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The New Classification Criteria of Systemic Lupus Erythematosus

전신홍반루푸스의 새로운 분류기준

  • Lee, Sang-Heon (Division of Rheumatology, Department of Internal Medicine, Konkuk Universtiy School of Medicine)
  • 이상헌 (건국대학교 의학전문대학원 내과학교실)
  • Published : 2014.10.01

Abstract

Systemic lupus erythematosus (SLE) is a prototype for multi-system, autoimmune diseases of unknown etiology, characterized by the production of autoantibodies. SLE can involve any organ system of the body with constitutional symptoms, including musculoskeletal, skin, renal, neuropsychiatric, cardiovascular, respiratory and gastrointestinal systems. These wide spectra of disease manifestations have made disease classification difficult. American College of Rheumatology (ACR) proposed classification criteria for SLE for research purpose in 1982, which had been widely used for research purpose and not for diagnosis. In 1997, these criteria were updated with further recognition of antiphospholipid antibodies, but not validated. But ACR criteria didn't still meet the necessity for earlier diagnosis of SLE. In order to improve clinical relevance and incorporate new knowledge to the field of lupus immunology, the Systemic Lupus Erythematosus International Collaborating Clinics (SLICC), an international lupus expert group dedicated to clinical research on lupus, revised the ACR systemic lupus classification criteria in 2012. The new 2012 SLICC criteria were validated using a large set of patient scenarios rated by experts. The history and diagnostic utility of SLE criteria are covered in this review.

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References

  1. Hay EM. Systemic lupus erythematosus. Baillieres Clin Rheumatol 1995;9:437-470. https://doi.org/10.1016/S0950-3579(05)80252-3
  2. Tan EM, Cohen AS, Fries JF, et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982;25:1271-1277. https://doi.org/10.1002/art.1780251101
  3. Hochberg MC. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1997;40:1725.
  4. Petri M, Orbai AM, Alarcon GS, et al. Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus. Arthritis Rheum 2012;64:2677-2686. https://doi.org/10.1002/art.34473
  5. Fries JF, Siegel RC. Testing the 'preliminary criteria for classification of SLE'. Ann Rheum Dis 1973;32:171-177. https://doi.org/10.1136/ard.32.2.171
  6. Piette JC, Wechsler B, Francis C, Godeau P. Systemic lupus erythematosus and the antiphospholipid syndrome: reflections about the relevance of ARA criteria. J Rheumatol 1992;19:1835-1837.
  7. Feletar M, Ibanez D, Urowitz MB, Gladman DD. The impact of the 1997 update of the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus: what has been changed? Arthritis Rheum 2003;48:2067-2069. https://doi.org/10.1002/art.11167
  8. Eilertsen GO, Becker-Merok A, Nossent JC. The influence of the 1997 updated classification criteria for systemic lupus erythematosus: epidemiology, disease presentation, and patient management. J Rheumatol 2009;36:552-559. https://doi.org/10.3899/jrheum.080574
  9. Ippolito A, Wallace DJ, Gladman D, et al. Autoantibodies in systemic lupus erythematosus: comparison of historical and current assessment of seropositivity. Lupus 2011;20:250-255. https://doi.org/10.1177/0961203310385738
  10. Yu C, Gershwin ME, Chang C. Diagnostic criteria for systemic lupus erythematosus: a critical review. J Autoimmun 2014;48-49:10-13. https://doi.org/10.1016/j.jaut.2014.01.004
  11. Mehrani T, Petri M. IgM anti-$\beta$2 glycoprotein I is protective against lupus nephritis and renal damage in systemic lupus erythematosus. J Rheumatol 2011;38:450-453. https://doi.org/10.3899/jrheum.100650
  12. The American College of Rheumatology nomenclature and case definitions for neuropsychiatric lupus syndromes. Arthritis Rheum 1999;42:599-608. https://doi.org/10.1002/1529-0131(199904)42:4<599::AID-ANR2>3.0.CO;2-F
  13. Grönhagen CM, Gunnarsson I, Svenungsson E, Nyberg F. Cutaneous manifestations and serological findings in 260 patients with systemic lupus erythematosus. Lupus 2010;19:1187-1194. https://doi.org/10.1177/0961203310367656

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