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Field evaluation of Enterotoxigenic Escherichia coli-specific bacteriophage (ΦCJ19) as a feed additive

Enterotoxigenic Escherichia coli 특이 박테리오파지 (ΦCJ19)의 사료 첨가제로서의 사양 평가

  • Yoo, Anna (College of Veterinary Medicine, Seoul National University) ;
  • Cha, Seung Bin (College of Veterinary Medicine, Seoul National University) ;
  • Shin, Min Kyoung (College of Veterinary Medicine, Seoul National University) ;
  • Park, Hong Tae (College of Veterinary Medicine, Seoul National University) ;
  • Seo, Hyo Sil (Research Institute of Biotechnology, CJ Cheil Jedang Co.) ;
  • Kim, Jae Won (Research Institute of Biotechnology, CJ Cheil Jedang Co.) ;
  • Yoo, Han Sang (College of Veterinary Medicine, Seoul National University)
  • 유안나 (서울대학교 수의과대학) ;
  • 차승빈 (서울대학교 수의과대학) ;
  • 신민경 (서울대학교 수의과대학) ;
  • 박홍태 (서울대학교 수의과대학) ;
  • 서효실 (CJ 제일제당 바이오기술연구소) ;
  • 김재원 (CJ 제일제당 바이오기술연구소) ;
  • 유한상 (서울대학교 수의과대학)
  • Received : 2013.01.08
  • Accepted : 2013.03.08
  • Published : 2013.06.30

Abstract

Field efficacy of enterotoxigenic Escherichia coli-specific phage (${\Phi}CJ19$) as a feed additive was evaluated in weaning piglets. Fifty-four piglets at 3-4 weeks old were allocated in three different groups and two of them were fed with bacteriophage at different concentrations ($10^6PFU/kg$ feed and $10^8PFU/kg$ feed, respectively) for 30 days. Body weight and feed intake were measured at 10 days interval and body condition and fecal score were inspected every day. Based on the measurement, feed conversion rate (FCR) and average daily gain (ADG) of each group during 30 days were analyzed. The analysis suggests that the bacteriophage may help the improvement of FCR and ADG at $10^8PFU/kg$ of bacteriophage feeding group in 30 days. A result from analysis of fecal score indicates that the bacteriophage also may help to relieve the intermittent diarrhea in post-weaning stage. Those results suggest that bacteriophage might help the growth of piglets in post-weaning stage.

Keywords

References

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