KSBB Journal

The Korean Society for Biotechnology and Bioengineering (한국생물공학회)
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Functional Characterization of Callus Extracts of Apple 'Hirosaki' for Cosmetic Materials

사과 '히로사키' 캘러스 추출물의 기능성 화장품 소재로서의 특성

  • 고승희 (바이오스펙트럼(주) 생명과학연구소) ;
  • 김영수 (바이오스펙트럼(주) 생명과학연구소) ;
  • 이진혁 (바이오스펙트럼(주) 생명과학연구소) ;
  • 김일현 (바이오스펙트럼(주) 생명과학연구소) ;
  • 김승범 (바이오스펙트럼(주) 생명과학연구소) ;
  • 노경백 (바이오스펙트럼(주) 생명과학연구소) ;
  • 신승우 (바이오스펙트럼(주) 생명과학연구소) ;
  • 정은선 (바이오스펙트럼(주) 생명과학연구소) ;
  • 박덕훈 (바이오스펙트럼(주) 생명과학연구소)
  • Received : 2013.07.04
  • Accepted : 2013.08.26
  • Published : 2013.08.30
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Abstract

In order to investigate functional characterization of callus extracts of apple 'Hirosaki' for cosmetic materials, biological activities of its extracts including wrinkle improvement, hair growth, and anti-inflammatory effect were investigated. The callus extract showed similar activity with TGF-${\beta}$ used as positive control at 50 ${\mu}g/mL$ in the test of collagen synthesis, and increased 40% of proliferation of hair follicle dermal papilla cells. Especially, in case of anti-inflammatory effect, callus extract inhibited about 50% of COX-2 expression which was known as response for intermediating inflammation, and about 70% of eotaxin-1 production which was increased by atopy dermatitis.

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References

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