Korean Circulation Journal

  • 제43권5호
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  • Pages.340-342
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  • 2013
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  • 1738-5520(pISSN)
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  • 1738-5555(eISSN)
대한심장학회 (The Korean Society of Cardiology)
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Acquired Long QT Syndrome Manifesting with Torsades de Pointes in a Patient with Panhypopituitarism due to Radiotherapy

  • Kang, Dae Gil (Division of Cardiology, Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University Medical Center) ;
  • Kim, Sung Eun (Division of Cardiology, Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University Medical Center) ;
  • Park, Myoung Soo (Division of Cardiology, Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University Medical Center) ;
  • Kim, Eun Jung (Division of Cardiology, Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University Medical Center) ;
  • Lee, Jun Hee (Division of Cardiology, Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University Medical Center) ;
  • Park, Dae Gyun (Division of Cardiology, Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University Medical Center) ;
  • Han, Kyoo Rok (Division of Cardiology, Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University Medical Center) ;
  • Oh, Dong Jin (Division of Cardiology, Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University Medical Center)
  • 발행 : 2013.05.30
⟨ 이전 논문 다음 논문 ⟩

초록

We describe a 64-year-old male patient with panhypopituitarism who experienced polymorphic ventricular tachycardia (VT) associated with long QT intervals. The panhypopituitarism developed as a sequelae of radiation therapy administered 20 years prior to his current presentation and was recently aggravated by urinary tract infection with sepsis. In this case, polymorphic VT was resistant to conventional therapy (including magnesium infusion), and QT prolongation and T wave inversion were normalized after the administration of steroid and thyroid hormones. Thyroid hormone is generally known to be associated with torsades de pointes (TdP), but steroid or other hormones may also provoke TdP. Hormonal disorders should be considered as a cause of polymorphic VT with long QT intervals. Some arrhythmias can be life-threatening, and they can be prevented with supplementation of the insufficient hormone.

키워드

참고문헌

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  1. Long-Standing Undiagnosed Sheehan Syndrome Presenting as Polymorphic and Monomorphic Ventricular Tachycardia: A Case Series of 2 Patients vol.20, pp.11, 2013, https://doi.org/10.4158/ep14233.cr
  2. Adrenal insufficiency causes life-threatening arrhythmia with prolongation of QT interval vol.31, pp.None, 2016, https://doi.org/10.1007/s00380-015-0660-6
  3. Ventricular fibrillation and long-QT syndrome due to panhypopituitarism : vol.18, pp.10, 2013, https://doi.org/10.2459/jcm.0000000000000531
  4. Polymorphic Ventricular Tachycardia with QT Interval Prolongation Due to a Brain Tumor vol.60, pp.16, 2021, https://doi.org/10.2169/internalmedicine.6635-20