Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Renal Amyloidosis in a Beagle

비글견에서 신장 아밀로이드증 증례

  • Jung, Joohyun (Ilsan animal medical center) ;
  • Jin, Jaebong (Ilsan animal medical center) ;
  • Lee, Hyunuk (Ilsan animal medical center) ;
  • Choi, Mincheol (Veterinary Radiology Department, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University)
  • Accepted : 2014.12.16
  • Published : 2014.12.31
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Abstract

An eight-year-old intact male Beagle had anorexia, vomiting, depression for two days. The dog had hypoalbuminenia and mild azotemia on hematologic and clinical chemistry examinations. Severe proteinuria was identified on urinalysis. On abdominal ultrasonographs, there were small amount of ascites and bilateral renomegaly with severe hyperechoic renal cortex and hyperechoic medullary rim sign. Renal biopsy and histopathology revealed renal amyloidosis. The quality of life in this dog was satisfactory with aggressive supportive care for three months. Euthanasia was performed due to deteriorated azotemia and nephrotic syndrome.

8년령의 수컷 비글견이 이틀 동안 식욕 부진, 구토, 기력 저하를 주증으로 내원하였다. 혈액학적 검사에서 경등도의 질소혈증과 심각한 저알부민혈증, 뇨 검사에서 심각한 단백뇨가 관찰되었다. 복부 초음파 검사에서 양쪽 신장의 크기가 증가하고 미만성 고에코의 피질이 두드러지게 관찰되었다. 신장 생검과 조직 검사 결과 신장 아밀로이드증으로 확진되었다. 3 개월 동안 환자는 적극적인 내과적 관리를 받았고, 보호자는 환자의 삶의 질에 만족하였다. 이후 심각한 질소혈증과 콩팥증후군이 발생하여 안락사가 실시되었다.

Keywords

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