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감염성 장염에 합병된 신정맥 혈전증 1예

A Case of Infectious Enteritis complicated by Renal Venous Thrombosis

  • Choi, Jae Hyuc (Department of Internal Medicine, Dongkang Medical Center) ;
  • Cheon, Jong Woon (Department of Internal Medicine, Dongkang Medical Center) ;
  • Kang, Kee Hoon (Department of Internal Medicine, Dongkang Medical Center) ;
  • Kim, Seung Hyun (Department of Internal Medicine, Dongkang Medical Center) ;
  • Kim, Chung Hyoun (Department of Internal Medicine, Dongkang Medical Center) ;
  • Yun, Kyung Hyun (Department of Internal Medicine, Dongkang Medical Center) ;
  • Seo, Kum Soo (Department of Radiology, Dongkang Medical Center)
  • 투고 : 2013.11.06
  • 심사 : 2014.03.03
  • 발행 : 2014.12.01

초록

신정맥 혈전증은 신증후군에 이차적으로 발생하는 경우가 가장 흔하다. 감염과 관련한 신정맥 혈전증의 증례는 신우신염 및 신농양에 의한 것이 간혹 보고되었다. 71세의 여자가 복통, 구토 및 수양성 설사, 발열을 주소로 내원하였다. 복부 CT에서 전반적인 소장벽의 비후와 함께 좌측 신정맥 혈전증이 발견되었다. 금식 및 항생제 치료로 감염성 장염은 금방 호전되었고 함께 발견된 신정맥 혈전증에 대하여 항응고치료를 시작하였다. 3개월 뒤 시행한 복부 CT에서 신정맥 혈전은 많이 감소되었으나 국소적으로 약간 남아 있었다. 항응고요법을 4개월 더 시행한 후 촬영한 복부 CT에서 잔여 혈전은 큰 변화가 없었다. 그 후 와파린을 clopidogrel로 교체 하였고 8개월 뒤 시행한 추적 복부 CT에서 신정맥 혈전은 더 이상 보이지 않았다.

Renal venous thrombosis occurs, for the most part, as secondary to nephrotic syndrome. In relation to infection, cases complicated with acute pyelonephritis and renal abscess have been reported. A 71-year-old woman was admitted due to vomiting, abdominal pain, watery diarrhea, and fever. Abdominal computed tomography (CT) revealed diffuse thickening of the small intestinal wall and left renal venous thrombosis. The enteritis rapidly resolved with conservative treatment including fasting and antibiotic therapy; anticoagulation therapy was started. After 3 months, the renal vein thrombosis had much improved, but a tiny remnant thrombus was seen on follow-up abdominal CT. After 4 months of additional anticoagulation therapy, the remnant thrombus remained unchanged, at which point warfarin was switched to clopidogrel, an antiplatelet agent, and after 8 months the remnant thrombus was no longer visible on abdominal CT.

키워드

참고문헌

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