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A Case of Rheumatoid Pneumoconiosis Presenting with Pleuritis and Pericarditis

흉막염과 심장막염으로 발현한 류마티스성 진폐증 1예

  • Park, Myung Soo (Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine) ;
  • Kang, Dae Gil (Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine) ;
  • Jung, Eun Ju (Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine) ;
  • Oh, Ki Jong (Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine) ;
  • Sim, Jong Seop (Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine) ;
  • Kim, Eun Jung (Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine) ;
  • Kim, Changhwan (Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine)
  • 박명수 (한림대학교 의과대학 내과학교실, 강동성심병원 내과) ;
  • 강대길 (한림대학교 의과대학 내과학교실, 강동성심병원 내과) ;
  • 정은주 (한림대학교 의과대학 내과학교실, 강동성심병원 내과) ;
  • 오기종 (한림대학교 의과대학 내과학교실, 강동성심병원 내과) ;
  • 심종섭 (한림대학교 의과대학 내과학교실, 강동성심병원 내과) ;
  • 김은정 (한림대학교 의과대학 내과학교실, 강동성심병원 내과) ;
  • 김창환 (한림대학교 의과대학 내과학교실, 강동성심병원 내과)
  • Received : 2012.07.28
  • Accepted : 2012.09.04
  • Published : 2013.03.01

Abstract

Caplan's syndrome is characterized by multiple small distinct nodules with progressive massive fibrosis and rheumatic arthritis in pneumoconiosis. Although pleural effusions occur infrequently as an extra-articular manifestation, pleuritis can develop without joint involvement in patients with rheumatoid arthritis. We treated an 81-year-old man who had been diagnosed with silicosis with progressive massive fibrosis. He suffered from progressive dyspnea, and chest computed tomography (CT) and echocardiography revealed pleural and pericardial effusions. We speculated that the multiple serositis was related to a rheumatic disorder because the rheumatic factor was elevated in both the pleural and pericardial effusions. After corticosteroid treatment, the serositis improved. We suggest that this case is an atypical pattern of Caplan's syndrome presenting as serositis without arthritis. Rheumatoid serositis should be considered as the cause of pleural or pericardial effusions in patients with pneumoconiosis.

Caplan 증후군이 발표되면서 류마티스관절염과 진폐증의 관련성이 알려지기 시작하였다. Caplan 증후군은 전형적으로 류마토이드인자 양성인 류마티스관절염이 나타나는 진폐증 환자에서 진단할 수 있다. 류마티스관절염 환자에서 흉막질환은 드물지 않게 나타나는 합병증으로, 흉막 삼출액에서 류마토이드 인자가 양성으로 나타나는 특징적인 양상을 보인다. 일부에서는 흉막 삼출이 류마티스관절염의 첫 증상으로 발현되기도 하며, 관절증상이 나타나지 않는 경우도 있다. 저자들은 흉막과 심장막 삼출이 동반된 규폐증 환자의 혈청과 삼출액에서 류마티스 인자의 증가를 확인하고 스테로이드 치료 후 호전을 경험한 증례가 있어, 이를 장막염으로 발현한 Caplan 증후군의 비전형적인 형태로 판단하여 보고하는 바이다.

Keywords

References

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