Korean Circulation Journal

The Korean Society of Cardiology (대한심장학회)
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Severe Pulmonary Hypertension in Primary Sj$\ddot{o}$gren's Syndrome

  • Hwang, Ji-An (Division of Cardiology, Department of Internal Medicine, Inje University College of Medicine, Cardiovascular Research Institute, Busan Paik Hospital) ;
  • Yang, Tae-Hyun (Division of Cardiology, Department of Internal Medicine, Inje University College of Medicine, Cardiovascular Research Institute, Busan Paik Hospital) ;
  • Lee, Ji-Young (Division of Cardiology, Department of Internal Medicine, Inje University College of Medicine, Cardiovascular Research Institute, Busan Paik Hospital) ;
  • Koo, Dong-Wan (Division of Cardiology, Department of Internal Medicine, Inje University College of Medicine, Cardiovascular Research Institute, Busan Paik Hospital) ;
  • Choi, In Suk (Cardiology Division, Department of Internal Medicine, Gachon University) ;
  • Cho, Sun-Young (Division of Cardiology, Department of Internal Medicine, Inje University College of Medicine, Cardiovascular Research Institute, Busan Paik Hospital) ;
  • Kim, Min-Sung (Division of Cardiology, Department of Internal Medicine, Inje University College of Medicine, Cardiovascular Research Institute, Busan Paik Hospital)
  • Published : 2013.07.30
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Abstract

A 65 year-old female with a history of xerostomia and xerophthalmia was presented with dyspnea on exertion (New York Heart Association class III). Echocardiography and cardiac catheterization demonstrated severe pulmonary hypertension (PH). Laboratory examinations showed positive anti-nuclear and anti-Ro/SS-A antibodies. Schirmer's test was positive and salivary gland scintigraphy revealed severely decreased tracer uptakes in both parotid and submandibular glands. By excluding other possible causes of PH during further examinations, she was diagnosed with severe PH associated with primary Sj$\ddot{o}$gren's syndrome. Her dyspnea symptom was much improved with endothelin receptor antagonist and azathioprine.

Keywords

References

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