciences and Institute of Rare Earth for Biological Application, College of Agriculture and Life Science, Chonbuk National University) ;
  • Kim, Jong Gug (Department of Animal Sciences and Institute of Rare Earth for Biological Application, College of Agriculture and Life Science, Chonbuk National University)
  • 박재희 (전북대학교 동물자원과학과/희토생물응용연구소) ;
  • 이창우 (강원도 축산기술연구센터) ;
  • 이해이 (전라북도 축산위생연구소 축산시험장) ;
  • 최재원 (충청북도 축산위생연구소) ;
  • 최연호 (국립축산과학원 가축개량평가과) ;
  • 권아남 (전북대학교 동물자원과학과/희토생물응용연구소) ;
  • 지연희 (전북대학교 동물자원과학과/희토생물응용연구소) ;
  • 김종국 (전북대학교 동물자원과학과/희토생물응용연구소)
  • Received : 2014.01.07
  • Accepted : 2014.03.24
  • Published : 2014.03.31

Abstract

The objective of this study was to determine the effect of the MC1R genotypes of the Chikso (Korean brindle cattle) sires on the coat colors of their offspring. In this study, 15 Chikso sires with known MC1R genotypes were used for breeding in the Gangwon Province Livestock Research Center, the Chungbuk Institute of Livestock and Veterinary Research, and the Livestock Experiment Station, Jeonbuk Institute of Livestock and Veterinary Research from either 2011 or 2012 to 2013. There were 6 sires with $E^+E^+$ genotypes and 9 sires with $E^+e$ genotypes, and their coat colors were all whole brindle (more than 50 of the body). Among the 90 calves produced in 2011~2013 or 2012~2013 from the 15 sires, 50 (55.6%) of them were females and 40 (44.4%) of them were males. Coat colors of the offspring were determined when they reached over 6 months of age. Calves with whole brindle, part brindle, brown and black coat colors were 42 (48.3%), 11 (12.6%), 18 (20.7%) and 16 (18.4%), respectively. Ratio of calves with whole brindle coat color was higher than any other coat colors. Among the offspring with whole brindle color, 20 (41.7%) calves were female and 22 (51.3%) calves were male. By determining the MC1R genotypes of the dams and calves in this study along the family lines, and investigating other genes that may be involved in the coat colors of the Chikso, better breeding system may be established to increase the brindle coat color appearance in the future.

