The Korean Journal of Medicine

  • 제87권6호
  • /
  • Pages.750-755
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  • 2014
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  • 1738-9364(pISSN)
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  • 2289-0769(eISSN)
대한내과학회 (The Korean Association of Internal Medicine)
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성인 T세포 백혈병/림프종 환자에서 전이성 폐 석회화 1예

Metastatic Pulmonary Calcification in a Patient with Adult T-Cell Leukemia/Lymphoma

  • 김수정 (건국대학교 의학전문대학원 건국대학교병원 내과) ;
  • 강원찬 (건국대학교 의학전문대학원 건국대학교병원 내과) ;
  • 김선웅 (건국대학교 의학전문대학원 건국대학교병원 내과) ;
  • 이윤정 (건국대학교 의학전문대학원 건국대학교병원 내과) ;
  • 김욱연 (건국대학교 의학전문대학원 건국대학교병원 병리과) ;
  • 김현정 (건국대학교 의학전문대학원 건국대학교병원 진단검사의학과) ;
  • 이홍기 (건국대학교 의학전문대학원 건국대학교병원 내과)
  • Kim, SooJung (Department of Internal Medicine, Konkuk University Medical Center, Konkuk University School of Medicine) ;
  • Kang, Won Chan (Department of Internal Medicine, Konkuk University Medical Center, Konkuk University School of Medicine) ;
  • Kim, Sun Woong (Department of Internal Medicine, Konkuk University Medical Center, Konkuk University School of Medicine) ;
  • Lee, Yoon Jeong (Department of Internal Medicine, Konkuk University Medical Center, Konkuk University School of Medicine) ;
  • Kim, WookYoun (Department of Pathology, Konkuk University Medical Center, Konkuk University School of Medicine) ;
  • Kim, Hyun Jeong (Department of Laboratoy Medicine, Konkuk University Medical Center, Konkuk University School of Medicine) ;
  • Lee, Hong Ghi (Department of Internal Medicine, Konkuk University Medical Center, Konkuk University School of Medicine)
  • 투고 : 2014.04.02
  • 심사 : 2014.06.16
  • 발행 : 2014.12.01
⟨ 이전 논문 다음 논문 ⟩

초록

HTLV-1 관련 ATLL은 다양한 임상양상을 나타낼 수 있으며 그 중 고칼슘혈증이 동반된 급성형의 경우 그 예후는 좋지 않을 수 있다. 저자는 HTLV-1 관련 ATLL 환자에서 고칼슘혈증 및 전이성 석회화 폐결절이 진단된 환자에서 항암치료 변경투약 및 감염치료를 지속하였음에도 호전되지 않는 치명적인 증례를 경험하였기에 문헌고찰과 함께 이를 보고 하는 바이다.

Adult T-cell leukemia/lymphoma (ATLL) is a highly aggressive disease that is geographically clustered, mirroring areas endemic for human T-cell lymphotropic virus type 1 infection. Most patients with ATLL present with aggressive manifestations such as severe hypercalcemia, lymphadenopathy, hepatosplenomegaly, and bone marrow involvement with progressive thrombocytopenia. We herein report a case of a patient with ATLL exhibiting increased uptake in both lungs as shown on a bone scan using $^{99m}Tc$-methylene diphosphonate. This finding is thought to have been caused by metastatic calcification associated with ectopic parathyroid hormone production.

키워드

참고문헌

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