DOI QR코드

DOI QR Code

Malignant Solitary Fibrous Tumor of Tandem Lesions in the Skull and Spine

  • Son, Seong (Department of Neurosurgery, Pathology, Gil Medical Center) ;
  • Lee, Sang-Gu (Department of Neurosurgery, Pathology, Gil Medical Center) ;
  • Jeong, Dong-Hae (Department of Neurosurgery, Gachon University, Gil Medical Center) ;
  • Yoo, Chan Jong (Department of Neurosurgery, Pathology, Gil Medical Center)
  • Received : 2012.12.28
  • Accepted : 2013.08.19
  • Published : 2013.09.28

Abstract

A solitary fibrous tumor (SFT) is a rare neoplasm originated from the pleura, but they can occur in a variety of extrathoracic regions. Although many cases of primary SFT have been reported, there are extremely rare repots to date of a malignant SFT in the spine or skull. A 54-year-woman visited our hospital due to low back pain and both leg radiating pain. Several imaging studies including magnetic resonance imaging and computed tomography revealed expansive enhanced lesions in the occipital bone, T8, S1-2, and ilium, with neural tissue compression. We performed surgical resection of the tumor in each site, and postoperative radiosurgery and chemotherapy were performed. However, after six months, tumors were recurred and metastasized in multiple regions including whole spine and lung. The authors report here the first case of patient with malignant SFT of tandem lesions in the various bony structures, including skull, thoracic spine, and sacral spine, with a rapid recurrence and metastasis. Although malignant SFT is extremely rare, it should be considered in the differential diagnosis and carful follow-up is needed.

Keywords

References

  1. Briselli M, Mark EJ, Dickersin GR : Solitary fibrous tumors of the pleura : eight new cases and review of 360 cases in the literature. Cancer 47 : 2678-2689, 1981 https://doi.org/10.1002/1097-0142(19810601)47:11<2678::AID-CNCR2820471126>3.0.CO;2-9
  2. Chan JK : Solitary fibrous tumour--everywhere, and a diagnosis in vogue. Histopathology 31 : 568-576, 1997 https://doi.org/10.1046/j.1365-2559.1997.2400897.x
  3. Chang ED, Lee EH, Won YS, Kim JM, Suh KS, Kim BK : Malignant solitary fibrous tumor of the pleura causing recurrent hypoglycemia; immunohistochemical stain of insulin-like growth factor i receptor in three cases. J Korean Med Sci 16 : 220-224, 2001 https://doi.org/10.3346/jkms.2001.16.2.220
  4. Cox DP, Daniels T, Jordan RC : Solitary fibrous tumor of the head and neck. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 110 : 79-84, 2010 https://doi.org/10.1016/j.tripleo.2010.01.023
  5. Demicco EG, Park MS, Araujo DM, Fox PS, Bassett RL, Pollock RE, et al. : Solitary fibrous tumor : a clinicopathological study of 110 cases and proposed risk assessment model. Mod Pathol 25 : 1298-1306, 2012 https://doi.org/10.1038/modpathol.2012.83
  6. Fargen KM, Opalach KJ, Wakefield D, Jacob RP, Yachnis AT, Lister JR : The central nervous system solitary fibrous tumor : a review of clinical, imaging and pathologic findings among all reported cases from 1996 to 2010. Clin Neurol Neurosurg 113 : 703-710, 2011 https://doi.org/10.1016/j.clineuro.2011.07.024
  7. Fukunaga M, Naganuma H, Nikaido T, Harada T, Ushigome S : Extrapleural solitary fibrous tumor : a report of seven cases. Mod Pathol 10 : 443-450, 1997
  8. Gengler C, Guillou L : Solitary fibrous tumour and haemangiopericytoma : evolution of a concept. Histopathology 48 : 63-74, 2006 https://doi.org/10.1111/j.1365-2559.2005.02290.x
  9. Gold JS, Antonescu CR, Hajdu C, Ferrone CR, Hussain M, Lewis JJ, et al. : Clinicopathologic correlates of solitary fibrous tumors. Cancer 94 : 1057-1068, 2002 https://doi.org/10.1002/cncr.10328
  10. Ha JK, Park BJ, Kim YH, Lim YJ : Orbital solitary fibrous tumor : a case report and diagnostic clues. J Korean Neurosurg Soc 46 : 77-80, 2009 https://doi.org/10.3340/jkns.2009.46.1.77
  11. Kawamura S, Nakamura T, Oya T, Ishizawa S, Sakai Y, Tanaka T, et al. : Advanced malignant solitary fibrous tumor in pelvis responding to radiation therapy. Pathol Int 57 : 213-218, 2007 https://doi.org/10.1111/j.1440-1827.2007.02083.x
  12. Klemperer P, Coleman BR : Primary neoplasms of the pleura. A report of five cases. Am J Ind Med 22 : 1-31, 1992 https://doi.org/10.1002/ajim.4700220102
  13. Mussak EN, Tu JJ, Voigt EP : Malignant solitary fibrous tumor of the hypopharynx with dysphagia. Otolaryngol Head Neck Surg 133 : 805-807, 2005 https://doi.org/10.1016/j.otohns.2004.11.009
  14. Nielsen GP, O'Connell JX, Dickersin GR, Rosenberg AE : Solitary fibrous tumor of soft tissue : a report of 15 cases, including 5 malignant examples with light microscopic, immunohistochemical, and ultrastructural data. Mod Pathol 10 : 1028-1037, 1997
  15. Okike N, Bernatz PE, Woolner LB : Localized mesothelioma of the pleura : benign and malignant variants. J Thorac Cardiovasc Surg 75 : 363-372, 1978
  16. Shnayder Y, Greenfield BJ, Oweity T, DeLacure MD : Malignant solitary fibrous tumor of the tongue. Am J Otolaryngol 24 : 246-249, 2003 https://doi.org/10.1016/S0196-0709(03)00007-3
  17. Sung SH, Chang JW, Kim J, Lee KS, Han J, Park SI : Solitary fibrous tumors of the pleura : surgical outcome and clinical course. Ann Thorac Surg 79 : 303-307, 2005 https://doi.org/10.1016/j.athoracsur.2004.07.013
  18. Vallat-Decouvelaere AV, Dry SM, Fletcher CD : Atypical and malignant solitary fibrous tumors in extrathoracic locations : evidence of their comparability to intra-thoracic tumors. Am J Surg Pathol 22 : 1501-1511, 1998 https://doi.org/10.1097/00000478-199812000-00007
  19. Westra WH, Grenko RT, Epstein J : Solitary fibrous tumor of the lower urogenital tract : a report of five cases involving the seminal vesicles, urinary bladder, and prostate. Hum Pathol 31 : 63-68, 2000 https://doi.org/10.1016/S0046-8177(00)80200-2
  20. Wignall OJ, Moskovic EC, Thway K, Thomas JM : Solitary fibrous tumors of the soft tissues : review of the imaging and clinical features with histopathologic correlation. AJR Am J Roentgenol 195 : W55-W62, 2010 https://doi.org/10.2214/AJR.09.3379

