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DOI QR Code

Clinical features of elderly chronic urticaria

  • Ban, Ga-Young (Department of Allergy and Clinical Immunology, Ajou University School of Medicine) ;
  • Kim, Mi-Yea (Department of Allergy and Clinical Immunology, Ajou University School of Medicine) ;
  • Yoo, Hye-Soo (Department of Allergy and Clinical Immunology, Ajou University School of Medicine) ;
  • Nahm, Dong-Ho (Department of Allergy and Clinical Immunology, Ajou University School of Medicine) ;
  • Ye, Young-Min (Department of Allergy and Clinical Immunology, Ajou University School of Medicine) ;
  • Shin, Yoo-Seob (Department of Allergy and Clinical Immunology, Ajou University School of Medicine) ;
  • Park, Hae-Sim (Department of Allergy and Clinical Immunology, Ajou University School of Medicine)
  • 투고 : 2013.12.13
  • 심사 : 2014.07.28
  • 발행 : 2014.11.01

초록

Background/Aims: Chronic urticaria (CU) is defined as itchy wheals lasting 6 weeks or more. As the aged population increases worldwide, it is essential to identify the specific features of this disease in the elderly population. Methods: We investigated the prevalence and clinical features of CU in elderly patients. Medical records of 837 CU patients from the outpatient Allergy Clinic of Ajou University Hospital, Korea were analyzed retrospectively. Patients with chronic spontaneous urticaria according to the EAACI/$GA^2LEN$/EDF/WAO guidelines were included. Patients older than 60 years were defined as elderly. Results: Of the 837 patients, 37 (4.5%) were elderly. In elderly versus nonelderly CU patients, the prevalence of atopic dermatitis (AD) was significantly higher (37.8% vs. 21.7%, respectively; p = 0.022), while that of aspirin intolerance was lower (18.9% vs. 43.6%, respectively; p = 0.003) in terms of comorbid conditions. The prevalences of serum specific immunoglobulin E antibodies to staphylococcal enterotoxin A and staphylococcal enterotoxin B were considerably higher in elderly CU patients with AD than in those without AD (37.5% vs. 0%, respectively). Conclusions: Elderly patients with CU had a higher prevalence of AD. Therefore, there is a need to recognize the existence of AD in elderly CU patients.

키워드

과제정보

연구 과제 주관 기관 : Korea Health Industry Development Institute (KHIDI)

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피인용 문헌

  1. Allergic diseases in the elderly: biological characteristics and main immunological and non-immunological mechanisms vol.15, pp.None, 2014, https://doi.org/10.1186/s12948-017-0059-2
  2. Natural History of Chronic Urticaria in Korea vol.32, pp.1, 2020, https://doi.org/10.5021/ad.2020.32.1.38
  3. Prevalence of Chronic Inducible Urticaria in Elderly Patients vol.10, pp.2, 2014, https://doi.org/10.3390/jcm10020247
  4. Managing Chronic Urticaria and Recurrent Angioedema Differently with Advancing Age vol.9, pp.6, 2014, https://doi.org/10.1016/j.jaip.2021.03.034