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Primary Intraosseous Squamous Cell Carcinoma Arising from Odontogenic Cyst: A Case Report

치성 낭종으로부터 유래된 원발성 골내 편평상피세포 암종: 증례보고

  • Kim, Tae-Kwang (Department of Oral and Maxillofacial Surgery, School of Dentistry, Jeonbuk National University, Institute of Oral Bio-Science, Brain Korea 21 Project) ;
  • Lee, Sun-Jae (Department of Oral and Maxillofacial Surgery, School of Dentistry, Jeonbuk National University, Institute of Oral Bio-Science, Brain Korea 21 Project) ;
  • Leem, Dae-Ho (Department of Oral and Maxillofacial Surgery, School of Dentistry, Jeonbuk National University, Institute of Oral Bio-Science, Brain Korea 21 Project) ;
  • Baek, Jin-A (Department of Oral and Maxillofacial Surgery, School of Dentistry, Jeonbuk National University, Institute of Oral Bio-Science, Brain Korea 21 Project) ;
  • Shin, Hyo-Keun (Department of Oral and Maxillofacial Surgery, School of Dentistry, Jeonbuk National University, Institute of Oral Bio-Science, Brain Korea 21 Project) ;
  • Ko, Seung-O (Department of Oral and Maxillofacial Surgery, School of Dentistry, Jeonbuk National University, Institute of Oral Bio-Science, Brain Korea 21 Project)
  • 김태광 (전북대학교 치의학전문대학원 구강악안면외과학교실, 구강생체과학연구소, BK21사업) ;
  • 이선재 (전북대학교 치의학전문대학원 구강악안면외과학교실, 구강생체과학연구소, BK21사업) ;
  • 임대호 (전북대학교 치의학전문대학원 구강악안면외과학교실, 구강생체과학연구소, BK21사업) ;
  • 백진아 (전북대학교 치의학전문대학원 구강악안면외과학교실, 구강생체과학연구소, BK21사업) ;
  • 신효근 (전북대학교 치의학전문대학원 구강악안면외과학교실, 구강생체과학연구소, BK21사업) ;
  • 고승오 (전북대학교 치의학전문대학원 구강악안면외과학교실, 구강생체과학연구소, BK21사업)
  • Received : 2013.01.24
  • Accepted : 2013.03.26
  • Published : 2013.03.31

Abstract

Primary intraosseous squamous cell carcinoma (PIOSCC) is a rare form arising within the jaws. PIOSCC is not related to the oral mucosa, presumably developing from remnants of the odontogenic epithelium. Because odontogenic cyst epithelium often transforms malignantly into PIOSCC, it could be misdiagnosed as odontogenic cyst based on a relatively ill-defined radiolucent lesion. Therefore, definite diagnosis is established from histological examination of biopsy samples taken during cyst enucleation in many cases. The present study is reported with a case of patient complaining of discomfort on his mandible. He was diagnosed as a putative dentigerous cyst and underwent a cyst enucleation treatment. After definite diagnosis as PIOSCC was established based on histologic findings, partial mandible resection and mandible reconstruction were performed. Up to the present, 10 months follow up of the patient showed satisfactory healing without recurrence and abnormal findings; thereby, we are reporting this case with literature review.

