Journal of The Korean Society of Clinical Toxicology (대한임상독성학회지)
- Volume 11 Issue 2
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- Pages.127-129
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- 2013
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- 1738-1320(pISSN)
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- 2508-6332(eISSN)
A Case of Seizures after Zolpidem Withdrawal
고용량 졸피뎀 복용 중단 이후 발생한 경련발작 1례
- Moon, Hyung Jun (Department of Emergency Medicine, Soon Chun Hyang University College of Medicine) ;
- Lee, Jung Won (Department of Emergency Medicine, Soon Chun Hyang University College of Medicine) ;
- Yoo, Byeong Dae (Department of Emergency Medicine, Soon Chun Hyang University College of Medicine)
- Received : 2013.07.23
- Accepted : 2013.08.21
- Published : 2013.12.31
Abstract
The imidazopyridine, zolpidem, a non-benzodiazepine hypnotic drug, is widely-prescribed for insomnia. It is regarded as a good alternative to benzodiazepine because of the reduced possibility for abuse and development of dependence. However, more recently, due to the reduced possibility for abuse and development of dependence, it is regarded as a good alternative to benzodiazepine. adverse effects of zolpidem have been recognized. The objective of this report is to provide information on the potential for occurrence of benzodiazepine-like withdrawal seizure in patients who chronically take zolpidem continually. We present and discuss a case of seizure after sudden interruption of the protracted use of an abusively high dose of zolpidem. Zolpidem may not be the ideal drug for longterm pharmacotherapeutic management of insomnia. Clinicians should administer zolpidem at a low-dose for a short period of time for prevention of drug abuse and dependence and the potential for occurrence of benzodiazepine- like withdrawal seizure.