The Korean Journal of Medicine

  • 제87권4호
  • /
  • Pages.395-400
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  • 2014
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  • 1738-9364(pISSN)
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  • 2289-0769(eISSN)
대한내과학회 (The Korean Association of Internal Medicine)
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전신경화증의 새로운 분류기준

Updated Classification Criteria for Systemic Sclerosis: the Concept of Early Diagnosis

  • 김현숙 (순천향대학교 의과대학 순천향대학교 서울병원 류마티스내과)
  • Kim, Hyun-Sook (Division of Rheumatology, Department of Internal Medicine, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine)
  • 발행 : 2014.10.01
⟨ 이전 논문 다음 논문 ⟩

초록

Systemic sclerosis (SSc) is a connective tissue disease of unknown origin, which is characterized by fibrosis of the skin and internal organs, and endothelial and immunologic dysfunction. The presence of a wide range of symptoms renders disease classification difficult. Although recent studies have contributed to our understanding of this debilitating illness, well-validated classification criteria are required for accurate comparison between registries and clinical trials, to assess response to treatment, morbidity and prognosis. Given the emphasis placed upon early and aggressive treatment, the 1980 American College of Rheumatology (ACR) classification criteria are of limited utility with respect to early diagnosis of SSc and limited cutaneous SSc. Recently, the 2013 ACR/European League Against Rheumatism classification criteria for SSc were published for research and clinical practice purposes. These criteria include skin thickening, fingertip lesions, telangiectasia, abnormal nailfold capillaries, Raynaud's phenomenon, SSc-specific autoantibodies and pulmonary complications pertaining to vasculopathy, autoimmunity and fibrosis. These updated criteria should allow a greater number of patients to receive an early diagnosis of SSc.

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참고문헌

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피인용 문헌

  1. The Efficacy of Nailfold Capillaroscopy in Patients with Raynaud's Phenomenon vol.22, pp.2, 2014, https://doi.org/10.4078/jrd.2015.22.2.69
  2. The Clinical Efficacy of Nailfold Capillaroscopy in Rheumatic Diseases vol.90, pp.6, 2014, https://doi.org/10.3904/kjm.2016.90.6.494
  3. 전신경화증으로 유발된 속발성 레이노증후군 호전 1례 vol.31, pp.4, 2014, https://doi.org/10.6114/jkood.2018.31.4.108
  4. 근골격계 질환에서 진단의학검사의 활용 vol.13, pp.2, 2018, https://doi.org/10.30581/jkcmm.2018.13.2.109