The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
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A Case of Ticagrelor Rescue Therapy in a Patient with Subacute Stent Thrombosis

아급성 관상동맥 스텐트 혈전증에서 Ticagrelor를 사용한 1예

  • Ko, Jun Kwon (Departments of Internal Medicine, Hanyang University College of Medicine) ;
  • Kim, Ji Soong (Departments of Internal Medicine, Hanyang University College of Medicine) ;
  • Chung, Sung Jun (Departments of Internal Medicine, Hanyang University College of Medicine) ;
  • Kim, Seong Jong (Departments of Internal Medicine, Hanyang University College of Medicine) ;
  • Kim, Byung Sihk (Departments of Internal Medicine, Hanyang University College of Medicine) ;
  • Kim, You Shin (Departments of Internal Medicine, Hanyang University College of Medicine) ;
  • Shin, Jeong Hun (Departments of Internal Medicine, Hanyang University College of Medicine)
  • 고준권 (한양대학교 의과대학 내과학교실) ;
  • 김지숭 (한양대학교 의과대학 내과학교실) ;
  • 정승준 (한양대학교 의과대학 내과학교실) ;
  • 김성종 (한양대학교 의과대학 내과학교실) ;
  • 김병식 (한양대학교 의과대학 내과학교실) ;
  • 김유신 (한양대학교 의과대학 내과학교실) ;
  • 신정훈 (한양대학교 의과대학 내과학교실)
  • Received : 2014.10.13
  • Accepted : 2014.02.24
  • Published : 2014.11.01
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Abstract

Stent thrombosis (ST) is a rare but catastrophic complication of a drug-eluting stent. Although dual antiplatelet therapy with aspirin and clopidogrel significantly reduces the occurrence of ST, it continues to occur and is occasionally associated with clopidogrel resistance. Here, we describe a 71-yr-old man with subacute stent thrombosis and clopidogrel resistance following drug-eluting stent implantation who underwent successful ticagrelor rescue therapy.

뇌졸중으로 아스피린과 클로피도그렐을 복용하던 71세 남자 환자에서 급성 하벽 심근경색증으로 관상동맥 중재술을 시행하였다. 시술 7일째 급성 호흡곤란 및 ST분절 상승소견으로 시행한 관상동맥 조영술에서 스텐트 혈전증을 진단 후 중재술을 시행하였다. 혈소판 기능 검사에서 Clopidogrel 저항성이 확인하였고 뇌졸중 과거력을 고려해 Ticagrelor로 구조요법(rescue therapy)을 시행한 증례를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

Keywords

References

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