한국발생생물학회지:발생과생식 (Development and Reproduction)

  • 제18권1호
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  • Pages.57-64
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  • 2014
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  • 2465-9525(pISSN)
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  • 2465-9541(eISSN)
한국발생생물학회 (The Korean Society of Developmental Biology)
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The Potential Regressive Role of Syzygium aromaticum on the Reproduction of Male Golden Hamsters

  • Choi, Donchan (Department of Life Science, College of Environmental Sciences, Yong-In University) ;
  • Roh, Hyun Soo (Department of Life Science, College of Environmental Sciences, Yong-In University) ;
  • Kang, Dong Won (Department of Life Science, College of Environmental Sciences, Yong-In University) ;
  • Lee, Jong Seok (Department of Life Science, College of Environmental Sciences, Yong-In University)
  • 투고 : 2014.01.15
  • 심사 : 2014.02.10
  • 발행 : 2014.03.31
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초록

The flower buds of Syzygium aromaticum (clove) have been used as traditional medicine for the treatment of male sexual disorders in Asian countries. Recently, there are some reports about the effects of the clove on reproductive activities in mammals. Therefore, its effect on testicular function was examined in male golden hamsters whose reproductive activity is inhibited by photoperiod such as winter climate. The male animals were given by daily oral administrations (56 consecutive days) in three doses (4 mg, 20 mg, and 100 mg/kg BW) of the alcoholic extract of the clove. Generally lower dose (4 mg) of the extract continued to keep the reproductive activities of testes. The both middle and high doses (20 mg and 100 mg) of the extract completely inhibited the testicular activity in some animals. Taken together, these results suggest a possible biphasic action of alcoholic extract of Syzygium aromaticum flower bud on testicular function.

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참고문헌

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