Korean Journal of Veterinary Research (대한수의학회지)

The Korean Society of Veterinary Science (대한수의학회)
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Myxoid liposarcoma in a dog

개에서의 myxoid liposarcoma 증례 보고

  • Jeon, Sung-Joo (College of Veterinary Medicine, Chungnam National University) ;
  • Cho, Eun-Sang (College of Veterinary Medicine, Chungnam National University) ;
  • Noh, Hye-Jin (College of Veterinary Medicine, Chungnam National University) ;
  • Son, Hwa-Young (College of Veterinary Medicine, Chungnam National University)
  • 전성주 (충남대학교 수의과대학) ;
  • 조은상 (충남대학교 수의과대학) ;
  • 노혜진 (충남대학교 수의과대학) ;
  • 손화영 (충남대학교 수의과대학)
  • Received : 2013.03.27
  • Accepted : 2014.01.07
  • Published : 2014.03.31
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Abstract

The pathological features of a mass in the back skin region of an 8-year-old castrated male dog are described herein. The cut section of the tumor was white to tan with a soft multilobulated mass containing hemorrhagic and necrotic foci and a mucinous-like composition. Microscopically, the tumor was composed of a mixture of lipocytes, lipoblasts, spindle cells and stellate cells and had a myxoid background. Oil red O staining revealed that the cytoplasm of neoplastic cells contained large numbers of lipid droplets. Immunohistochemically, tumor cells were positive for vimentin and S-100 protein. The skin mass was diagnosed as myxoid liposarcoma.

Keywords

References

  1. Andreasen CB, Mahaffey EA, Duncan JR. Intermediate filament staining in the cytologic and histologic diagnosis of canine skin and soft tissue tumors. Vet Pathol 1988, 25, 343-349. https://doi.org/10.1177/030098588802500502
  2. Baez JL, Hendrick MJ, Shofer FS, Goldkamp C, Sorenmo KU. Liposarcomas in dogs: 56 cases (1989-2000). J Am Vet Med Assoc 2004, 224, 887-891. https://doi.org/10.2460/javma.2004.224.887
  3. Cheng J, Yu H, Wang L, Wang X, Shen G. Primary oral and maxillofacial liposarcoma: a clinicopathological and immunohistochemical study of eleven cases. Arch Med Sci 2012, 8, 316-323.
  4. Daugaard S. Current soft-tissue sarcoma classifications. Eur J Cancer 2004, 40, 543-548. https://doi.org/10.1016/j.ejca.2003.11.009
  5. Dei Tos AP, Wadden C, Fletcher CDM. S-100 protein staining in liposarcoma: its diagnostic utility in the high-grade myxoid (round cell) variant. Appl Immunohistochem 1996, 4, 95-101.
  6. Doster AR, Tomlinson MJ, Mahaffey EA, Jordan CW. Canine liposarcoma. Vet Pathol 1986, 23, 84-87. https://doi.org/10.1177/030098588602300117
  7. Fletcher CDM, Unni KK, Mertens F. Pathology and Genetics of Tumours of Soft Tissue and Bone. pp. 12-40, IARC Press, Lyon, 2002.
  8. Ganesh IM, Subramani D, Halagowder D. Mucin glycoarray in gastric and gallbladder epithelia. J Carcinog 2007, 6, 10. https://doi.org/10.1186/1477-3163-6-10
  9. Goldschmidt MH, Hendrick MJ. Tumors of the Skin and Soft Tissues: Liposarcoma. In : Meuten DJ (ed.). Tumors in Domestic Animals. 4th ed. pp. 97-99, Iowa State Press, 2002.
  10. Graadt van Roggen JF, Hogendoorn PCW, Fletcher CDM. Myxoid tumours of soft tissue. Histopathology 1999, 35, 291-312. https://doi.org/10.1046/j.1365-2559.1999.00835.x
  11. Hargis AM, Ginn PE. The integument. In: McGavin MD, Zachary JF (ed.). Pathologic Basis of Veterinary Disease, 4th ed. pp. 1146-1147, Mosby, St. Louis, 2007.
  12. Kaneko JJ, Harvey JW, Bruss ML. Clinical Biochemistry of Domestic Animals. 6th ed. pp. 768-771, Academic Press, San Diego, 2008.
  13. Kwon HJ, Park MS, Kim DY, Cho DY, Yoon BI, Shin NS, Kim DY. Round cell variant of myxoid liposarcoma in a Japanese Macaque (Macaca fuscata). Vet Pathol 2007, 44, 229-232. https://doi.org/10.1354/vp.44-2-229
  14. Masserdotti C, Bonfanti U, De Lorenzi D, Ottolini N. Use of oil red O stain in the cytologic diagnosis of canine liposarcoma. Vet Clin Pathol 2006, 35, 37-41. https://doi.org/10.1111/j.1939-165X.2006.tb00086.x
  15. Messick JB, Radin MJ. Cytologic, histologic, and ultrastructural characteristics of a canine myxoid liposarcoma. Vet Pathol 1989, 26, 520-522. https://doi.org/10.1177/030098588902600612
  16. Nemanqani D, Mourad WA. Cytomorphologic features of fine-needle aspiration of liposarcoma. Diagn Cytopathol 1999, 20, 67-69. https://doi.org/10.1002/(SICI)1097-0339(199902)20:2<67::AID-DC4>3.0.CO;2-D
  17. Rabanal RH, Fondevila DM, Montane V, Domingo M, Ferrer L. Immunocytochemical diagnosis of skin tumours of the dog with special reference to undifferentiated types. Res Vet Sci 1989, 47, 129-133.
  18. Shmitt FC, Bacchi CE. S-100 protein: is it useful as a tumour marker in diagnostic immunocytohemistry? Histopathol 1989, 15, 281-288. https://doi.org/10.1111/j.1365-2559.1989.tb03078.x
  19. Shanley KJ, Miller WH Jr. Panniculitis in the dog: a report of five cases. J Am Anim Hosp Assoc 1985, 21, 545-550.
  20. Weiss SW, Goldblum JR. Liposarcoma. In: Enzinger and Weiss's Soft Tissue Tumors. 4th ed. pp. 641-693, Mosby, St. Louis, 2001.