Asian Pacific Journal of Cancer Prevention

Asian Pacific Journal of Cancer Prevention (아시아태평양암예방학회)
권호 표지
DOI QR코드

DOI QR Code

Breastfeeding and the Risk of Childhood Hodgkin Lymphoma: A Systematic Review and Meta-analysis

  • Wang, Ke-Lai (Department of Pediatric Surgery, Qilu Hospital of Shandong University) ;
  • Liu, Chun-Lan (Department of Pediatric Surgery, Qilu Hospital of Shandong University) ;
  • Zhuang, Yan (Department of Pediatric Surgery, Qilu Hospital of Shandong University) ;
  • Qu, Hong-Yi (Department of Pediatric Surgery, Qilu Hospital of Shandong University)
  • Published : 2013.08.30
Download PDF
⟨ Previous Next ⟩

Abstract

Purpose: Numerous observational epidemiological studies have evaluated associations between breastfeeding and the risk of childhood Hodgkin lymphoma; however, the existing results are inconsistent. We therefore conducted a systematic review and meta-analysis. Methods: Medical literature was searched in the Pubmed and Embase databases to identify all English-language relevant studies up to April 10, 2013. Reference lists were thereafter hand-searched for additional articles. Studies that reported relative risk ratios (RRs) or odds ratios (ORs) with 95% confidence intervals (CIs) were included. This meta-analysis was conducted in accordance with the guidelines for the meta-analysis of observational studies in epidemiology. Results: We finally included 10 case-control studies in our meta-analysis, involving 1,618 childhood Hodgkin lymphoma cases and 8,181 controls. Overall, we did found a borderline significant association between breastfeeding and reduced risk of childhood Hodgkin lymphoma comparing ever breastfed children to never breastfed children (pooled OR =0.79; 95%CI, 0.58-1.08; P=0.13), with limited evidence for between-study heterogeneity (P =0.12, $I^2$ = 35.70%). Conclusion: There is limited evidence for an inverse association between breastfeeding and risk of childhood Hodgkin lymphoma.

