DOI QR코드

DOI QR Code

Orthostatic Intolerance Ambulation in Patients Using Patient Controlled Analgesia

  • 투고 : 2012.10.19
  • 심사 : 2013.02.27
  • 발행 : 2013.07.01

초록

Background: Opioid analgesics are widely used to reduce postoperative pain and to enhance post-operative recovery. However, orthostatic intolerance (OI) induced by opioid containing intravenous patient controlled analgesia (IPCA) may hinder postoperative recovery. This study investigated factors that affect OI in patients receiving IPCA for postoperative pain control. Methods: OI was instantly evaluated at the time of first ambulation in 175 patients taking opioid containing IPCA after open and laparoscopic subtotal gastrectomies. Patients were classified as having OI if they experienced dizziness, nausea/vomiting, blurred vision, headache, somnolence and syncope. Factors contributing to OI were assessed with logistic regression analysis. Results: Out of 175 patients, 61 (52.6%) male and 44 (74.6%) female patients experienced OI at the time of first ambulation. The frequency of OI related symptoms were dizziness (97, 55.4%), nausea (46, 26.3%), headache (9, 5.1%), blurred vision (3, 1.7%) and vomiting (2, 1.1%). Significant risk factors for OI were gender (P=0.002) and total amount of opioids administered (P=0.033). Conclusions: The incidence of OI is significantly higher in male than in female patients and is influenced by the opioid dose.

키워드

참고문헌

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피인용 문헌

  1. Postoperative Orthostatic Intolerance and Gender Differences vol.26, pp.4, 2013, https://doi.org/10.3344/kjp.2013.26.4.406
  2. L’intolérance orthostatique postopératoire: malgré un problème périopératoire fréquent, peu de solutions vol.64, pp.1, 2017, https://doi.org/10.1007/s12630-016-0734-7
  3. Orthostatic intolerance in enhanced recovery laparoscopic colorectal resection pp.00015172, 2018, https://doi.org/10.1111/aas.13238
  4. Orthostatic intolerance following hip arthroplasty vol.36, pp.2, 2019, https://doi.org/10.1097/EJA.0000000000000940
  5. Effect of Fentanyl-Based Intravenous Patient-Controlled Analgesia with and without Basal Infusion on Postoperative Opioid Consumption and Opioid-Related Side Effects: A Retrospective Cohort Study vol.13, pp.None, 2013, https://doi.org/10.2147/jpr.s281041