The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
권호 표지
DOI QR코드

DOI QR Code

A Case of Lupus Pneumonitis Therapy in a Patient with Acute Systemic Lupus Erythematosus

전신 홍반 루푸스 환자에게 발생한 급성 루푸스 폐렴 치료 1예

  • Jung, Se Young (Department of Internal Medicine, Anyang SAM Hospital) ;
  • Park, Hyun Sung (Department of Internal Medicine, Anyang SAM Hospital) ;
  • Kang, Shin Myung (Department of Internal Medicine, Anyang SAM Hospital) ;
  • Lee, Sung Hak (Department of Internal Medicine, Anyang SAM Hospital) ;
  • Park, Pyung Kang (Department of Internal Medicine, Anyang SAM Hospital) ;
  • Jung, Ki Hwan (Department of Internal Medicine, Anyang SAM Hospital) ;
  • Oh, Ji-Min (Department of Internal Medicine, Anyang SAM Hospital)
  • Received : 2014.01.11
  • Accepted : 2014.04.24
  • Published : 2014.11.01
⟨ Previous Next ⟩

Abstract

Systemic lupus erythematosus is a connective tissue disease with multiple organ involvement due to atypical creation of an antibody to an intracellular component. Although it can directly invade respiratory organs, such as the pleura, pulmonary parenchyma, trachea, pulmonary vessels, and pulmonary muscle, pulmonary involvement is mostly secondary to infection after immunosuppressant use, and pulmonary parenchyma invasion due to an immune response is relatively rare. This is a case report of acute lupus pneumonitis in a patient with systemic lupus erythematosus who was successfully treated with steroid therapy.

전신 홍반 루푸스로 치료를 받고 있는 환자에서 갑작스런 발열과 호흡 곤란이 있었고, 혈액, 객담 배양 검사 등을 통해 감염을 배제하고 루푸스 폐렴으로 진단할 수 있었으며 스테로이드와 보존적 치료로 호전 후 관해를 유지하여 이를 보고한다.

Keywords

References

  1. Haupt HM, Moore GW, Hutchins GM. The lung in systemic lupus erythematosus. Analysis of the pathologic changes in 120 patients. Am J Med 1981;71:791-798. https://doi.org/10.1016/0002-9343(81)90366-1
  2. Quadrelli SA, Alvarez C, Arce SC, et al. Pulmonary involvement of systemic lupus erythematosus: analysis of 90 necropsies. Lupus 2009;18:1053-1060. https://doi.org/10.1177/0961203309106601
  3. Matthay RA, Schwarz MI, Petty TL, et al. Pulmonary manifestations of systemic lupus erythematosus: review of twelve cases of acute lupus pneumonitis. Medicine (Baltimore) 1975;54:397-409. https://doi.org/10.1097/00005792-197509000-00003
  4. Wang DY, Yang PC, Yu WL, Kuo SH, Hsu NY. Serial antinuclear Antibodies titre in pleural and pericardial fluid. Eur Respir J 2000;15:1106-1110. https://doi.org/10.1034/j.1399-3003.2000.01520.x
  5. Cheema GS, Quismorio FP Jr. Interstitial lung disease in systemic lupus erythematosus. Curr Opin Pulm Med 2000;6:424-429. https://doi.org/10.1097/00063198-200009000-00007
  6. Kim JS, Lee KS, Koh EM, Kim SY, Chung MP, Han J. Thoracic involvement of systemic lupus erythematosus: clinical, pathologic, and radiologic findings. J Comput Assist Tomogr 2000;24:9-18. https://doi.org/10.1097/00004728-200001000-00003
  7. Pego-Reigosa JM, Medeiros DA, Isenberg DA. Respiratory manifestations of systemic lupus erythematosus: old and new concepts. Best Pract Res Clin Rheumatol 2009;23:469-480. https://doi.org/10.1016/j.berh.2009.01.002
  8. Kamen DL, Strange C. Pulmonary manifestations of systemic lupus erythematosus. Clin Chest Med 2010;31: 479-488. https://doi.org/10.1016/j.ccm.2010.05.001
  9. Santos-Ocampo AS, Mandell BF, Fessler BJ. Alveolar hemorrhage in systemic lupus erythematosus: presentation and management. Chest 2000;118:1083-1090. https://doi.org/10.1378/chest.118.4.1083
  10. Witt C, Dorner T, Hiepe F, Borges AC, Fietze I, Baumann G. Diagnosis of alveolitis in interstitial lung manifestation in connective tissue diseases: importance of late inspiratory crackles, 67 gallium scan and bronchoalveolar lavage. Lupus 1996;5:606-612. https://doi.org/10.1177/096120339600500609