DOI QR코드

DOI QR Code

Sandstorm Appearance of Pulmonary Alveolar Microlithiasis Incidentally Detected in a Young, Asymptomatic Male

  • Ch'ng, Li Shyan (Department of Biomedical Imaging, Faculty of Medicine, University Malaya Medical Center) ;
  • Bux, Shaik Ismail (Department of Biomedical Imaging, Faculty of Medicine, University Malaya Medical Center) ;
  • Liam, Chong Kin (Department of Medical, Faculty of Medicine, University Malaya Medical Center) ;
  • Rahman, Nazarina Abdul (Department of Pathology, Faculty of Medicine, University Malaya Medical Center) ;
  • Ho, Choon Yan (Department of Pathology, Faculty of Medicine, University Malaya Medical Center)
  • 투고 : 2012.12.12
  • 심사 : 2013.06.27
  • 발행 : 2013.09.01

초록

Pulmonary alveolar microlithiasis (PAM) is a rare chronic disease with paucity of symptoms in contrast to the imaging findings. We present a case of a 24-year-old Malay man having an incidental abnormal pre-employment chest radiograph of dense micronodular opacities giving the classical "sandstorm" appearance. High-resolution computed tomography of the lungs showed microcalcifications with subpleural cystic changes. Open lung biopsy showed calcospherites within the alveolar spaces. The radiological and histopathological findings were characteristic of PAM.

키워드

참고문헌

  1. Wallis C, Whitehead B, Malone M, Dinwiddie R. Pulmonary alveolar microlithiasis in childhood: diagnosis by transbronchial biopsy. Pediatr Pulmonol 1996;21:62-64 https://doi.org/10.1002/(SICI)1099-0496(199601)21:1<62::AID-PPUL11>3.0.CO;2-B
  2. Siddiqui NA, Fuhrman CR. Best cases from the AFIP: Pulmonary alveolar microlithiasis. Radiographics 2011;31:585-590 https://doi.org/10.1148/rg.312105157
  3. Mariotta S, Ricci A, Papale M, De Clementi F, Sposato B, Guidi L, et al. Pulmonary alveolar microlithiasis: report on 576 cases published in the literature. Sarcoidosis Vasc Diffuse Lung Dis 2004;21:173-181
  4. Marchiori E, Goncalves CM, Escuissato DL, Teixeira KI, Rodrigues R, Barreto MM, et al. Pulmonary alveolar microlithiasis: high-resolution computed tomography findings in 10 patients. J Bras Pneumol 2007;33:552-557
  5. Corut A, Senyigit A, Ugur SA, Altin S, Ozcelik U, Calisir H, et al. Mutations in SLC34A2 cause pulmonary alveolar microlithiasis and are possibly associated with testicular microlithiasis. Am J Hum Genet 2006;79:650-656 https://doi.org/10.1086/508263
  6. Barbolini G, Rossi G, Bisetti A. Pulmonary alveolar microlithiasis. N Engl J Med 2002;347:69-70 https://doi.org/10.1056/NEJM200207043470118
  7. Hoshino H, Koba H, Inomata S, Kurokawa K, Morita Y, Yoshida K, et al. Pulmonary alveolar microlithiasis: high-resolution CT and MR findings. J Comput Assist Tomogr 1998;22:245-248 https://doi.org/10.1097/00004728-199803000-00016
  8. Deniz O, Ors F, Tozkoparan E, Ozcan A, Gumus S, Bozlar U, et al. High resolution computed tomographic features of pulmonary alveolar microlithiasis. Eur J Radiol 2005;55:452-460 https://doi.org/10.1016/j.ejrad.2005.01.010
  9. Sumikawa H, Johkoh T, Tomiyama N, Hamada S, Koyama M, Tsubamoto M, et al. Pulmonary alveolar microlithiasis: CT and pathologic findings in 10 patients. Monaldi Arch Chest Dis 2005;63:59-64
  10. Mascie-Taylor BH, Wardman AG, Madden CA, Page RL. A case of alveolar microlithiasis: observation over 22 years and recovery of material by lavage. Thorax 1985;40:952-953 https://doi.org/10.1136/thx.40.12.952
  11. Tachibana T, Hagiwara K, Johkoh T. Pulmonary alveolar microlithiasis: review and management. Curr Opin Pulm Med 2009;15:486-490 https://doi.org/10.1097/MCP.0b013e32832d03bb

피인용 문헌

  1. Calcified Curschmann's spirals and microliths in sputum smears from a case of pulmonary alveolar microlithiasis vol.45, pp.12, 2013, https://doi.org/10.1002/dc.23782
  2. Pulmonary Alveolar Microlithiasis: A Unique Case of Familial PAM Complicated by Transplant Rejection vol.2021, pp.None, 2013, https://doi.org/10.1155/2021/6674173