Korean Circulation Journal

The Korean Society of Cardiology (대한심장학회)
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The Prognostic Implication of Metabolic Syndrome in Patients with Heart Failure

  • Yoon, Hyun Ju (Department of Cardiology, Chonnam National University Hospital) ;
  • Ahn, Youngkeun (Department of Cardiology, Chonnam National University Hospital) ;
  • Kim, Kye Hun (Department of Cardiology, Chonnam National University Hospital) ;
  • Park, Jong Chun (Department of Cardiology, Chonnam National University Hospital) ;
  • Choi, Dong-Ju (Department of Cardiology, Seoul National University College of Medicine, Bundang Hospital) ;
  • Han, Seongwoo (Department of Cardiology, Hallym University College of Medicine, Kangnam Sacred Heart Hospital) ;
  • Jeon, Eun-Seok (Department of Cardiology, Sungkyunkwan University College of Medicine, Samsung Medical Center) ;
  • Cho, Myung-Chan (Department of Cardiology, Chungbuk National University College of Medicine) ;
  • Kim, Jae-Joong (Department of Cardiology, University of Ulsan College of Medicine, Asan Medical Center) ;
  • Yoo, Byung-Su (Department of Cardiology, Yonsei University Wonju Christian Hospital) ;
  • Shin, Mi-Seung (Department of Cardiology, Gachon University Gil Hospital) ;
  • Seong, In-Whan (Department of Cardiology, Chungnam National University Hospital) ;
  • Kang, Seok-Min (Department of Cardiology, Yonsei University Severance Hospital) ;
  • Kim, Yung-Jo (Department of Cardiology, Yeungnam University College of Medicine) ;
  • Kim, Hyung Seop (Department of Cardiology, Keimyung University College of Medicine) ;
  • Chae, Shung Chull (Department of Cardiology, Kyungpook National University College of Medicine) ;
  • Oh, Byung-Hee (Department of Cardiology, Seoul National University College of Medicine) ;
  • Lee, Myung-Mook (Department of Cardiology, Dongguk University College of Medicine, Ilsan Hospital) ;
  • Ryu, Kyu-Hyung (Department of Cardiology, Hallym University College of Medicine, Dongtan Sacred Heart Hospital) ;
  • The Korea HF Registry, The Korea HF Registry (The Korea HF Registry)
  • Published : 2013.02.28
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Abstract

Background and Objectives: Metabolic syndrome (MetS) increases the risk of heart failure (HF). The purpose of this study was to identify the prevalence of MetS in patients with HF and determine the syndrome's association with HF in clinical and laboratory parameters. Subjects and Methods: A total of 3200 HF patients ($67.6{\pm}14.5$ years) enrolled in a nationwide prospective Korea HF Registry between Jan. 2005 and Oct. 2009. Patients were divided into two groups according to the presence or absence of MetS at admission: group I (presence, n=1141) and group II (absence, n=2059). Results: The prevalence of MetS was 35.7% across all subjects and was higher in females (56.0%). The levels of white blood cells, platelets, creatinine, glucose, and cholesterol were significantly higher in group I than in group II. Left ventricular dimension and volume was smaller and ejection fraction was higher in group I than in group II. An ischemic cause of HF was more frequent in group I. The rates of valvular and idiopathic cause were lower in group I than in group II. The rate of mortality was lower in group I than in group II (4.9% vs. 8.3%, p<0.001). Conclusion: Despite the increased cardiovascular risks in MetS, MetS was found to be associated with decreased mortality in HF.

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References

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