Keywords

References

  1. Altinkaynak S, Selimoglu MA, Turgut A, Kilicaslan B, Ertekin V (2006). Breast-feeding duration and childhood acute leukemia and lymphomas in a sample of Turkish children. J Pediatr Gastroenterol Nutr, 42, 568-72. https://doi.org/10.1097/01.mpg.0000215309.93911.84
  2. Bener A, Denic S, Galadari S (2001). Longer breast-feeding and protection against childhood leukaemia and lymphomas. Eur J Cancer, 37, 234-8.
  3. Bener A, Hoffmann GF, Afify Z, Rasul K, Tewfik I (2008). Does prolonged breastfeeding reduce the risk for childhood leukemia and lymphomas? Minerva Pediatr, 60, 155-61
  4. Das UN (2007). Breastfeeding prevents type 2 diabetes mellitus: but, how and why? Am J Clin Nutr, 85, 1436-7.
  5. Davanzo R, Zauli G, Monasta L, et al (2013). Human colostrum and breast milk contain high levels of TNF-related apoptosis-inducing ligand (TRAIL). J Hum Lact, 29, 23-5. https://doi.org/10.1177/0890334412441071
  6. Davis MK, Savitz DA, Graubard BI (1988). Infant feeding and childhood cancer. Lancet, 2, 365-8
  7. Dinand V, Arya LS (2006). Epidemiology of childhood Hodgkins disease: is it different in developing countries? Indian Pediatr, 43, 141-7.
  8. Flavell KJ, Murray PG (2000). Hodgkin's disease and the Epstein-Barr virus. Mol Pathol, 53, 262-9. https://doi.org/10.1136/mp.53.5.262
  9. Grufferman S, Davis MK, Ambinder RF, et al (1998). A protective effect of breast-feeding on risk of Hodgkin’s disease in children. Paediatr Perinatal Epidemiol, 12, A13.
  10. Hardell L, Dreifaldt AC (2001). Breast-feeding duration and the risk of malignant diseases in childhood in Sweden. Eur J Clin Nutr, 55, 179-85 https://doi.org/10.1038/sj.ejcn.1601142
  11. Hjalgrim H (2012). On the aetiology of Hodgkin lymphoma. Dan Med J, 59, B4485.
  12. Hosea Blewett HJ, Cicalo MC, et al (2008). The immunological components of human milk. Adv Food Nutr Res, 54, 45-80. https://doi.org/10.1016/S1043-4526(07)00002-2
  13. Ip S, Chung M, Raman G, et al (2007). Breastfeeding and maternal and infant health outcomes in developed countries. Evid Rep Technol Assess (Full Rep), 153, 1-186.
  14. Ladomenou F, Moschandreas J, Kafatos A, Tselentis Y, Galanakis E (2010). Protective effect of exclusive breastfeeding against infections during infancy: a prospective study. Arch Dis Child Dec, 95, 1004-8. https://doi.org/10.1136/adc.2009.169912
  15. Landgren O, Caporaso NE (2007). New aspects in descriptive, etiologic, and molecular epidemiology of Hodgkin's lymphoma. Hematol Oncol Clin North Am, 21, 825-40. https://doi.org/10.1016/j.hoc.2007.07.001
  16. Martin RM, Gunnell D, Owen CG, Smith GD (2005). Breast-feeding and childhood cancer: A systematic review with metaanalysis. Int J Cancer, 117, 1020-31. https://doi.org/10.1002/ijc.21274
  17. Monterrosa EC, Frongillo EA, Vasquez-Garibay EM, et al (2008). Predominant breast-feeding from birth to six months is associated with fewer gastrointestinal infections and increased risk for iron deficiency among infants. J Nutr, 138, 1499-504.
  18. Mossberg AK, Hun Mok K, Morozova-Roche LA, Svanborg C (2010). Structure and function of human alpha-lactalbumin made lethal to tumor cells (HAMLET)-type complexes. FEBS J, 277, 4614-25. https://doi.org/10.1111/j.1742-4658.2010.07890.x
  19. Nakatsuka S, Aozasa K (2006). Epidemiology and pathologic features of Hodgkin lymphoma. Int J Hematol, 83, 391-7. https://doi.org/10.1532/IJH97.05184
  20. Oddy WH, Sly PD, de Klerk NH, et al (2003). Breast feeding and respiratory morbidity in infancy: a birth cohort study. Arch Dis Child, 88, 224-8. https://doi.org/10.1136/adc.88.3.224
  21. Paltiel O, Laniado DE, Yanetz R, et al (2006). The risk of cancer following hospitalization for infection in infancy: a population-based cohort study. Cancer Epidemiol Biomarkers Prev, 15, 1964-8. https://doi.org/10.1158/1055-9965.EPI-06-0313
  22. Paramasivam K, Michie C, Opara E, et al (2006). Human breast milk immunology: a review. Int J Fertil Womens Med, 51, 208-17.
  23. Petridou E, Andrie E, Dessypris N, Dikalioti SK, Trichopoulos D (2006). Incidence and characteristics of childhood Hodgkin's lymphoma in Greece: a nationwide study (Greece). Cancer Causes Control, 17, 209-15. https://doi.org/10.1007/s10552-005-0409-0
  24. Rosenbauer J, Herzig P, Giani G (2008). Early infant feeding and risk of type 1 diabetes mellitus-a nationwide population-based case-control study in pre-school children. Diabetes Metab Res Rev, 24, 211-22. https://doi.org/10.1002/dmrr.791
  25. Rudant J, Orsi L, Monnereau A, et al (2011). Childhood Hodgkin's lymphoma, non-Hodgkin's lymphoma and factors related to the immune system: the Escale Study (SFCE). Int J Cancer, 129, 2236-47. https://doi.org/10.1002/ijc.25862
  26. Section on Breastfeeding (2012). Breastfeeding and the use of human milk. Pediatrics, 129, e827-841. https://doi.org/10.1542/peds.2011-3552
  27. Shu XO, Clemens J, Zheng W, Ying DM, Ji BT, Jin F (1995). Infant breastfeeding and the risk of childhood lymphoma and leukaemia. Int J Epidemiol, 24, 27-32 https://doi.org/10.1093/ije/24.1.27
  28. Smulevich VB, Solionova LG, Belyakova SV (1999). Parental occupation and other factors and cancer risk in children: I. Study methodology and non-occupational factors. Int J Cancer, 83, 712-7. https://doi.org/10.1002/(SICI)1097-0215(19991210)83:6<712::AID-IJC2>3.0.CO;2-D
  29. Stang A (2010). Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. Eur J Epidemiol, 25, 603-5. https://doi.org/10.1007/s10654-010-9491-z
  30. Stroup DF, Berlin JA, Morton SC, et al (2000). Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis of Observational Studies in Epidemiology (MOOSE) group. JAMA, 283, 2008-12. https://doi.org/10.1001/jama.283.15.2008
  31. Swerdlow AJ (2003). Epidemiology of Hodgkin's disease and non-Hodgkin's lymphoma. Eur J Nucl Med Mol Imaging, 30, S3-12. https://doi.org/10.1007/s00259-003-1154-9
  32. UK Childhood Cancer Study Investigators (2001). Breastfeeding and childhood cancer. Br J Cancer, 85, 1685-94. https://doi.org/10.1054/bjoc.2001.2110
  33. World Health Organization (2010).http://www.who.int/mediacentre/factsheets/fs342/en/index.html

Cited by

  1. Breastfeeding and Ovarian Cancer Risk: a Systematic Review and Meta-analysis of 40 Epidemiological Studies vol.15, pp.12, 2014, https://doi.org/10.7314/APJCP.2014.15.12.4829
  2. Characteristics of Hodgkin Lymphoma in a Defined Group of Iranian Pediatric Patients vol.15, pp.13, 2014, https://doi.org/10.7314/APJCP.2014.15.13.5167