DOI QR코드

DOI QR Code

Development of Information Biology (II)

  • Tateno, Yoshio (School of New Biology, Daegu Gyeongbuk Institute of Science and Technology)
  • Received : 2013.04.22
  • Accepted : 2013.05.06
  • Published : 2013.06.28

Abstract

A history of discoveries of a gene and DNA was viewed with respect to people, time and places. It started with G. Mendel and J. Meisher, who discovered a gene in a plant species in 1866 and DNA in animals in 1869, respectively. With recognition that DNA was a chemical substance, A. Kossel identified the four chemical components of DNA without knowing their biological function around the turn of the 19th century. On the other hand F. Griffith found a peculiar activity in a bacterial species in 1928, but victimized by the war before understanding what it was. Those discoveries were made in Europe, but they were still fragmentary. Then, in USA, O. T. Avery, A. Hershey, M. Nirenberg and other scientists organized the European discoveries and elucidated their coordinated biological functions in 1950's and 1960'.

Keywords

References

  1. Griffith, F. (1928). The Significance of Pneumococcal Types. The Journal of Hygiene 27, 113-159. https://doi.org/10.1017/S0022172400031879
  2. Avery, O. T., Macleod, C. M., and McCarty, M. (1944). Studies on the Chemical Nature of the Substance Inducing Transformation of Pneumococcal Types: Induction of Transformation by a Desoxyribonucleic Acid Fraction Isolated from Pneumococcus Type Iii. The Journal of Experimental Medicine 79, 137-158. https://doi.org/10.1084/jem.79.2.137
  3. Hershey, A. D., and Chase, M. (1952). Independent functions of viral protein and nucleic acid in growth of bacteriophage. The Journal of General Physiology 36, 39-56. https://doi.org/10.1085/jgp.36.1.39
  4. Leder, P., and Nirenberg, M. W. (1964). Rna Codewords and Protein Synthesis, 3. On the Nucleotide Sequence of a Cysteine and a Leucine Rna Codeword. Proceedings of the National Academy of Sciences of the United States of America 52, 1521-1529. https://doi.org/10.1073/pnas.52.6.1521