Korean Journal of Radiology

The Korean Society of Radiology (대한영상의학회)
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Primary Breast Amyloidosis Presenting as Microcalcifications Only

  • Shim, Youngsub (Department of Radiology, Gachon University Gil Hospital) ;
  • Kim, Min Jung (Department of Radiology, Gachon University Gil Hospital) ;
  • Ryu, Han Suk (Department of Pathology, Seoul National University Hospital) ;
  • Park, Sung Hee (Department of Radiology, Chung-Ang University Hospital, Chung-Ang University College of Medicine)
  • Received : 2013.05.21
  • Accepted : 2013.07.04
  • Published : 2013.09.01
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Abstract

Amyloidosis is a rare disease characterized by the formation of pathological protein deposits in organs or tissues. It is typically a systemic disease which can occur in a localized form. Amyloidosis of the breast is uncommon. Common mammographic findings of breast amyloidosis are multiple nodules with or without calcifications. We report a case of primary localized breast amyloidosis presenting suspicious microcalcifications on mammography without associated masses. Mammography in a 72-year-old woman displayed multiple, linearly distributed, irregular and rod-like calcifications in the subareolar area of the left breast. The patient underwent surgical excision under mammo-guided needle localization and the pathology was confirmed to be breast amyloidosis.

Keywords

References

  1. Ngendahayo P, Faverly D, Hérin M. Primary breast amyloidosis presenting solely as nonpalpable microcalcifications: a case report with review of the literature. Int J Surg Pathol 2013;21:177-180 https://doi.org/10.1177/1066896912457203
  2. Diaz-Bustamante T, Iribar M, Vilarrasa A, Benito A, Lopez-Rios F. Primary amyloidosis of the breast presenting solely as microcalcifications. AJR Am J Roentgenol 2001;177:903-904 https://doi.org/10.2214/ajr.177.4.1770903
  3. Gluck BS, Cabrera J, Strauss B, Ricca R, Brancaccio W, Tamsen A. Amyloid deposition of the breast. AJR Am J Roentgenol 2000;175:1590 https://doi.org/10.2214/ajr.175.6.1751590
  4. Athanasiou A, Vanel D, Tomasic G, Bidault F, Balleyguier C. Quiz. Primary breast amyloidosis. Eur J Radiol 2007;61:184-186 https://doi.org/10.1016/j.ejrad.2006.08.031
  5. Patel B, Torbiak C, Danyluk JM, Callahan D. Primary amyloidosis of the breast presenting as nonpalpable microcalcifications: case report. Can Assoc Radiol J 2003;54:277-278
  6. American College of Radiology. Breast imaging reporting and data $system^{(R)}$ (BI-$RADS^{(R)}$) Atlas. 4th ed. Reston, VA: American College of Radiology, 2003
  7. Luo JH, Rotterdam H. Primary amyloid tumor of the breast: a case report and review of the literature. Mod Pathol 1997;10:735-738
  8. Sabate JM, Clotet M, Torrubia S, Guerrero R, Pineda R, Lerma E, et al. Localized amyloidosis of the breast associated with invasive lobular carcinoma. Br J Radiol 2008;81:e252-e254 https://doi.org/10.1259/bjr/84520845
  9. Rocken C, Kronsbein H, Sletten K, Roessner A, Bassler R. Amyloidosis of the breast. Virchows Arch 2002;440:527-535 https://doi.org/10.1007/s00428-001-0555-z
  10. Fu K, Bassett LW. Mammographic findings of diffuse amyloidosis and carcinoma of the breast. AJR Am J Roentgenol 2001;177:901-902 https://doi.org/10.2214/ajr.177.4.1770901

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