DOI QR코드

DOI QR Code

Recurrent Herpes Simplex Virus Type-2 Meningitis in an Adolescent Girl

청소년기 여성에서 제2형 단순포진바이러스에 의한 재발성 뇌수막염

  • Hwang, YunSu (Department of Neurology, Wonkwang University School of Medicine Institute of Wonkwang Medical Science and Regional Cardiocerebrovascular Center) ;
  • Kim, YoungSeo (Department of Neurology, Wonkwang University School of Medicine Institute of Wonkwang Medical Science and Regional Cardiocerebrovascular Center) ;
  • Park, HyunYoung (Department of Neurology, Wonkwang University School of Medicine Institute of Wonkwang Medical Science and Regional Cardiocerebrovascular Center) ;
  • Park, HyungJong (Department of Neurology, Wonkwang University School of Medicine Institute of Wonkwang Medical Science and Regional Cardiocerebrovascular Center) ;
  • Cho, JiHyun (Department of Laboratory Medicine, Wonkwang University School of Medicine) ;
  • Park, DoSim (Department of Laboratory Medicine, Wonkwang University School of Medicine) ;
  • Cho, KwangHo (Department of Neurology, Wonkwang University School of Medicine Institute of Wonkwang Medical Science and Regional Cardiocerebrovascular Center)
  • 황윤수 (원광대학교 의과대학 신경과학교실, 원광의과학연구소 전북권역심뇌혈관센터) ;
  • 김영서 (원광대학교 의과대학 신경과학교실, 원광의과학연구소 전북권역심뇌혈관센터) ;
  • 박현영 (원광대학교 의과대학 신경과학교실, 원광의과학연구소 전북권역심뇌혈관센터) ;
  • 박형종 (원광대학교 의과대학 신경과학교실, 원광의과학연구소 전북권역심뇌혈관센터) ;
  • 조지현 (원광대학교 의과대학 진단검사의학과교실) ;
  • 박도심 (원광대학교 의과대학 진단검사의학과교실) ;
  • 조광호 (원광대학교 의과대학 신경과학교실, 원광의과학연구소 전북권역심뇌혈관센터)
  • Received : 2014.07.16
  • Accepted : 2014.11.11
  • Published : 2014.12.31

Abstract

Herpes simplex virus type 2 (HSV2) meningitis primarily develops during or following a primary genital HSV2 infection that was acquired from sexual contact or through the birth canal during delivery from mother. We describe a 15 year old virgin without history of previous herpes simplex infection who developed 2 episodes of HSV2 meningitis. Although recurrent meningitis due to HSV is primarily seen in young or sexually active adults. HSV2 meningitis should be in the differential diagnosis of recurrent meningitis in adolescent patients.

Keywords

References

  1. Shalabi M, Whitley RJ. Recurrent benign lymphocytic meningitis. Clin Infect Dis 2006;43:1194-1197. https://doi.org/10.1086/508281
  2. Davis LE, Guerre J, Gerstein WH. Recurrent herpes simplex virus type 2 meningitis in elderly persons. Arch Neurol 2010;67:759-760.
  3. Miller S, Mateen FJ, Aksamit AJ Jr. Herpes simplex virus 2 meningitis: a retrospective cohort study. J Neurovirol 2013;19:166-171. https://doi.org/10.1007/s13365-013-0158-x
  4. Steiner I, Benninger F. Update on herpes virus infections of nervous system. Curr Neurol Neurosci Rep 2013;13:414. https://doi.org/10.1007/s11910-013-0414-8
  5. Abu Khattab M, Al Soub H, Al Masalamani M, Al Khuwaiter J, El Deeb Y. Herpes simplex virus type 2 (Mollaret's) meningitis: a case report. Int J Infect Dis 2009 Mar 28 [Epub]. Doi:10.1016/jijd.2009.01.003.
  6. Kim SY, Yang EJ, Nam SU. A Case of Mollaret Meningitis. J Korean Pediatr Soc 1999;42:122-127.
  7. Kim MK, Sung TJ, Kim JK, Yang EJ, Hong YJ. A Case Mollaret Meningitis. Korean J Pediatr Infect Dis 2000;7:159-164.
  8. Benedetti J, Corey L, Ashley R. Recurrence rates in genital herpes after symptomatic first-episode infection. Ann Intern Med 1994;121:847-854. https://doi.org/10.7326/0003-4819-121-11-199412010-00004
  9. Jensenius M, Myrvang B, Storvold G, Bucher A, Hellum KB, Bruu AL. Herpes simplex virus type 2 DNA detected in cerebrospinal fluid of 9 patients with Mollaret's meningitis. Acta Neurol Scand 1998;98:209-212. https://doi.org/10.1111/j.1600-0404.1998.tb07296.x
  10. Forsgren M, Skoldenberg B, Aurelius E, Gille E. Neurologic morbidity after herpes simplex virus type 2 meningitis: a retrospective study of 40 patients. Scandinavian journal of infectious diseases 2002;34:278-283. https://doi.org/10.1080/00365540110080485