DOI QR코드

DOI QR Code

A Case of Acute Recurrent Pancreatitis Caused by Metastasis of Renal Cell Carcinoma to the Ampulla of Vater

신세포암의 바터 팽대부 전이에 의한 급성 재발성 췌장염

  • Kang, Jong Sik (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Myung-Hwan (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Lee, Sung Koo (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Lee, Jae Kwang (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Lee, Min Jung (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Jung, Min Jung (Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Jin Hee (Department of Radiology, Asan Medical Center, University of Ulsan College of Medicine)
  • 강종식 (울산대학교 의과대학 서울아산병원 내과) ;
  • 김명환 (울산대학교 의과대학 서울아산병원 내과) ;
  • 이성구 (울산대학교 의과대학 서울아산병원 내과) ;
  • 이재광 (울산대학교 의과대학 서울아산병원 내과) ;
  • 이민정 (울산대학교 의과대학 서울아산병원 내과) ;
  • 정민정 (울산대학교 의과대학 서울아산병원 병리과) ;
  • 김진희 (울산대학교 의과대학 서울아산병원 영상의학과)
  • Received : 2012.03.01
  • Accepted : 2012.04.04
  • Published : 2013.02.01

Abstract

Metastasis of renal cell carcinoma to the ampulla of Vater is a rare occurrence. We report a case of acute recurrent pancreatitis caused by metastasis of renal cell carcinoma to the ampulla of Vater. The patient manifested acute recurrent pancreatitis 10 years after a nephrectomy for renal cell carcinoma and was presumed to have obstructive pancreatitis secondary to an ampullary mass. Duodenoscopy revealed an ampullary mass, and the patient was finally diagnosed with metastatic renal cell carcinoma. With insertion of a pancreatic stent via endoscopic retrograde cholangiopancreatography, the acute pancreatitis was resolved. When an ampullary mass is observed in a patient with a history of renal cell carcinoma, the possibility of ampullary metastasis of the renal cell carcinoma should be considered, as this is a potential etiology of acute recurrent pancreatitis.

신세포암은 드물지만 바터 팽대부로 전이될 수 있으며, 이로 인해 췌액의 흐름을 방해하여 재발성 급성 췌장염을 유발할 수 있다. 수술로 절제가 어려운 경우 내시경 역행성 담췌관 조영술 시술을 통한 주췌관 내로의 스텐트 삽입이 췌장염 치료에 도움이 될 수 있다.

Keywords

References

  1. Adamo R, Greaney PJ Jr, Witkiewicz A, Kennedy EP, Yeo CJ. Renal cell carcinoma metastatic to the duodenum: treatment by classic pancreaticoduodenectomy and review of the literature. J Gastrointest Surg 2008;12:1465-1468. https://doi.org/10.1007/s11605-007-0426-2
  2. Janzen RM, Ramj AS, Flint JD, Scudamore CH, Yoshida EM. Obscure gastrointestinal bleeding from an ampullary tumour in a patient with a remote history of renal cell carcinoma: a diagnostic conundrum. Can J Gastroenterol 1998;12:75-78. https://doi.org/10.1155/1998/429832
  3. Rustagi T, Rangasamy P, Versland M. Duodenal bleeding from metastatic renal cell carcinoma. Case Rep Gastroenterol 2011;5:249-257. https://doi.org/10.1159/000327996
  4. Chang WT, Chai CY, Lee KT. Unusual upper gastrointestinal bleeding due to late metastasis from renal cell carcinoma: a case report. Kaohsiung J Med Sci 2004;20:137-141. https://doi.org/10.1016/S1607-551X(09)70098-1
  5. Venu RP, Geenen JE. Diagnosis and treatment of diseases of the papilla. Clin Gastroenterol 1986;15:439-456.
  6. Leese T, Neoptolemos JP, West KP, Talbot IC, Carr-Locke DL. Tumours and pseudotumours of the region of the ampulla of Vater: an endoscopic, clinical and pathological study. Gut 1986;27:1186-1192. https://doi.org/10.1136/gut.27.10.1186
  7. Thyavihally YB, Mahantshetty U, Chamarajanagar RS, Raibhattanavar SG, Tongaonkar HB. Management of renal cell carcinoma with solitary metastasis. World J Surg Oncol 2005;3:48. https://doi.org/10.1186/1477-7819-3-48
  8. Delhaye M, Matos C, Arvanitakis M, Deviere J. Pancreatic ductal system obstruction and acute recurrent pancreatitis. World J Gastroenterol 2008;14:1027-1033. https://doi.org/10.3748/wjg.14.1027
  9. Moon SH, Kim MH, Park do H, et al. Modified fully covered self-expandable metal stents with antimigration features for benign pancreatic-duct strictures in advanced chronic pancreatitis, with a focus on the safety profile and reducing migration. Gastrointest Endosc 2010;72:86-91. https://doi.org/10.1016/j.gie.2010.01.063
  10. Park do H, Kim MH, Moon SH, Lee SS, Seo DW, Lee SK. Feasibility and safety of placement of a newly designed, fully covered self-expandable metal stent for refractory benign pancreatic ductal strictures: a pilot study (with video). Gastrointest Endosc 2008;68:1182-1189. https://doi.org/10.1016/j.gie.2008.07.027