Preventive Nutrition and Food Science

  • 제18권1호
  • /
  • Pages.38-44
  • /
  • 2013
  • /
  • 2287-1098(pISSN)
  • /
  • 2287-8602(eISSN)
한국식품영양과학회 (The Korean Society of Food Science and Nutrition)
권호 표지
DOI QR코드

DOI QR Code

Effect of Polyopes lancifolia Extract on Oxidative Stress in Human Umbilical Vein Endothelial Cells Induced by High Glucose

  • Min, Seong Won (Department of Food Science and Nutrition, Pusan National University) ;
  • Han, Ji Sook (Department of Food Science and Nutrition, Pusan National University)
  • 투고 : 2012.12.11
  • 심사 : 2013.02.01
  • 발행 : 2013.03.31
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

The protective effect of Polyopes lancifolia extract on high glucose-induced oxidative stress was investigated using human umbilical vein endothelial cells (HUVECs). High concentration of glucose (30 mM) treatment induced HUVECs cell death, but Polyopes lancifolia extract, at concentrations of 25, 50, and $100{\mu}g/mL$, protected cells from high glucose-induced damage. Furthermore, thiobarbituric acid reactive substances, intracellular reactive oxygen species, and nitric oxide levels increased by high glucose treatment were effectively decreased by treatment with Polyopes lancifolia extract in a dose-dependent manner. Also, Polyopes lancifolia extract treatment reduced the overexpressions of inducible nitric oxide synthase, cyclooxygenase-2, and nuclear factor-kappa B proteins activation that was induced by high glucose in HUVECs. These results indicate that Polyopes lancifolia extract is a potential therapeutic material that will reduce the damage caused by high glucose-induced-oxidative stress associated with diabetes.

