Journal of Gastric Cancer

  • 제13권2호
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  • Pages.117-120
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  • 2013
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  • 2093-582X(pISSN)
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  • 2093-5641(eISSN)
대한위암학회 (The Korean Gastric Cancer Association)
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Adenocarcinoma Occurring in a Gastric Hyperplastic Polyp Treated with Endoscopic Submucosal Dissection

  • Jang, Hye Won (Department of Internal Medicine, Chungnam National University School of Medicine) ;
  • Jeong, Hyun Yong (Department of Internal Medicine, Chungnam National University School of Medicine) ;
  • Kim, Seok Hyun (Department of Internal Medicine, Chungnam National University School of Medicine) ;
  • Kang, Sun Hyung (Department of Internal Medicine, Chungnam National University School of Medicine) ;
  • Seong, Jae Kyu (Department of Internal Medicine, Chungnam National University School of Medicine) ;
  • Song, Kyu Sang (Department of Pathology, Chungnam National University School of Medicine) ;
  • Moon, Hee Seok (Department of Internal Medicine, Chungnam National University School of Medicine)
  • 투고 : 2013.01.21
  • 심사 : 2013.03.17
  • 발행 : 2013.06.30
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초록

Gastric hyperplastic polyps are generally considered benign lesions, although rare cases of adenocarcinoma have been reported. Although, the underlying mechanism of carcinogenesis in gastric hyperplastic polyps is still uncertain, most malignant polyps are seen to originate from dysplastic epithelium rather than from hyperplastic epithelium. Herein, we report the case of a woman diagnosed with adenocarcinoma that originated from a hyperplastic gastric polyp that was successfully removed by endoscopic submucosal dissection. In this case, we observed adenomatous changes around the cancerous component.

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참고문헌

  1. Morais DJ, Yamanaka A, Zeitune JM, Andreollo NA. Gastric polyps: a retrospective analysis of 26,000 digestive endoscopies. Arq Gastroenterol 2007;44:14-17.
  2. Jain R, Chetty R. Gastric hyperplastic polyps: a review. Dig Dis Sci 2009;54:1839-1846. https://doi.org/10.1007/s10620-008-0572-8
  3. Kang HM, Oh TH, Seo JY, Joen TJ, Seo DD, Shin WC, et al. Clinical factors predicting for neoplastic transformation of gastric hyperplastic polyps. Korean J Gastroenterol 2011;58:184-189. https://doi.org/10.4166/kjg.2011.58.4.184
  4. Goddard AF, Badreldin R, Pritchard DM, Walker MM, Warren B; British Society of Gastroenterology. The management of gastric polyps. Gut 2010;59:1270-1276. https://doi.org/10.1136/gut.2009.182089
  5. Snover DC. Benign epithelial polyps of the stomach. Pathol Annu 1985;20:303-329.
  6. Hirasaki S, Suzuki S, Kanzaki H, Fujita K, Matsumura S, Matsumoto E. Minute signet ring cell carcinoma occurring in gastric hyperplastic polyp. World J Gastroenterol 2007;13:5779- 5780.
  7. Varis O, Laxén F, Valle J. Helicobacter pylori infection and fasting serum gastrin levels in a series of endoscopically diagnosed gastric polyps. APMIS 1994;102:759-764. https://doi.org/10.1111/j.1699-0463.1994.tb05231.x
  8. Ljubicić N, Banić M, Kujundzić M, Antić Z, Vrkljan M, Kovacević I, et al. The effect of eradicating Helicobacter pylori infection on the course of adenomatous and hyperplastic gastric polyps. Eur J Gastroenterol Hepatol 1999;11:727-730. https://doi.org/10.1097/00042737-199907000-00008
  9. Ohkusa T, Takashimizu I, Fujiki K, Suzuki S, Shimoi K, Horiuchi T, et al. Disappearance of hyperplastic polyps in the stomach after eradication of Helicobacter pylori. A randomized, clinical trial. Ann Intern Med 1998;129:712-715. https://doi.org/10.7326/0003-4819-129-9-199811010-00006
  10. Veereman Wauters G, Ferrell L, Ostroff JW, Heyman MB. Hyperplastic gastric polyps associated with persistent Helicobacter pylori infection and active gastritis. Am J Gastroenterol 1990;85:1395-1397.
  11. Davaris P, Petraki K, Archimandritis A, Haritopoulos N, Papacharalampous N. Mucosal hyperplastic polyps of the stomach. Do they have any potential to malignancy? Pathol Res Pract 1986;181:385-389. https://doi.org/10.1016/S0344-0338(86)80072-3
  12. Daibo M, Itabashi M, Hirota T. Malignant transformation of gastric hyperplastic polyps. Am J Gastroenterol 1987;82:1016- 1025.
  13. Nogueira AM, Carneiro F, Seruca R, Cirnes L, Veiga I, Machado JC, et al. Microsatellite instability in hyperplastic and adenomatous polyps of the stomach. Cancer 1999;86:1649-1656. https://doi.org/10.1002/(SICI)1097-0142(19991101)86:9<1649::AID-CNCR5>3.0.CO;2-N
  14. Han AR, Sung CO, Kim KM, Park CK, Min BH, Lee JH, et al. The clinicopathological features of gastric hyperplastic polyps with neoplastic transformations: a suggestion of indication for endoscopic polypectomy. Gut Liver 2009;3:271-275. https://doi.org/10.5009/gnl.2009.3.4.271
  15. Orlowska J, Jarosz D, Pachlewski J, Butruk E. Malignant transformation of benign epithelial gastric polyps. Am J Gastroenterol 1995;90:2152-2159.