DOI QR코드

DOI QR Code

Factors Associated with the Lumbar Spine and Femoral Neck Bone Mineral Density in Korean Elderly Women

한국 여성 노인의 대퇴경부 및 요추 골밀도 관련 요인

  • Kim, Young-Ran (Department of Preventive Medicine and Public Health, Chungnam National University School of Medicine) ;
  • Lee, Tae-Yong (Department of Preventive Medicine and Public Health, Chungnam National University School of Medicine)
  • 김영란 (충남대학교 의학전문대학원 예방의학교실) ;
  • 이태용 (충남대학교 의학전문대학원 예방의학교실)
  • Received : 2013.07.05
  • Accepted : 2013.10.10
  • Published : 2013.10.31

Abstract

This study was conducted among Korean women over aged 60 who participated in Korea National Health and Nutrition Examination Survey (KNHANES) (the 2nd and 3rd year at the 4th survey, and the 1st year at the 5th survey). The purpose of the study was to figure out a relation between femoral neck and lumbar spine bone mineral density and anthropometry, life style, diet, fracture history, family history of osteoporosis, medical history, menstrual history and reproductive factor. To express the strength of the associations, percent differences were calculated from multiple linear regression models using the formula ${\beta}{\times}$(unit/mean BMD). Unit for continuous variables were chosen to approximate 1 standard deviation(SD). In women aged 60 or older, lean mass(B: 0.257) and fat mass(B: 0.237) greatly influenced bone density in the femoral neck and lumbar spine. Therefore it will be an effective way to prevent osteoporosis for elderly women by increasing lean mass and maintaining proper weight.

본 연구는 국민건강영양조사 제 4기 2 3차년도, 제 5기 1차 년도에 참여한 60세 이상 여성노인을 대상으로 하였다. 연구의 목적으로는 신체계측, 생활습관, 식이섭취, 골절 과거력, 골다공증 가족력, 병력, 월경력 및 산과적 요인 등의 제 요인들과 대퇴경부 골밀도와 요추골밀도의 관련성을 알아보고자 시도하였다. 각 변수의 단위별 BMD의 변화를 표현하기 위해 비율차이 계산식 ${\beta}{\times}$(단위/BMD의 평균)를 이용한 다중선형회귀분석을 실시하였다. 모든 연속 변수의 단위는 1 표준편차를 사용하였다. 연구결과, 대퇴경부 및 요추 골밀도에 조사된 각 독립변수 중 여성노인의 골밀도에 가장 큰 영향을 미치는 것은 대퇴경부 부위에서는 제지방량(B: 0.257), 요추 부위에서는 체지방(B: 0.237)으로 확인되었다. 따라서 여성노인에서는 제지방량을 늘리고, 적절한 체중을 유지하는 것이 골다공증을 예방하는 효과적인 방안이 될 것이다.

Keywords

References

  1. Statistics Korea. Http://sgis. kostat. go. kr/publicsmodel/, 2012.
  2. Ministry for health welfare and family affairs, Korean center for disease control & preventive. Article 5 of the KNHANES year 1st(2010) report the results, 2010.
  3. National Health Insurance. Http://www. nhic.or.kr/potal/site/main/menuitem.31f148, 2010.
  4. Korean Journal of Bone Metabolism. Physicians Guide for Diagnosis & Treatment of Osteoporosis. 2008.
  5. Lee HY, Choi SM. Metabolic syndrome and bone mineral density among elderly korean women. J Korea Biol Nurs Sci, 13(2), pp. 134-141, 2011.
  6. Chung JW, Lee YH, Lee EK, Jin YS. Relationships of bone mineral density, body composition and fitness in older persons. Journal of korean physical education association for girls and women. 22(1), pp. 123-136, 2008.
  7. Oh HJ, Moon WN, Han IK, Effects of obestiy on bone mineral density in aged Korean women, J Korean Acad Fam Med, 12(21), pp. 1560-1567, 2000.
  8. Cameron JR, Sorenson JA. Measurement of bone mineral in vivo; an improved method. Science, 142, pp. 230-232, 1963. DOI: http://dx.doi.org/10.1126/science.142.3589.230
  9. Cauley JA, Blackwell Terri, Zmuda JM, Fullman RL, Ensrud KE, Stone KL et al. Correlates of trabecular and cortical volumetric bone mineral density at the femoral neck and lumber spine: the osteoporotic fractures in men study(MrOS). JBMR, 25(9), pp. 1958-1971, 2010. https://doi.org/10.1002/jbmr.86
  10. Hill DD, Cauley JA, Bunker CH, Carol EB, Patrick AL, Backles Gloria LA. Correlates of bone mineral desity among postmenopausal women of Africa Caribbean Ancestry: Tobago Women' Health Study. Bone, 43(1), pp. 156-161, 2008. DOI: http://dx.doi.org/10.1016/j.bone.2008.03.005
  11. Jung JS. Difference by sex in the association between body composition and bone mineral density in middle aged and elderly Korean. Seoul National University, Seoul Korea, 2010.
  12. Lim Su. Body composition changes with age has different impact on the bone mineral density. Seoul National University, Seoul Korea, 2004.
  13. Chung JE, Hwang SJ, Kim MJ, Song JY, Cho HH, Kwon DJ, Lew YO, Lim YT, Kim EJ, Kim JH, Kim JH, Kim MR. Relationship between body composition and bone mineral density in Pre-and Post-menopausal women. Journal of Korean Society of Menopause, 16(1), pp. 29-38, 2010.
  14. Blain H, Carriere I, Favier F, Jeandel C, Papoz L, EPIDOS study Group. Body weight change since menopause and Percent body fat mass are predictors of subsequent bone mineral density change of the proximal femur in women aged 75 years and older: results of a 5 year prospective study. Calcif Tissue Int, 75(1), pp. 32-39, 2004. DOI: http://dx.doi.org/10.1007/s00223-003-0192-4
  15. Pluijm SM, Visser M, Smit JH, Popp-Snijders C, Roos JC, Lips P, Determinants of bone mineral density in older men and women: body composition as mediator, J Bone Miner Res, 16(11), pp. 2142-2151, 2001. DOI: http://dx.doi.org/10.1359/jbmr.2001.16.11.2142
  16. Shin CS, Choi HJ, Kim MJ, Kim JT, Yu SH, Koo BK. Prevalence and risk factors of osteoporosis in Korea: A community-based cohort study with lumbar spine and hip bone mineral density. Bone, 47(2), pp. 378-387, 2010. DOI: http://dx.doi.org/10.1016/j.bone.2010.03.017
  17. Han SH. The effects of several factors on bone mineral density in Korean postmenopausal women over 55 years old. In ha University, 2000.
  18. Bjarnason K, Hassager C, Ravn P, Christiansen C. Early postmenopausal diminution of forearm and spinal bone mineral density : A cross-sectional study. Osteoporos Int. 5(1), pp. 35-38, 1995. DOI: http://dx.doi.org/10.1007/BF01623656
  19. Writing group for the women's health initiative investigators. Risk and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial. JAMA, 288, pp. 321-333, 2002. DOI: http://dx.doi.org/10.1001/jama.288.3.321