Keywords

References

  1. Barsh GS. 1996. The genetics of pigmentation: From fancy genes to complex traits. Trends Genet. 12(8): 299-305. https://doi.org/10.1016/0168-9525(96)10031-7
  2. Berryers TG, Schmutz SM, Schimpf RJ, Cowan CM and Potter J. 2003. TYRP1 is associated with dun coat colour in Dexter Cattle or how now brown cow? Anim. Genet. 34: 169-175. https://doi.org/10.1046/j.1365-2052.2003.00985.x
  3. Brenig B, Beck J, Floren C, Bornemann-Kolatzki K, Wiedemann I, Hennecke S, Swalve H and Schutz E. 2013. Molecular genetics of coat colour variations in White Galloway and White Park cattle. Anim. Genet. 44(4):450-3. https://doi.org/10.1111/age.12029
  4. Cone RD, Lu D, Koppula S, Vage DI, Klungland K, Boston B, Chen W, Orth DN, Pouton C and Kesterson RA. 1996. The melanocortin receptors : agonists, antagonists, and the hormonal control of pigmentation. Recent Prog. Horm. Res. 51: 287-317.
  5. Gan HY, Li JB, Wang HM, Gao YD, Liu WH, Li JP and Zhong JF. 2007. Allele frequencies of TYR and MC1R in Chinese native cattle. Anim. Sci. J. 78: 484-488. https://doi.org/10.1111/j.1740-0929.2007.00466.x
  6. Han SH, Cho IC, Kim JH, Ko MS, Kim YH, Kim EY, Park SP, and Lee SS. 2011. Coat color patterns and genotypes of extension and Agouti in Hanwoo and Jeju Black cattle. J. Life Sci. 494-501.
  7. Klungland H, Vage DI, Gomez-Raya L, Adalsteinsson S and Lien S. 1995. The role of melanocyte-stimulating hormone (MSH) receptor in bovine coat color determination. Mamm. Genome 6: 636-639. https://doi.org/10.1007/BF00352371
  8. Rouzaud F, Martin J, Gallet PF, Delourme D, Goulemot-Leger V, Amigues Y, Menissier F, Leveziel H, Julien R and Oulmouden A. 2000. A first genotyping assay of French cattle breeds based on a new allele of the extension gene encoding the melanocortin-1 receptor (MC1R). Genet. Sel. Evol. 32 (5):511-520. https://doi.org/10.1186/1297-9686-32-5-511
  9. Sasazaki S, Usui M, Mannen H, Hiura C and Tsuji S. 2005. Allele frequencies of the extension locus encoding the melanocortin 1 receptor in Japanese and Korean cattle. Anim. Sci. J. 76(2): 129-132. https://doi.org/10.1111/j.1740-0929.2005.00247.x
  10. Schmutz SM and Dreger DL. 2013. Interaction of MC1R and PMEL alleles on solid coat colors in Highland cattle. Anim. Genet. 44(1): 9-13. https://doi.org/10.1111/j.1365-2052.2012.02361.x
  11. Seo KS, Mohanty TR, Choi T and Hwang IH. 2007. Biology of epidermal and hair pigmentation in cattle: a minireview. Vet. Dermatol. 18: 392-400. https://doi.org/10.1111/j.1365-3164.2007.00634.x
  12. Vage DI, Klungland H, Lu D and Cone RD. 1999. Molecular and pharmacological characterization of dominant black coat color in sheep. Mamm. Genome 10: 39-43. https://doi.org/10.1007/s003359900939
  13. 김상환, 정경섭, 이호준, 백준석, 정덕원, 김대은, 윤종택. 2013. 칡소의 MC1R의 유전자형에 따른 교배 조합이 자손의 모색과 유전자형 변이에 미치는 영향. J. Emb. Trans. 28(3): 215-222. https://doi.org/10.12750/JET.2013.28.3.215
  14. 김태헌, 윤두학, 박응우, 이혜영, 오성종, 정일정, 탁태영, 김경남, 한재용. 2000. 소 품종별 melanocortin receptor 1(MC1R) 유전자의 유전자형 빈도에 관한 연구. J. Anim. Sci. & Technol. 42(6): 735-744.
  15. 도경탁, 신희영, 이종혁, 김내수, 박응우, 윤두학, 김관석. 2007. 한우에서 모색 관련 유전자 변이에 관한 연구. J. Anim. Sci. & Technol. 49(6): 711-718. https://doi.org/10.5187/JAST.2007.49.6.711
  16. 박재희, 이해이, 김용수, 김종국. 2012. MC1R 유전자형의 유전자형과 칡소의 모색 발현 및 비경색 분포에 관한 연구. J. Anim. Sci. & Technol. 54(4): 255-265. https://doi.org/10.5187/JAST.2012.54.4.255
  17. 이성수, 양영훈, 강승률, 오운용, 양보석, 고서봉, 오성종, 김규일. 2000. 한우, 제주재래흑우, 흑모화우와 갈모화우에서의 MSH receptor(MC1R) 유전자의 유전자형 및 빈도비교. J. Anim. Sci. & Technol. 42(3): 253-260.
  18. 이성수, 양보석, 양영훈, 강승률, 고서봉, 정친관, 오운용, 오성종, 김규일. 2002. 칡소와 비경 흑색 한우의 melanocortin receptor 1(MC1R) 유전자형 분석. J. Anim. Sci. & Technol. 44(1): 23-30. https://doi.org/10.5187/JAST.2002.44.1.023
  19. 이승미, 이우원, 이강록, 이동수. 2009. PCR-RFLP 법과 allelespecific PCR법을 이용한 한우고기 판별연구. The annual report of Busan Metropolitan City Institute of Health & Environment 19(1): 88-93.
  20. 이호준, 김상환, 이경택, 윤종택. 2011. 수정란 이식에 의해 생산된 칡소의 모색발현. J. Life Sci. 15(4):325-329.
  21. 정의룡, 김우태, 김연수, 한상기. 2000. 소 모색관련 유전자 MC1R의 PCR-RFLP Marker를 이용한 한우육 판별. J. Anim. Sci. & Technol. 42(4): 379-390.
  22. 진실, 심정미, 서동원, 정우영, 류승희, 김진호, 이준헌. 2011. 한우 후보씨수소 및 칡소와 흑소에서 MC1R 유전자의 유전자형 분석. CNU J. Agri. Sci. 38(3):453-458.
  23. 한국종축개량협회. 2008. 한우기준공고(공고 2008-2호).