Journal of information and communication convergence engineering

The Korea Institute of Information and Commucation Engineering (한국정보통신학회)
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Shaded-Mask Filtering for Extended Depth-of-Field Microscopy

  • Received : 2013.03.10
  • Accepted : 2013.04.15
  • Published : 2013.06.30
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Abstract

This paper proposes a new spatial filtering approach for increasing the depth-of-field (DOF) of imaging systems, which is very useful for obtaining sharp images for a wide range of axial positions of the object. Many different techniques have been reported to increase the depth of field. However the main advantage in our method is its simplicity, since we propose the use of purely absorbing beam-shaping elements, which allows a high focal depth with a minimum modification of the optical architecture. In the filter design, we have used the analogy between the axial behavior of a system with spherical aberration and the transverse impulse response of a 1D defocused system. This allowed us the design of a ring-shaded filter. Finally, experimental verification of the theoretical statements is also provided.

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References

  1. S. Zhou and C. Zhou, "Discrete continuous-phase superresolving filters," Optics Letters, vol. 29, no. 23, pp. 2746-2746, 2004. https://doi.org/10.1364/OL.29.002746
  2. M. Yun, L. Liu, J. Sun, and D. Liu, "Three-dimensional superresolution by three-zone complex pupil filters," Journal of the Optical Society of America A, vol. 22, no. 2, pp. 272-277, 2005. https://doi.org/10.1364/JOSAA.22.000272
  3. P. N. Gundu, E. Hack, and P. Rastogi, "Apodized superresolution concepts and simulations," Optics Communications, vol. 249, no. 1-3, pp. 101-107, 2005. https://doi.org/10.1016/j.optcom.2005.01.025
  4. S. F. Pereira and A. S. van de Nes, "Superresolution by means of polarization, phase and amplitude pupil masks," Optics Communications, vol. 234, no. 1-6, pp. 119-124, 2004. https://doi.org/10.1016/j.optcom.2004.02.020
  5. V. F. Canales, D. M. de Juana, and M. P. Cagigal, "Superresolution in compensated telescopes," Optics Letters, vol. 29, no. 9, pp. 935-937, 2004. https://doi.org/10.1364/OL.29.000935
  6. M. T. Caballero, P. Andres, A. Pons, J. Lancis, and M. Martinez-Corral, "Axial resolution in two-color excitation fluorescence microscopy by phase-only binary apodization," Optics Communications, vol. 246, no. 4-6, pp. 313-321, 2005. https://doi.org/10.1016/j.optcom.2004.11.035
  7. D. M. de Juana, J. E. Oti, V. F. Canales, and M. P. Cagigal, "Transverse or axial superresolution in a 4Pi-confocal microscope by phase-only filters," Journal of the Optical Society of America A, vol. 20, no. 11, pp. 2172-2178, 2003. https://doi.org/10.1364/JOSAA.20.002172
  8. L. Liu, C. Liu, W. C. Howe, C. J. R. Sheppard, and N. Chen, "Binary-phase spatial filter for real-time swept-source optical coherence microscopy," Optics Letters, vol. 32, no. 16, pp. 2375-2377, 2007. https://doi.org/10.1364/OL.32.002375
  9. J. Jia, C. Zhou, and L. Liu, "Superresolution technology for reduction of the far-field diffraction spot size in the laser free-space communication system," Optics Communications, vol. 228, no. 4-6, pp. 271-278, 2003. https://doi.org/10.1016/j.optcom.2003.10.011
  10. J. Ojeda-Castaneda, S. Ledesma, and C. M. Gomez-Sarabia, "Hyper Gaussian windows with fractional wavefronts," Photonics Letters of Poland, vol. 5, no. 1, pp. 23-25, 2013.
  11. F. Diaz, F. Goudail, B. Loiseaux, and J. P. Huignard, "Design of a complex filter for depth of focus extension," Optics Letters, vol. 34, no. 8, pp. 1171-1173, 2009. https://doi.org/10.1364/OL.34.001171
  12. M. A. Golub, V. Shurman, and I. Grossinger, "Extended focus diffractive optical element for Gaussian laser beams," Applied Optics, vol. 45, no. 1, pp.144-150, 2006. https://doi.org/10.1364/AO.45.000144
  13. L. Liu, F. Diaz, L. Wang, B. Loiseaux, J. P. Huignard, C. J. R. Sheppard, and N. Chen, "Superresolution along extended depth of focus with binary-phase filter for the Gaussian beam," Journal of the Optical Society of America A, vol. 25, no. 8, pp. 2095-2101, 2008. https://doi.org/10.1364/JOSAA.25.002095