키워드

참고문헌

  1. Corry DB, Tuck ML. 2000. Protection from vascular risk in diabetic by pretension. Curr Hypertens Rep 2: 154-159. https://doi.org/10.1007/s11906-000-0075-2
  2. Krentz AJ, Clough G, Byren CD. 2007. Interaction between microvascular and macrovascular disease in diabetes: pathophysiology and therapeutic implications. Diabetes Obes Metab 9: 781-791. https://doi.org/10.1111/j.1463-1326.2007.00670.x
  3. World Health Organization (WHO). Update 2012. http://www.who.int/mediacentre/factsheets/fs312/en/.
  4. Kaplan M, Aviram M, Hayek T. 2012. Oxidative stress and macrophage foam cell formation during diabetes mellitusinduced atherogenesis: Role of insulin therapy. Pharmacol Ther 136: 175-185. https://doi.org/10.1016/j.pharmthera.2012.08.002
  5. Diabetes Control and Complications Trial Research Group. 1993. The effect of intensive treatment of diabetes on the debelopment and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 329: 977-986. https://doi.org/10.1056/NEJM199309303291401
  6. Hiramatsu K, Arimori S. 1998. Increased superoxide production by mononuclear cells of patients with hypertryglycerdemia and diabetes. Diabetes 37: 832-837.
  7. Van Dam PS, Van Asbeck BS, Van Oirschot JF, Biessels GJ, Hamers FP, Marx JJ. 2001. Glutathione and alpha-lipoate in diabetic rate: nerve function, blood flow and oxidative state. Eur J Clin Invest 31: 417-424. https://doi.org/10.1046/j.1365-2362.2001.00832.x
  8. Feldman EF. 2003. Oxidative stress and diabetic neuropathy: a new understanding of an old problem. J Clin Invest 111: 431-433. https://doi.org/10.1172/JCI200317863
  9. Park MJ, Song YS, Han JS. 2006. Protective effects of the BuOH fraction from Laminaria japonica extract on high glucose-induced oxidative stress in human umbilical vein endothelial cells. J Food Sci Nutr 11: 94-99. https://doi.org/10.3746/jfn.2006.11.2.094
  10. Tsuneki H, Sekizaki N, Suzuki T, Kobayashi S, Wada T, Okamoto T, Kimura I, Sasaoka T. 2007. Coenzyme Q10 prevents high glucose-induced oxidative stress in human umbilical vein endothelial cells. Eur J Pharmacol 566: 1-10. https://doi.org/10.1016/j.ejphar.2007.03.006
  11. Dewanjee S, Das AK, Sahu R, Gangopadhyay M. 2009. Antidiabetic activity of Diospyros peregrine fruit: effect on hyperglycemia, hyperlipidemia and augmented oxidative stress in experimental type 2 diabetes. Food Chem Toxicol 47:2679-2685. https://doi.org/10.1016/j.fct.2009.07.038
  12. Saini AK, Arun KHS, Sharma SS. 2007. Preventive and curative effect of edaravone on nerve functions and oxidative stress in experimental diabetic neuropathy. Eur J Pharmacol 568: 164-172. https://doi.org/10.1016/j.ejphar.2007.04.016
  13. Giugliano D, Ceriello A, Paolisso G. 1996. Oxidative stress and diabetic vascular complications. Diabetes Care 19: 257-267. https://doi.org/10.2337/diacare.19.3.257
  14. Baynes JW, Thorpe SR. 1999. Role of oxidative stress in diabetic complications: a new perspective on an old paradigm. Diabetes 48: 1-9. https://doi.org/10.2337/diabetes.48.1.1
  15. Zanetti M, Zwacka R, Engelhardt J, Katusic Z, O'Brien T. 2001. Superoxide anions and endothelial cell proliferation in normoglycemia and hyperglycemia. Arterioscler Thromb Vasc Biol 21: 195-200. https://doi.org/10.1161/01.ATV.21.2.195
  16. Mineur F, Clerck OD, Roux AL, Maggs CA, Verlaque M. 2010. Polyopes lancifolius (Halymeniales, Rhodophyra), a new component of the Japanese marine flora introduced to Europe. Phycologia 49: 86-96. https://doi.org/10.2216/09-45.1
  17. Kim KY, Nguyen TH, Kurihara H, Kim SM. 2010. ${\alpha}$-glucosidase inhibitory activity of bromophenol purified from the red alga Polyopes lancifolia. J Food Sci 75: 145-150.
  18. Sevanian A, Hochstein P. 1985. Mechanism and consequence of lipid peroxidation in biological systems. Annu Rev Nutr 5: 365-390. https://doi.org/10.1146/annurev.nu.05.070185.002053
  19. Schmidtmann S, Muller M, von Baehr R, Precht K. 1991. Changes of antioxidative homeostasis in patients on chronic haemodialysis. Nephrol Dial Transpl 6: 71-74.
  20. Halliwell B, Gutteridge JMC. 1999. Free Radicals in Biology and Medicine. 3rd ed. Oxford University Press, Oxford, UK. p 617-783.
  21. Seghrouchni I, Drai J, Bannier E, Riviere J, Calmard P, Garcia I, Orgiazzi J, Revol A. 2002. Oxidative stress parameters in type I, type II and insulin-treated type 2 diabetes mellitus; insulin treatment efficiency. Clin Chim Acta 321: 89-96. https://doi.org/10.1016/S0009-8981(02)00099-2
  22. Lee YJ, Kang DG, Kim JS, Lee HS. 2008. Lycopus lucidus inhibits high glucoseinduced vascular inflammation in human umbilical vein endothelial cells. Vasc Pharmacol 48:38-46. https://doi.org/10.1016/j.vph.2007.11.004
  23. Finkel T, Holbrook NJ. 2000. Oxidants, oxidative stress and the biology of aging. Nature 408: 239-247. https://doi.org/10.1038/35041687
  24. Pereira EC, Ferderbar S, Bertolami MC, Faludi AA, Monte O, Xavier HT, Pereira TV, Abdalla DS. 2008. Biomarkers of oxidative stress and endothelial dysfunction in glucose intolerance and diabetes mellitus. Clin Biochem 41: 1454-1460. https://doi.org/10.1016/j.clinbiochem.2008.08.074
  25. Corbett JA, McDaniel ML. 1992. Does nitric oxide mediate autoimmune destruction on ${\beta}$-cells? Possible therapeutic interventions in IDDM. Diabetes 41: 897-903. https://doi.org/10.2337/diabetes.41.8.897
  26. Hogg N, Darley-Usmar VM, Graham A, Moncada S. 1993. Peroxynitrite and atherosclerosis. Biochem Soc Trans 21:358-362. https://doi.org/10.1042/bst0210358
  27. Lee SH, Han JS, Heo SJ, Hwang JY, Jeon YJ. 2009. Protective effects of dieckol isolated from Ecklonia cava against high glucose-induced oxidative stress in human umbilical vein endothelial cells. Toxicol In Vitro 24: 375-381.
  28. Spencer NF, Poynter ME, Im SY, Daynes RA. 1997. Constitutive activation of NF-kappa B in an animal model of aging. Int Immunol 9: 1581-1588. https://doi.org/10.1093/intimm/9.10.1581
  29. Thiemermann C, Ruetten H, Wu CC, Vane JR. 1995. The multiple organ dysfunction syndrome caused by endotoxin in the rat: attenuation of liver dysfunction by inhibitors of nitric oxide synthase. Br J Pharmacol 116: 2845-2851. https://doi.org/10.1111/j.1476-5381.1995.tb15935.x
  30. Liaudet L, Rosselet A, Schaller MD, Markert M, Perret C, Feihl F. 1998. Nonselective versus selective inhibition of inducible nitric oxide synthase in experimental endotoxic shock. J Infect Dis 177: 127-132. https://doi.org/10.1086/513813
  31. Yokozawa T, Kim YA, Kim HY, Lee YA, Nonaka G. 2007. Protective effect of persimmon peel polyphenol against high glucose-induced oxidative stress in LLC-PK(1) cells. Food Chem Toxicol 45: 1979-1987. https://doi.org/10.1016/j.fct.2007.04.018
  32. Wu KK. 1995. Inducible cyclooxygenase and nitric oxide synthase. Adv Pharmacol 33: 179-190. https://doi.org/10.1016/S1054-3589(08)60669-9
  33. Baeuerle PA, Baltimore D. 1996. NF-kappa B: ten years after. Cell 87: 13-20. https://doi.org/10.1016/S0092-8674(00)81318-5
  34. Han M, Wen JK, Zheng B, Zhang DQ. 2004. Acetylbritannilatone suppresses NO and PGE2 synthesis in RAW7 macrophages through the inhibition of iNOS and COX-2 gene expression. Life Sci 75: 675-684. https://doi.org/10.1016/j.lfs.2003.12.022
  35. Du X, Stocklauser-Farber K, Rosen P. 1999. Generation of reactive oxygen intermediates, activation of NF-kappaB, and induction of apoptosis in human endothelial cells by glucose: role of nitric oxide synthase? Free Radic Biol Med 27: 752-763. https://doi.org/10.1016/S0891-5849(99)00079-9
  36. Hattori Y, Hattori S, Sato N, Kasai K. 2000. High-glucoseinduced nuclear factor kappa B activation in vascular smooth muscle cells. Cardiovasc Res 46: 188-197. https://doi.org/10.1016/S0008-6363(99)00425-3
  37. Morigi M, Angioletti S, Imberti B, Donatelli R, Micheletti G, Figliuzzi M, Remuzzi A, Zoja C, Remuzzi G. 1998. Leukocyte- endothelial interaction is augmented by high glucose concentration and hyperglycemia in a NF-${\kappa}B$ dependent fashion. J Clin Invest 101: 1905-1915. https://doi.org/10.1172/JCI656

