CELLMED (셀메드)

Cellmed Orthocellular Medicine and Pharmaceutical Association (셀메드 세포교정의약학회)
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A comparison of the effects of dexamethasone-pharmacopuncture and dexamethasone-oral administration based on traditional Korean medicine theory on anaphylactic reaction in mice

  • Kim, Jaehak (Department of Pharmacology, College of Korean Medicine, Kyung Hee University) ;
  • Kang, Doyoung (Department of Pharmacology, College of Korean Medicine, Kyung Hee University) ;
  • Kang, Minsu (Department of Pharmacology, College of Korean Medicine, Kyung Hee University) ;
  • Kang, Bora (Department of Pharmacology, College of Korean Medicine, Kyung Hee University) ;
  • Kang, Eun Byeol (Department of Pharmacology, College of Korean Medicine, Kyung Hee University) ;
  • Kang, Jinseok (Department of Pharmacology, College of Korean Medicine, Kyung Hee University) ;
  • Go, YaeJin (Department of Pharmacology, College of Korean Medicine, Kyung Hee University) ;
  • Ko, Wheehyoung (Department of Pharmacology, College of Korean Medicine, Kyung Hee University) ;
  • Kwak, JaeYoung (Department of Pharmacology, College of Korean Medicine, Kyung Hee University) ;
  • Ku, Hyunjung (Department of Pharmacology, College of Korean Medicine, Kyung Hee University) ;
  • Gwon, Seo Yeon (Department of Pharmacology, College of Korean Medicine, Kyung Hee University) ;
  • Gi, Yumi (Department of Pharmacology, College of Korean Medicine, Kyung Hee University) ;
  • Kim, Gayeon (Department of Pharmacology, College of Korean Medicine, Kyung Hee University) ;
  • Kim, GyeongMuk (Department of Pharmacology, College of Korean Medicine, Kyung Hee University) ;
  • Kim, Kyunghoon (Department of Pharmacology, College of Korean Medicine, Kyung Hee University) ;
  • Kim, Kyuri (Department of Pharmacology, College of Korean Medicine, Kyung Hee University) ;
  • Kim, Dong Hyun (Department of Pharmacology, College of Korean Medicine, Kyung Hee University) ;
  • Kim, MinWoo (Department of Pharmacology, College of Korean Medicine, Kyung Hee University) ;
  • Kim, Min Chae (Department of Pharmacology, College of Korean Medicine, Kyung Hee University) ;
  • Kim, Seongho (Department of Pharmacology, College of Korean Medicine, Kyung Hee University) ;
  • Kim, Seyoon (Department of Pharmacology, College of Korean Medicine, Kyung Hee University) ;
  • Kim, Shilla (Department of Pharmacology, College of Korean Medicine, Kyung Hee University) ;
  • Kim, ShinHyung (Department of Pharmacology, College of Korean Medicine, Kyung Hee University) ;
  • Kim, Young-Jun (Department of Pharmacology, College of Korean Medicine, Kyung Hee University) ;
  • Kim, JongHyeon (Department of Pharmacology, College of Korean Medicine, Kyung Hee University)
  • Received : 2013.07.04
  • Accepted : 2013.08.21
  • Published : 2013.08.31
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Abstract

Pharmacopuncture, or herbal acupuncture, is a new form of therapy derived from combinations of two traditional therapeutic methods, herbal medicine and acupuncture therapy. To compare the efficacy between dexamethasone-pharmacopuncture (DP) and dexamethasone-oral administration (DO), the effect of DP was investigated in murine models. Anti-anaphylactic effects of dexamethasone treatments were investigated in compound 48/80-induced systemic anaphylactic reaction, ear swelling response, and passive cutaneous anaphylaxis (PCA). DP treatment significantly inhibited the compound 48/80-induced systemic anaphylactic reaction, ear swelling response, and PCA. The effects between DP and DO were on a similar level. These results indicate that DP can be used as an alternative method for DO in case of emergency.

Keywords

References

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