The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
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Polycythemia Vera Presenting with Generalized Chorea: A Case Report and Review of the Literature

무도병을 주소로 내원한 진성적혈구증가증 1예

  • Kim, Sun Woong (Department of Internal Medicine, Medicine, Konkuk University Medical Center, Konkuk University School of Medicine) ;
  • Yu, Hyung Min (Department of Internal Medicine, Medicine, Konkuk University Medical Center, Konkuk University School of Medicine) ;
  • Lee, Yoon Jeong (Department of Internal Medicine, Medicine, Konkuk University Medical Center, Konkuk University School of Medicine) ;
  • Kim, Hee Jin (Department of Neurology, Medicine, Konkuk University Medical Center, Konkuk University School of Medicine) ;
  • Hur, Mina (Department of Laboratoy Medicine, Konkuk University Medical Center, Konkuk University School of Medicine) ;
  • Lee, Hong Ghi (Department of Internal Medicine, Medicine, Konkuk University Medical Center, Konkuk University School of Medicine)
  • 김선웅 (건국대학교 의학전문대학원 건국대학교병원 내과) ;
  • 유형민 (건국대학교 의학전문대학원 건국대학교병원 내과) ;
  • 이윤정 (건국대학교 의학전문대학원 건국대학교병원 내과) ;
  • 김희진 (건국대학교 의학전문대학원 건국대학교병원 신경과) ;
  • 허미나 (건국대학교 의학전문대학원 건국대학교병원 진단검사의학과) ;
  • 이홍기 (건국대학교 의학전문대학원 건국대학교병원 내과)
  • Received : 2013.10.16
  • Accepted : 2014.01.15
  • Published : 2014.11.01
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Abstract

Polycythemia vera (PV) is a myeloproliferative neoplasm characterized by erythrocytosis. Clinical symptoms can range in severity from headache and tinnitus to thrombohemorrhagic complications. Neurologic symptoms are common at the onset of polycythemia; however, chorea due to PV is a rare complication. We present the case of a 77-year-old female who was referred to our hospital because of choreic movement of the limbs, head and face. She was diagnosed with JAK2V617F mutation-positive PV. Her chorea was completely resolved by phlebotomy combined with hydroxyurea and aspirin.

Keywords

References

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Cited by

  1. Generalized Chorea Due to Secondary Polycythemia Responding to Phlebotomy vol.14, pp.1, 2021, https://doi.org/10.14802/jmd.20081