The Korean journal of internal medicine

  • 제28권4호
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  • Pages.403-407
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  • 2013
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  • 1226-3303(pISSN)
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  • 2005-6648(eISSN)
대한내과학회 (The Korean Association of Internal Medicine)
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Vaccines against Coccidioides

  • Yoon, Hee Jung (Division of Infectious Diseases, Department of Internal Medicine, Eulji University Hospital) ;
  • Clemons, Karl V. (California Institute for Medical Research, Stanford University School of Medicine)
  • 발행 : 2013.07.01
⟨ 이전 논문 다음 논문 ⟩

초록

Vaccines against fungal diseases are gaining attention because of their growing impact on modern medicine. Development of these vaccines should incorporate immunological tools that integrate with or replace chemotherapy to minimize antibiotic use and consequent resistance. In this review, we evaluate the current developmental status of fungal vaccines against coccidioidomycosis. There is a need for a vaccine that sufficiently prevents disease, without eradicating the fungus, by neutralizing adhesions and enzymes or other low penetrance virulence traits.

키워드

참고문헌

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피인용 문헌

  1. Adjuvants and delivery systems for antifungal vaccines: Current state and future developments vol.53, pp.1, 2013, https://doi.org/10.1093/mmy/myu045
  2. Linear Epitopes of Paracoccidioides brasiliensis and Other Fungal Agents of Human Systemic Mycoses As Vaccine Candidates vol.8, pp.None, 2017, https://doi.org/10.3389/fimmu.2017.00224
  3. Methods of Controlling Invasive Fungal Infections Using CD8 + T Cells vol.8, pp.None, 2017, https://doi.org/10.3389/fimmu.2017.01939
  4. Future Research Priorities in Fungal Resistance vol.216, pp.3, 2013, https://doi.org/10.1093/infdis/jix103
  5. Genetic Vaccination as a Flexible Tool to Overcome the Immunological Complexity of Invasive Fungal Infections vol.12, pp.None, 2013, https://doi.org/10.3389/fmicb.2021.789774