Cited by

  1. Mulitmodality management of rare solitary fibrous tumor can be associated with extended survival vol.5, pp.suppl16, 2014, https://doi.org/10.4103/2152-7806.148058
  2. Intramedullary Solitary Fibrous Tumor of Cervicothoracic Spinal Cord vol.56, pp.3, 2013, https://doi.org/10.3340/jkns.2014.56.3.265
  3. Rapid recurrence and bilateral lungs, multiple bone metastasis of malignant solitary fibrous tumor of the right occipital lobe: report of a case and review vol.10, pp.1, 2013, https://doi.org/10.1186/s13000-015-0318-9
  4. Solitary fibrous tumor of the ilium : A case report vol.96, pp.51, 2017, https://doi.org/10.1097/md.0000000000009355
  5. Solitary fibrous tumors of the spine: a pediatric case report with a comprehensive review of the literature vol.19, pp.3, 2013, https://doi.org/10.3171/2016.10.peds16279
  6. Solitary fibrous tumors of the spine: a pediatric case report with a comprehensive review of the literature vol.19, pp.3, 2013, https://doi.org/10.3171/2016.10.peds16279
  7. A malignant solitary fibrous tumour arising from the first lumbar vertebra and mimicking an osteosarcoma: a case report vol.15, pp.None, 2017, https://doi.org/10.1186/s12957-017-1161-0
  8. Solitary fibrous tumour of the spine: imaging features of a commonly misdiagnosed entity vol.28, pp.9, 2013, https://doi.org/10.1007/s00330-018-5349-7
  9. Surgical treatment of primary solitary fibrous tumors involving the pelvic ring vol.13, pp.11, 2013, https://doi.org/10.1371/journal.pone.0207581
  10. Solitary fibrous tumor of the seminal vesicle : A case report vol.98, pp.9, 2013, https://doi.org/10.1097/md.0000000000014660
  11. Case Report: A Malignant Liver and Thoracic Solitary Fibrous Tumor: A 10-Year Journey From the Brain to the Liver and the Spine vol.7, pp.None, 2020, https://doi.org/10.3389/fsurg.2020.570582
  12. Solitary fibrous tumor of bone developing lung metastases on long-term follow-up vol.49, pp.11, 2013, https://doi.org/10.1007/s00256-020-03493-x
  13. Solitary fibrous tumors: Clinical and imaging features from head to toe vol.146, pp.None, 2013, https://doi.org/10.1016/j.ejrad.2021.110053