  14. C. J. R. Sheppard, "Binary phase filter with a maximally-flat response," Optics Letters, vol. 36, no. 8, pp.1386-1388, 2011. https://doi.org/10.1364/OL.36.001386
  15. C. J. R. Sheppard and S. Mehta, "Three-level for increased depth of focus and Bessel beam generation," Optics Express, vol. 20, no. 25, pp. 27212-27221, 2012.
  16. C. J. R. Sheppard, "Pupil filter for generation of light sheets," Optics Express, vol. 21, no.5, pp. 6339-6345, 2013. https://doi.org/10.1364/OE.21.006339
  17. A. Castro, J. Ojeda-Castaneda, and A.W. Lohmann, "Bow-tie effect: differential operator," Applied Optics, vol. 45, no. 30, pp. 7878-7884, 2006. https://doi.org/10.1364/AO.45.007878
  18. Z. Zalevsky, A. Shemer, A. Zlotnik, E. B. Eliezer, and E. Marom, "All-optical axial super resolving imaging using a low-frequency binary-phase mask," Optics Express, vol. 14, no. 7, pp. 2631-2643, 2006. https://doi.org/10.1364/OE.14.002631
  19. J. Ojeda-Castaneda, E. Tepichin, and A. Diaz, "Arbitrarily high focal depth with a quasioptimum real and positive transmittance apodizer," Applied Optics, vol. 28, no. 13, pp. 2666-2670, 1989. https://doi.org/10.1364/AO.28.002666
  20. C. M. Hammond Jr, "Apparatus and method for reducing imaging errors in imaging systems having an extended depth of field," US patent 6097856, 2000.
  21. D. Miller and E. Blanco, "System and method for increasing the depth of focus of the human eye," US patent 6554424, 2003.
  22. E. Ben-Eliezer, E. Marom, N. Konforti, and Z. Zalevsky, "Experimental realization of an imaging system with an extended depth of field," Applied Optics, vol. 44, no. 14, pp. 2792-2798, 2005. https://doi.org/10.1364/AO.44.002792
  23. C. J. R. Sheppard and M. Gu, "Imaging by a high aperture optical system," Journal of Modern Optics, vol. 40, no. 8, pp. 1631-1651, 1993. https://doi.org/10.1080/09500349314551641
  24. P. Debye, "Der lichtdruck auf kugeln von beliebigem material," Annalen der Physik, vol. 335, no. 11, pp. 57-136, 1909. https://doi.org/10.1002/andp.19093351103
  25. M. Born and E. Wolf, Principles of Optics, 7th ed. New York, NY: Cambridge University Press, 1999.
  26. C. J. R. Sheppard and H. J. Matthews, "Imaging in high-aperture optical system," Journal of the Optical Society of America A, vol. 4, no. 8, pp. 1354-1360, 1987. https://doi.org/10.1364/JOSAA.4.001354
  27. I. Escobar, G. Saavedra, M. Martinez-Corral, and J. Lancis, "Reduction of the spherical aberration effect in high-numerical-aperture optical scanning instruments," Journal of the Optical Society of America A, vol. 23, no. 12, pp. 3150-3155, 2006. https://doi.org/10.1364/JOSAA.23.003150
  28. M. Martinez-Corral and G. Saavedra, "The resolution challenge in 3D optical microscopy," Progress in Optics, vol. 53, pp. 1-68, 2009. https://doi.org/10.1016/S0079-6638(08)00201-1
  29. I. Escobar, E. Sanchez-Ortiga, G. Saavedra, and M. Martinez-Corral, "New analytical tools for evaluation of spherical aberration in optical microscopy," in Optical Fluorescence Microscopy: from the Spectral to the Nano Dimension, Heidelberg, Germany: Springer, pp. 85-99, 2011.
  30. T. Wilson and A. R. Carlini, "Three-dimensional imaging in confocal imaging-systems with finite sized detectors," Journal of Microscopy, vol. 149, no. 1, pp. 51-66, 1988. https://doi.org/10.1111/j.1365-2818.1988.tb04561.x
  31. S. Kimura and C. Munakata, "Dependence of 3-D optical transfer functions in the pinhole radius in a fluorescent confocal optical microscope," Applied Optics, vol. 29, no. 20, pp. 3007-3011, 1990. https://doi.org/10.1364/AO.29.003007
  32. M. Gu and C. J. R. Sheppard, "Effects of a finite-sized pinhole on 3D image formation in confocal two-photon fluorescence microscopy," Journal of Modern Optics, vol. 40, no. 10, pp. 2009-2024, 1993. https://doi.org/10.1080/09500349314552011
  33. R. Gauderon and C. J. R. Sheppard, "Effect of a finite-size pinhole on noise performance in single-, two-, and three-photon confocal fluorescence microscopy," Applied Optics, vol. 38, no. 16, pp. 3562-3565, 1999. https://doi.org/10.1364/AO.38.003562

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