Keywords

References

  1. To EH, Brown JS, Avery BS, Ward-Booth RP. Primary intraosseous carcinoma of the jaws. Three new cases and a review of the literature. Br J Oral Maxillofac Surg 1991;29:19-25. https://doi.org/10.1016/0266-4356(91)90168-5
  2. Bodner L, Manor E, Shear M, van der Waal I. Primary intraosseous squamous cell carcinoma arising in an odontogenic cyst: a clinicopathologic analysis of 116 reported cases. J Oral Pathol Med 2011;40:733-8. https://doi.org/10.1111/j.1600-0714.2011.01058.x
  3. Pindborg JJ, Kramer IRH, Torloni H, et al. Histologic typing of odontogenic tumors, jaw cysts and allied diseases. Geneva: World Health Organization; 1972. p. 35-6.
  4. Eversole LR, Siar CH, van der Waal I. Primary intraosseous squamous cell carcinomas. In: Barnes L, Evson JW, Reichart P, Sidransky D, editors. World Health Organization classification of tumors. Pathology and genetics head and neck tumors. World Health Organization International Agency for Research on Cancer. Lyon: IACR Press; 2005. p. 290-1.
  5. Punnya A, Kumar GS, Rekha K, Vandana R. Primary intraosseous odontogenic carcinoma with osteoid/dentinoid formation. J Oral Pathol Med 2004;33:121-4. https://doi.org/10.1111/j.1600-0714.2004.00029.x
  6. Kim HR, Ryu DM, Oh JH. Primary intraosseous carcinoma on mandible: a case report. J Korean Assoc Oral Maxillofac Surg 2007;33:263-7.
  7. Thomas G, Sreelatha KT, Balan A, Ambika K. Primary intraosseous carcinoma of the mandible--a case report and review of the literature. Eur J Surg Oncol 2000;26:82-6. https://doi.org/10.1053/ejso.1999.0746
  8. Mosqueda Taylor A, Meneses Garcia A, Ruiz Godoy Rivera LM, Suarez Roa Mde L, Luna Ortiz K. Malignant odontogenic tumors. A retrospective and collaborative study of seven cases. Med Oral 2003;8:110-21.
  9. Verneuil A, Sapp P, Huang C, Abemayor E. Malignant ameloblastoma: classification, diagnostic, and therapeutic challenges. Am J Otolaryngol 2002;23:44-8. https://doi.org/10.1053/ajot.2002.28769
  10. Bodner L, Manor E. Cystic lesions of the jaws--a review and analysis of 269 cases. Eur J Plastic Surg 2010;33:277-82. https://doi.org/10.1007/s00238-010-0415-7
  11. Van der Waal I, Rauhamaa R, Van der Kwast WA, Snow GB. Squamous cell carcinoma arising in the lining of odontogenic cysts. Report of 5 cases. Int J Oral Surg 1985;14:146-52. https://doi.org/10.1016/S0300-9785(85)80086-7
  12. Otten JE, Joos U, Schilli W. Carcinogenesis in the apex of the cyst-forming odontogenic epithelium. Dtsch Zahnarztl Z 1985;40:544-7.
  13. Waldron CA, Mustoe TA. Primary intraosseous carcinoma of the mandible with probable origin in an odontogenic cyst. Oral Surg Oral Med Oral Pathol 1989;67:716-24. https://doi.org/10.1016/0030-4220(89)90014-5
  14. Muller S, Waldron CA. Primary intraosseous squamous carcinoma. Report of two cases. Int J Oral Maxillofac Surg 1991;20:362-5. https://doi.org/10.1016/S0901-5027(05)80267-X
  15. Kim CH, Kim MS. Primary intraosseous carcinoma (PIOC) on mandible: case report. J Korean Assoc Maxillofac Plast Reconstr Surg 1997;19:200-8.
  16. Makowski GJ, McGuff S, Van Sickels JE. Squamous cell carcinoma in a maxillary odontogenic keratocyst. J Oral Maxillofac Surg 2001;59:76-80. https://doi.org/10.1053/joms.2001.19297
  17. Zwetyenga N, Pinsolle J, Rivel J, Majoufre-Lefebvre C, Faucher A, Pinsolle V. Primary intraosseous carcinoma of the jaws. Arch Otolaryngol Head Neck Surg 2001;127:794-7.
  18. Suei Y, Tanimoto K, Taguchi A, Wada T. Primary intraosseous carcinoma: review of the literature and diagnostic criteria. J Oral Maxillofac Surg 1994;52:580-3. https://doi.org/10.1016/0278-2391(94)90094-9
  19. Pogrel MA, Podlesh S, Anthony JP, Alexander J. A comparison of vascularized and nonvascularized bone grafts for reconstruction of mandibular continuity defects. J Oral Maxillofac Surg 1997;55:1200-6. https://doi.org/10.1016/S0278-2391(97)90165-8
  20. Tidstrom KD, Keller EE. Reconstruction of mandibular discontinuity with autogenous iliac bone graft: report of 34 consecutive patients. J Oral Maxillofac Surg 1990;48:336-46. https://doi.org/10.1016/0278-2391(90)90427-4
  21. Chen YB, Chen HC, Hahn LH. Major mandibular reconstruction with vascularized bone grafts: indications and selection of donor tissue. Microsurgery 1994;15:227-37. https://doi.org/10.1002/micr.1920150403
  22. Choi JW, Lee CO, Hwang HD, et al. Evaluation of Bone resorption rate after nonvascularized iliac bone graft for mandibular discontinuity defect. J Korean Assoc Maxillofac Plast Reconstr Surg 2012;34:398-403.
  23. Eversole LR, Sabes WR, Rovin S. Aggressive growth and neoplastic potential of odontogenic cysts: with special reference to central epidermoid and mucoepidermoid carcinomas. Cancer 1975;35:270-82. https://doi.org/10.1002/1097-0142(197501)35:1<270::AID-CNCR2820350134>3.0.CO;2-Y
  24. Thomas G, Pandey M, Mathew A, et al. Primary intraosseous carcinoma of the jaw: pooled analysis of world literature and report of two new cases. Int J Oral Maxillofac Surg 2001;30:349-55. https://doi.org/10.1054/ijom.2001.0069
  25. Tomomatsu N, Uzawa N, Michi Y, Kurohara K, Okada N, Amagasa T. Clinical study of keratocystic odontogenic tumors. J Korean Assoc Oral Maxillofac Surg 2012;38:55-63. https://doi.org/10.5125/jkaoms.2012.38.1.55
  26. Myoung H, Hong SP, Hong SD, et al. Odontogenic keratocyst: Review of 256 cases for recurrence and clinicopathologic parameters. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2001;91:328-33. https://doi.org/10.1067/moe.2001.113109
  27. Choi ST, Kim TK, Leem DH, Baek JA, Shin HK, Ko SO. Carnoy's solution application for patient preliminarily diagnosed with keratocystic odotogenic tumor: case report. J Korean Assoc Maxillofac Plast Reconstr Surg 2012;34:498-504.