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Perforated Early Gastric Cancer: Uncommon and Easily Missed a Case Report and Review of Literature

  • Lim, Raymond Hon Giat (Department of Surgery, Singapore National University Hospital) ;
  • Tay, Clifton Ming (Yong Loo Lin School of Medicine, National University of Singapore) ;
  • Wong, Benjamin (Department of Pathology, Singapore National University Hospital) ;
  • Chong, Choon Seng (Department of Surgery, Singapore National University Hospital) ;
  • Kono, Koji (Department of Surgery, Singapore National University Hospital) ;
  • So, Jimmy Bok Yan (Department of Surgery, Singapore National University Hospital) ;
  • Shabbir, Asim (Department of Surgery, Singapore National University Hospital)
  • 투고 : 2012.09.18
  • 심사 : 2012.12.01
  • 발행 : 2013.03.30

초록

Gastric carcinoma rarely presents as a perforation, but when it does, is perceived as advanced disease. The majority of such perforations are Stage III/IV disease. A T1 gastric carcinoma has never been reported to perforate spontaneously in English literature. We present a 56 year-old Chinese male who presented with a perforated gastric ulcer. Intra-operatively, there was no suspicion of malignancy. At operation, an open omental patch repair was performed. Post-operative endoscopy revealed a macroscopic Type 0~III tumour and from the ulcer edge biopsy was reported as adenocarcinoma. Subsequently, the patient underwent open subtotal gastrectomy and formal D2 lymphadenectomy. The final histopathology report confirms T1b N0 disease. The occurrence of a perforated early gastric cancer reemphasises the need for vigilance, including intra-operative frozen section and/or biopsy, as well as routine post-operative endoscopy for all patients.

키워드

참고문헌

  1. Adachi Y, Mori M, Maehara Y, Matsumata T, Okudaira Y, Sugimachi K. Surgical results of perforated gastric carcinoma: an analysis of 155 Japanese patients. Am J Gastroenterol 1997;92:516-518.
  2. Roviello F, Rossi S, Marrelli D, De Manzoni G, Pedrazzani C, Morgagni P, et al. Perforated gastric carcinoma: a report of 10 cases and review of the literature. World J Surg Oncol 2006;4:19. https://doi.org/10.1186/1477-7819-4-19
  3. Mahar AL, Brar SS, Coburn NG, Law C, Helyer LK. Surgical management of gastric perforation in the setting of gastric cancer. Gastric Cancer 2012;15 Suppl 1:S146-152. https://doi.org/10.1007/s10120-011-0095-4
  4. Kitakado Y, Tanigawa N, Muraoka R. A case report of perforated early gastric cancer. Nihon Geka Hokan 1997;66:86-90.
  5. Gertsch P, Yip SK, Chow LW, Lauder IJ. Free perforation of gastric carcinoma. Results of surgical treatment. Arch Surg 1995;130:177-181. https://doi.org/10.1001/archsurg.1995.01430020067011
  6. Japanese Gastric Cancer Association. Japanese classification of gastric carcinoma: 3rd English edition. Gastric Cancer 2011;14:101-112. https://doi.org/10.1007/s10120-011-0041-5
  7. So JB, Yam A, Cheah WK, Kum CK, Goh PM. Risk factors related to operative mortality and morbidity in patients undergoing emergency gastrectomy. Br J Surg 2000;87:1702-1707. https://doi.org/10.1046/j.1365-2168.2000.01572.x
  8. Miura T, Ishii T, Shimoyama T, Hirano T, Tomita M. Surgical treatment of perforated gastric cancer. Dig Surg 1985;2:200-204. https://doi.org/10.1159/000171705
  9. Cuschieri A, Weeden S, Fielding J, Bancewicz J, Craven J, Joypaul V, et al. Patient survival after D1 and D2 resections for gastric cancer: long-term results of the MRC randomized surgical trial. Surgical Co-operative Group. Br J Cancer 1999;79:1522-1530. https://doi.org/10.1038/sj.bjc.6690243
  10. Tan KK, Quek TJ, Wong N, Li KK, Lim KH. Emergency surgery for perforated gastric malignancy: an institution's experience and review of the literature. J Gastrointest Oncol 2011;2:13-18.

피인용 문헌

  1. Surgical outcome evaluation of perforated gastric cancer: from the aspects of both acute care surgery and surgical oncology vol.52, pp.12, 2017, https://doi.org/10.1080/00365521.2017.1369562
  2. A Perforated Gastric Carcinoma: A Single-Center Experience vol.104, pp.5, 2019, https://doi.org/10.9738/intsurg-d-17-00069.1