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Four Cases of Metastasectomy for Pulmonary Metastasis of Nasopharyngeal Carcinoma

비인두암의 폐전이 환자의 폐전이절제술 시행 4예

  • Lee, Hyo Jung (Department of Hematology-Oncology, Ajou University School of Medicine) ;
  • Jeon, Ja Young (Department of Hematology-Oncology, Ajou University School of Medicine) ;
  • Han, Jae Ho (Department of Pathology, Ajou University School of Medicine) ;
  • Sun, Joo Sung (Department of Radiology, Ajou University School of Medicine) ;
  • Choi, Ho (Department of Thoracic Surgery Ajou University School of Medicine) ;
  • Choi, Jin-Hyuk (Department of Hematology-Oncology, Ajou University School of Medicine) ;
  • Ahn, Mi Sun (Department of Hematology-Oncology, Ajou University School of Medicine)
  • 이효정 (아주대학교 의과대학 종양혈액내과학교실) ;
  • 전자영 (아주대학교 의과대학 종양혈액내과학교실) ;
  • 한재호 (아주대학교 의과대학 병리학교실) ;
  • 선주성 (아주대학교 의과대학 영상의학교실) ;
  • 최호 (아주대학교 의과대학 흉부외과학교실) ;
  • 최진혁 (아주대학교 의과대학 종양혈액내과학교실) ;
  • 안미선 (아주대학교 의과대학 종양혈액내과학교실)
  • Published : 2013.01.01

Abstract

Nasopharyngeal carcinoma is a rare cancer with a relatively poor prognosis because patients tend to be diagnosed in the advanced stage. Distant metastases have been recognized to be a major cause of treatment failure. However, because long-term survival has been reported in patients with lung metastasis alone, an aggressive approach to treatment for this group of patients should be considered. We report four cases of metastasectomy for pulmonary metastasis of nasopharyngeal carcinoma. The metastatic lesions were confined to the lung with or without regional lymph nodes. The patients underwent a pulmonary metastasectomy following adjuvant chemotherapy with or without radiotherapy, and all patients are now disease-free.

비인두암은 국소적으로 방사선요법에 반응을 잘하여 완전관해를 보이는 경우가 많지만 원격전이, 특히 폐로의 전이가 잘 일어나는 암이다. 폐 단독 전이가 있을 때 비교적 양호한 예후를 보이므로 적극적인 치료가 중요하지만 폐전이 절제술 또는 동시 항암화학방사선요법의 역할에 대해서는 정립된 표준요법이 없다. 두경부암 등을 포함한 여러 고형종양에서 폐전이절제술이 효과가 있다는 보고들이 있으므로 비인두암의 폐전이 환자들에서도 적극적인 폐전이절제술을 고려해 볼 수 있으며, 환자군을 잘 선별하여 시행했을 때 좋은 예후를 기대할 수 있을 것으로 생각된다. 저자들은 비인두암의 폐전이 환자들에서 폐전이절제술을 특별한 합병증 없이 시행하였고, 보조 항암화학요법 후 현재까지 무병상태를 보인 예들을 보고하는 바이다.

Keywords

References

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