Clinical and Experimental Pediatrics

The Korean Pediatric Society (대한소아청소년과학회)
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BK virus-associated hemorrhagic cystitis after pediatric stem cell transplantation

  • Han, Seung Beom (Department of Pediatrics, The Catholic University of Korea College of Medicine) ;
  • Cho, Bin (Department of Pediatrics, The Catholic University of Korea College of Medicine) ;
  • Kang, Jin Han (Department of Pediatrics, The Catholic University of Korea College of Medicine)
  • Received : 2014.09.16
  • Accepted : 2014.10.08
  • Published : 2014.12.10
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Abstract

Hemorrhagic cystitis is a common stem cell transplantation-related complication. The incidence of early-onset hemorrhagic cystitis, which is related to the pretransplant conditioning regimen, has decreased with the concomitant use of mesna and hyperhydration. However, late-onset hemorrhagic cystitis, which is usually caused by the BK virus, continues to develop. Although the BK virus is the most common pathogenic microorganism of poststem cell transplantation late-onset hemorrhagic cystitis, pediatricians outside the hemato-oncology and nephrology specialties tend to be unfamiliar with hemorrhagic cystitis and the BK virus. Moreover, no standard guidelines for the early diagnosis and treatment of BK virus-associated hemorrhagic cystitis after stem cell transplantation have been established. Here, we briefly introduce poststem cell transplantation BK virus-associated hemorrhagic cystitis.

Keywords

References

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