DOI QR코드

DOI QR Code

일차성 사구체신염의 국내발병 현황

Current Status of Primary Glomerulonephritis

  • 채동완 (서울대학교 의과대학 내과학교실, 분당서울대병원 신장내과)
  • Chae, Dong-Wan (Division of Nephrology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine)
  • 발행 : 2013.01.01

초록

Recent change in major indication for renal biopsy from nephrotic syndrome to asymptomatic urinary abnormality (AU) in Korea makes IgA nephropathy the most common biopsy- confirmed glomerulonephritis (GN). Beside from the most common manifestation of AU, a significant portion (22%) of IgA nephropathy (IgAN) patient revealed the nephrotic-range proteinuria. About 1/3 of patients with minimal change disease (MCD), membranous nephropathy (MN) and focal segmental glomerulosclerosis (FSGS) presented with AU. In elderly patient (> 60 years), the proportion of cresentic glomerulonephritis, MN, and FSGS increased, while the prevalence of IgAN decreased compared to younger patients. MCD showed no change based on old age. GN was the third most common cause of ESRD constituting 11-15% of cases. ESRD patients from GN start dialysis younger and live longer on dialysis compared to diabetic and hypertensive patients in Korea.

키워드

참고문헌

  1. McGrogan A, Franssen CF, de Vries CS. The incidence of primary glomerulonephritis worldwide: a systematic review of the literature. Nephrol Dial Transplant 2011;26:414-430. https://doi.org/10.1093/ndt/gfq665
  2. McQuarrie EP, Mackinnon B, Young B, et al. Centre variation in incidence, indication and diagnosis of adult native renal biopsy in Scotland. Nephrol Dial Transplant 2009;24:1524-1528. https://doi.org/10.1093/ndt/gfn677
  3. Choi IJ, Jeong HJ, Han DS, et al. An analysis of 4,514 cases of renal biopsy in Korea. Yonsei Med J 2001;42:247-254. https://doi.org/10.3349/ymj.2001.42.2.247
  4. Oh YK, Ahn KR, Lee SJ, et al. Adult glomerulonephritis in Korea: analysis of 2,001 cases. Korean J Nephrol 1996;15:289-299.
  5. Johnson RJ, Hurtado A, Merszei J, Rodriguez-Iturbe B, Feng L. Hypothesis: dysregulation of immunologic balance resulting from hygiene and socioeconomic factors may influence the epidemiology and cause of glomerulonephritis worldwide. Am J Kidney Dis 2003;42:575-581. https://doi.org/10.1016/S0272-6386(03)00801-1
  6. Kim KH, Son YK, Lee SM, An WS, Kim SE, Rha SH. Prevalence of primary glomerulonephritis - a single center analysis. Korean J Nephrol 2011;30:498-505.
  7. Yokoyama H, Sugiyama H, Sato H, et al. Renal disease in the elderly and the very elderly Japanese: analysis of the Japan Renal Biopsy Registry (J-RBR). Clin Exp Nephrol 2012;16:903-920. https://doi.org/10.1007/s10157-012-0673-8
  8. Moutzouris DA, Herlitz L, Appel GB, et al. Renal biopsy in the very elderly. Clin J Am Soc Nephrol 2009;4:1073-1082. https://doi.org/10.2215/CJN.00990209
  9. ESRD Registry Committee. Current Renal Replacement Therapy in Korea. 32nd Congress of The Korean Society of Nephrology. Korean Society of Nephrology, 2012.
  10. United States Renal Data System (USRDS) Coordinating Center. Annual report of United Renal Data System [Internet]. Minneapolis, MN: United States Renal Data System (USRDS) Coordinating Center, 2012 [cited 2012. Dec 20]. Available from: http://www.usrds.org.
  11. Yamagata K, Takahashi H, Suzuki S, et al. Age distribution and yearly changes in the incidence of ESRD in Japan. Am J Kidney Dis 2004;43:433-443. https://doi.org/10.1053/j.ajkd.2003.11.005
  12. Yang WC, Hwang SJ; Taiwan Society of Nephrology. Incidence, prevalence and mortality trends of dialysis end-stage renal disease in Taiwan from 1990 to 2001: the impact of national health insurance. Nephrol Dial Transplant 2008;23:3977-3982. https://doi.org/10.1093/ndt/gfn406
  13. Yamagata K, Iseki K, Nitta K, et al. Chronic kidney disease perspectives in Japan and the importance of urinalysis screening. Clin Exp Nephrol 2008;12:1-8. https://doi.org/10.1007/s10157-007-0010-9
  14. Hsu CY. Does non-malignant hypertension cause renal insufficiency? evidence-based perspective. Curr Opin Nephrol Hypertens 2002;11:267-272. https://doi.org/10.1097/00041552-200205000-00001
  15. Layton JB, Hogan SL, Jennette CE, et al. Discrepancy between Medical Evidence Form 2728 and renal biopsy for glomerular diseases. Clin J Am Soc Nephrol 2010;5:2046-2052. https://doi.org/10.2215/CJN.03550410

피인용 문헌

  1. New classification of membranoproliferative glomerulonephritis: a good start but a long way to go vol.33, pp.4, 2013, https://doi.org/10.1016/j.krcp.2014.10.005
  2. Small Red Blood Cell Fraction on the UF-1000i Urine Analyzer as a Screening Tool to Detect Dysmorphic Red Blood Cells for Diagnosing Glomerulonephritis vol.39, pp.3, 2013, https://doi.org/10.3343/alm.2019.39.3.271
  3. Patterns in renal diseases diagnosed by kidney biopsy: A single-center experience vol.39, pp.1, 2020, https://doi.org/10.23876/j.krcp.19.077