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Acute Stent Thrombosis and Heparin Induced Thrombocytopenia: Another Manifestation of Kounis Syndrome?

  • Kounis, Nicholas G. (Department of Medical Sciences Patras Highest Institute of Education and Technology, Patras, Greece and Department of Cardiology, Saint Andrews State General Hospital) ;
  • Soufras, George D. (Department of Medical Sciences Patras Highest Institute of Education and Technology, Patras, Greece and Department of Cardiology, Saint Andrews State General Hospital) ;
  • Almpanis, George (Department of Medical Sciences Patras Highest Institute of Education and Technology, Patras, Greece and Department of Cardiology, Saint Andrews State General Hospital) ;
  • Tsigkas, Grigorios (Department of Medical Sciences Patras Highest Institute of Education and Technology, Patras, Greece and Department of Cardiology, Saint Andrews State General Hospital) ;
  • Mazarakis, Andreas (Department of Medical Sciences Patras Highest Institute of Education and Technology, Patras, Greece and Department of Cardiology, Saint Andrews State General Hospital)
  • Published : 2013.04.30

Abstract

Keywords

References

  1. Kounis NG. Kounis syndrome should be considered the culprit cause of the most feared stent thrombosis. J Am Coll Cardiol 2011;58:885;author reply 886-7.
  2. Kounis NG, Giannopoulos S, Tsigkas GG, Goudevenos J. Eosinophilic responses to stent implantation and the risk of Kounis hypersensitivity associated coronary syndrome. Int J Cardiol 2012;156:125-32. https://doi.org/10.1016/j.ijcard.2011.05.052
  3. Shin HW, Yoon HJ, Choi SW, et al. Acute stent thrombosis and heparin induced thrombocytopenia in a patient with ST-segment elevation myocardial infarction. Korean Circ J 2012;42:646-9. https://doi.org/10.4070/kcj.2012.42.9.646
  4. Kounis NG, Mazarakis A, Tsigkas G, Giannopoulos S, Goudevenos J. Kounis syndrome: a new twist on an old disease. Future Cardiol 2011;7:805-24. https://doi.org/10.2217/fca.11.63
  5. Vakil NH, Kanaan AO, Donovan JL. Heparin-induced thrombocytopenia in the pediatric population: a review of current literature. J Pediatr Pharmacol Ther 2012;17:12-30.
  6. Howell WH, Holt E. Two new factors in blood coagulation-heparin and pro-antithrombin. Am J Physiol 1918;47:328-41.
  7. Arepally GM, Mayer IM. Antibodies from patients with heparin-induced thrombocytopenia stimulate monocytic cells to express tissue factor and secrete interleukin-8. Blood 2001;98:1252-4. https://doi.org/10.1182/blood.V98.4.1252
  8. Dawes J, Pumphrey CW, McLaren KM, Prowse CV, Pepper DS. The in vivo release of human platelet factor 4 by heparin. Thromb Res 1982;27:65-76. https://doi.org/10.1016/0049-3848(82)90279-1
  9. Chong BH. Heparin-induced thrombocytopenia. Br J Haematol 1995;89:431-9. https://doi.org/10.1111/j.1365-2141.1995.tb08346.x

Cited by

  1. COVID-19 Disease, Women’s Predominant Non-Heparin Vaccine-Induced Thrombotic Thrombocytopenia and Kounis Syndrome: A Passepartout Cytokine Storm Interplay vol.9, pp.8, 2013, https://doi.org/10.3390/biomedicines9080959