DOI QR코드

DOI QR Code

Identification of Knowledge Gaps Regarding Healthcare Workers' Exposure to Antineoplastic Drugs: Review of Literature, North America versus Europe

  • Hon, Chun-Yip (School of Occupational and Public Health, Ryerson University) ;
  • Barzan, Cris (School of Population and Public Health, University of British Columbia) ;
  • Astrakianakis, George (School of Population and Public Health, University of British Columbia)
  • 투고 : 2014.04.16
  • 심사 : 2014.06.02
  • 발행 : 2014.12.30

초록

We have been examining the issue of healthcare workers' exposure to antineoplastic drugs for nearly a decade and have observed that there appears to be more publications on the subject matter originating from Europe than from North America. The concern is that findings from Europe may not be generalizable to North America because of differences in handling practices, regulatory requirements, and training. Our objective was to perform a literature review to confirm our observation and, in turn, identify gaps in knowledge that warrants addressing in North America. Using select keywords, we searched for publications in PubMed and Web of Science. All papers were initially classified according to the originating continent and then categorized into one or more subject categories (analytical methods, biological monitoring, occupational exposure, surface contamination, and probability of risk/exposure). Our review identified 16 papers originating from North America and 55 papers from Europe with surface contamination being the subject matter most often studied overall. Based on our results, we are of the opinion that North American researchers need to further conduct dermal and/or urinary drug contamination studies as well as assess the exposure risk faced by healthcare workers who handle antineoplastic drugs. Trends in exposure levels should also be explored.

키워드

피인용 문헌

  1. Antineoplastic drug contamination in the urine of Canadian healthcare workers vol.88, pp.7, 2015, https://doi.org/10.1007/s00420-015-1026-1
  2. A review of surface wipe sampling compared to biologic monitoring for occupational exposure to antineoplastic drugs vol.14, pp.3, 2014, https://doi.org/10.1080/15459624.2016.1237026
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  6. Extent of Primary DNA Damage Measured by the Comet Assay in Health Professionals Exposed to Antineoplastic Drugs: A Systematic Review and Meta-Analysis vol.17, pp.2, 2014, https://doi.org/10.3390/ijerph17020523
  7. Spatial and Temporal Variability in Antineoplastic Drug Surface Contamination in Cancer Care Centers in Alberta and Minnesota vol.65, pp.7, 2014, https://doi.org/10.1093/annweh/wxab013