DOI QR코드

DOI QR Code

Supernumerary Teeth in Monozygotic Twins

일란성 쌍생아들에서 관찰된 과잉치

  • Kim, Sohyun (Department of Pediatric Dentistry, School of Dentistry, Kyungpook National University) ;
  • Kim, Young-Jin (Department of Pediatric Dentistry, School of Dentistry, Kyungpook National University) ;
  • Kim, Hyun-Jung (Department of Pediatric Dentistry, School of Dentistry, Kyungpook National University) ;
  • Nam, Soon-Hyeun (Department of Pediatric Dentistry, School of Dentistry, Kyungpook National University)
  • 김소현 (경북대학교 치의학전문대학원 소아치과학교실) ;
  • 김영진 (경북대학교 치의학전문대학원 소아치과학교실) ;
  • 김현정 (경북대학교 치의학전문대학원 소아치과학교실) ;
  • 남순현 (경북대학교 치의학전문대학원 소아치과학교실)
  • Received : 2013.01.18
  • Accepted : 2013.07.24
  • Published : 2013.08.30

Abstract

Although the first case of supernumerary teeth had been documented almost 20 centuries ago, the etiology of supernumerary teeth still remains unclear. The prevalence of supernumerary teeth in the general Asian population is between 2.7% and 3.4%. The pathogenesis of supernumerary teeth has been attributed to phylogenetic reversion(atavism), splitting of the tooth bud(dichotomy theory), locally induced hyperactivity of the dental lamina and a combination of genetic and environmental factors(unified etiologic explanation). This report describes 3 cases of monozygotic twins with mesiodens who visited the pediatric dental clinic of Kyungpook national university hospital, and this is significant to support genetic factors involoved in the development of supernumerary teeth.

과잉치의 발생 원인 및 빈도, 치료 등 과잉치에 대한 많은 선학의 연구가 있었으나, 현재에 있어서도 과잉치의 발생 원인은 여전히 명확하지 않은 상태이다. 전체 인구에서 0.15%~1.0%의 발병률을 보이는 과잉치의 병인론으로는 계통발생학적 돌연변이(atavism), 치배분열론(dichotomy theory), 치아판의 국소적인 증식 그리고 유전 및 환경적 요인들의 조합(unified etiologic explanation) 등이 있다. 동일한 수정란으로부터 생긴 쌍생아인 일란성 쌍생아는 유전학적으로 동일한 개체이다. 이들에게서 나타난 과잉치에 대한 보고는 과잉치의 병인론에 있어 유전적인 요인이 강하게 작용함을 뒷받침할 수 있다는 면에서 의미를 가진다. 본 연구에서는 경북대학교 치과병원 소아치과 외래를 내원한 3쌍의 일란성 쌍생아에서 나타난 과잉치를 관찰하였으며, 이는 유전적인 원인에 의한 과잉치의 발생을 뒷받침함에 의미가 있어 보고하는 바이다.

Keywords

References

  1. Schulze C : Developmental abnormalities of the teeth and jaws. Thoma's Oral Pathology, 6th ed. Vol. 1. CV Mosby Co., 112-122, 1971.
  2. Weinberger BW : An introduction to the History of Dentistry. Mosby, 514, 1948.
  3. Sedano HO, Gorlin RJ. : Familial occurrence of mesiodens. Oral Surg Oral Med Oral Pathol, 27:360-361, 1969. https://doi.org/10.1016/0030-4220(69)90366-1
  4. Shafer WG, Hine MK, Levy BM. : Developmental disturbances of oral and paraoral structures. A Textbook of Oral Pathology, 4th ed. Philadelphia, Saunders, 47-49, 1983.
  5. Hattab FN, Yassin OM, Rawashdeh MA. : Sumpernumerary teeth : report of three cases and review of the literature. ASDC J Dent Child, 61: 382-393, 1994.
  6. Osburne JM : How to plan a Dental Fair. J Colo Dent Assoc, 44:25-34, 1966.
  7. Thoma GE : Case report : mesiodens. Dent Surv, 42:48-49, 1966.
  8. Gysel C. : Mesiodentes familiales. Rev Belge Med Dent, 18:929-960, 1963.
  9. Brook AH : A unifying aetiological explanation for anomalies of human tooth number and size. Arch Oral Biol, 29:373-378, 1984. https://doi.org/10.1016/0003-9969(84)90163-8
  10. Choi WK, Chang RC, Chuang ST : Bilateral mesiodentes of identical twins - a case report. Zhonghua Ya Yi Xue Hui Za Zhi, 9:116-21, 1990.
  11. Seddon RP, Johnstone SC, Smith PB. : Mesiodentes in twins : a case report and a review of the literature. Int J Paediatr Dent, 7:177-184, 1997.
  12. Langowska-Adamsczyk H, Karmanska B. : Similar locations of impacted and supernumerary teeth in monozygotic twins : a report of 2 cases. Am J Orthod Dentofacial Orthop, 119:67-70, 2001. https://doi.org/10.1067/mod.2001.111225
  13. Hunstadbraten K. : Anomalien bei Zwilingen. Quintessenz, 16:71-72, 1965.
  14. Carton A, Rees RT. : Mirror image dental anomalies in identical twins. Br Dent J, 162:193-194, 1987. https://doi.org/10.1038/sj.bdj.4806071
  15. Rajab LD, Hamdan MA. : Supernumerary teeth : review of the literature and a survey of 152 cases. Int j Paediatr Dent. 12:244-254, 2002. https://doi.org/10.1046/j.1365-263X.2002.00366.x
  16. Lundstom A. : Tooth morphology as a basis for distinguishing monozygotic and dizygotic twins. Am J Hum Genet, 15:34-43, 1963.
  17. Choi BJ, Lee YS, Kim SO, Lee JH : Study of invertly impacted supernumerary teeth in the midpalatal region using computerized tomography. J Korean Acad Pediatr Dent, 30:363-372, 2003.
  18. Kim JT : A study on the supernumerary teeth. J Korean Acad Pediatr Dent, 12:1-5, 1985.
  19. King NM, Tsai JS, Wong HM. : Morphological and numerical characteristics of the Southern Chinese dentitions. Part I : Anomalies in the permanent dentition. Open Anthropol J, 3:54-64, 2010. https://doi.org/10.2174/1874912701003020054
  20. Shankar AA. Koshy AV, Duggal DS, Dandekar RC. : Syndontia with talon cusp : A case report and review of literature. J Oral Maxillofac Pathol, 2:165-9, 2011.
  21. Townsend GC, Richards L, Hughes T, Pinkerton S. : Epigenetic influences may explain dental differences in monozygotic twin pairs. Aust Dent J, 50:95-100, 2005. https://doi.org/10.1111/j.1834-7819.2005.tb00347.x