Journal of Acupuncture Research

Korean Acupuncture & Moxibustion Medicine Society (대한침구의학회)
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Safety of Acupuncture Therapy for Patients Undergoing Anticoagulants / antiplatelet-Hwalhyeolgeoeo Herbal Medication: Retrospective Casecontrol Study

항응고제 또는 항혈전제와 활혈거어 한약 병용환자에서 침치료 안전성에 대한 후향적 환자-대조군 연구

  • Lee, Min Jun (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Im, Se Hoon (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Lee, Seung Min (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Kim, Eun Seok (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Lee, Seung Hoon (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Kang, Jung Won (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Lee, Jae Dong (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Kyung Hee University)
  • 이민준 (경희대학교 한의과대학 침구의학교실) ;
  • 임세훈 (경희대학교 한의과대학 침구의학교실) ;
  • 이승민 (경희대학교 한의과대학 침구의학교실) ;
  • 김은석 (경희대학교 한의과대학 침구의학교실) ;
  • 이승훈 (경희대학교 한의과대학 침구의학교실) ;
  • 강중원 (경희대학교 한의과대학 침구의학교실) ;
  • 이재동 (경희대학교 한의과대학 침구의학교실)
  • Received : 2014.11.17
  • Accepted : 2014.11.29
  • Published : 2014.12.20
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Abstract

Objectives : The aim of this study is to evaluate the safety of acupuncture therapy when applied to patients who are undergoing anticoagulants / antiplatelet medication therapy combined with herbal medicine using a retrospective, case-control study. Methods : 428 charts of patients were reviewed in this study. Odds ratio between case of bleeding-related adverse event and control was calculated as main analysis. Exposures were anticoagulants / antiplatelet medication, Hwalhyeolgeoeo herbal medicine and combination of both drugs. Additionally, odds ratios were calculated according to the severity of bleeding-related adverse events. Results : The results were as following: 1. Analysis of all bleeding-related adverse events showed there was no increased risk of combined therapy compared with other exposures and control group. 2. Analysis of only clinically significant adverse events showed there was no increased risk of combined therapy compared with other exposure and control group. 3. Hwalhyeolgeoeo herbal medicine group showed a tendency of increased risk of bleeding-related adverse events in all analysis but was not statistically significant. Conclusions : The results suggest that Hwalhyeolgeoeo herbal medicine-anticoagulant / antiplatelet medication combined therapy may not increase risk of bleeding-related adverse events in acupuncture therapy. By executing various modules of analysis, it was possible to acquire useful data for possible future studies. Further research is needed to confirm such results.

Keywords

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