피인용 문헌

  1. Polyopes lancifolia Extract, a Potent α-Glucosidase Inhibitor, Alleviates Postprandial Hyperglycemia in Diabetic Mice vol.19, pp.1, 2014, https://doi.org/10.3746/pnf.2014.19.1.005
  2. iNOS-derived peroxynitrite mediates high glucose-induced inflammatory gene expression in vascular smooth muscle cells through promoting KLF5 expression and nitration 2017, https://doi.org/10.1016/j.bbadis.2017.07.004
  3. Polyopes lancifolia extracts protect INS-1 pancreatic β cells against high glucose level induced apoptosis vol.23, pp.2, 2014, https://doi.org/10.1007/s10068-014-0086-4
  4. Antioxidant and anti-inflammatory effects of DHK-medicated serum on high glucose-induced injury in endothelial cells vol.16, pp.5, 2017, https://doi.org/10.3892/mmr.2017.7571
  5. Inhibition of long noncoding RNA MALAT1 suppresses high glucose-induced apoptosis and inflammation in human umbilical vein endothelial cells by suppressing the NF-κB signaling pathway vol.98, pp.6, 2013, https://doi.org/10.1139/bcb-2019-0403
  6. Potential Effect of Polyphenolic-Rich Fractions of Corn Silk on Protecting Endothelial Cells against High Glucose Damage Using In Vitro and In Vivo Approaches vol.26, pp.12, 2013, https://doi.org/10.3390/molecules26123665